A5050016814- Ovarian cancer diagnosis and treatment
- Cancer, Lipids, and Metabolism
- Lipoproteins and Cardiovascular Health
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Advanced Polymer Synthesis and Characterization
- Chemokine receptors and signaling
- Protease and Inhibitor Mechanisms
- Ferroptosis and cancer prognosis
- biodegradable polymer synthesis and properties
- Polymer crystallization and properties
- Peptidase Inhibition and Analysis
Zhejiang University
2013-2024
Hangzhou First People's Hospital
2021-2024
Westlake University
2024
First Affiliated Hospital Zhejiang University
2021
State Key Laboratory of Chemical Engineering
2013
Abstract Immunotherapy is becoming a promising cancer treatment for microsatellite-instability-high (MSI-H) pan-cancers, and combination therapy with IO drugs anti-angiogenesis or antibody-drug-conjugates considered as first-line advanced unresectable hepatocellular carcinoma bladder respectively. Though human CD34+HSC PBMC humanized models are valuable tools to investigate the in vivo function mechanism of immuno-oncology drugs, allogeneic reaction between targeted tissue immune system...
<title>Abstract</title> Ovarian cancer (OC) is the most lethal female genital worldwide. Most patients exhibit resistance to immunotherapy. CMTM6 has been implicated in various tumorigenic processes and immune regulation. This study aims investigate role of OC progression its function immunity. We utilized GEPIA GTBA databases analyze relationships among OC, CMTM6, PD-L1. The was further examined through immunohistochemical analysis patient tumor tissues extensive cell experiments using...
Abstract Aim Sex‐determining region Y‐related high‐mobility group box 4 (SOX4) has been reported to play a carcinogenic role in endometrial cancer (EC). However, the biological function and regulatory mechanisms of SOX4 ferroptosis during progression EC are still unknown. Methods The mRNA protein levels were scrutinized by quantitative reverse‐transcription polymerase chain reaction western blot, respectively. cell viability proliferative capability determined counting kit‐8 assay...
Abstract Background: The effect of serum lipids on ovarian cancer is controversial. We conduct this study to evaluate the prognostic value preoperative plasma lipid profile in patients with cancer. Methods: medical records 156 epithelial who underwent surgical resection our department were retrospectively reviewed and analyzed. Serum profiles, including total cholesterol (TC), high-density lipoprotein (HDL-C), low-density (LDL-C), triglyceride (TG), apolipoprotein A-Ⅰ (apoA-Ⅰ), B (apoB)...
Abstract Background The effect of serum lipids on ovarian cancer is controversial. We conduct this study to evaluate the prognostic value preoperative plasma lipid profile in patients with cancer. Methods medical records 156 epithelial who underwent surgical resection our department were retrospectively reviewed and analyzed. Serum profiles, including total cholesterol (TC), high-density lipoprotein (HDL-C), low-density (LDL-C), triglyceride (TG), apolipoprotein A-Ⅰ (apoA-Ⅰ), B (apoB)...