- Nerve Injury and Rehabilitation
- Nerve injury and regeneration
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Peripheral Nerve Disorders
- Reconstructive Surgery and Microvascular Techniques
- Orthopedic Surgery and Rehabilitation
- Orthopaedic implants and arthroplasty
- Muscle activation and electromyography studies
- Musculoskeletal pain and rehabilitation
- Total Knee Arthroplasty Outcomes
- Neuroscience and Neural Engineering
- Bone fractures and treatments
- Sarcoma Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Tendon Structure and Treatment
- Pediatric Pain Management Techniques
- Planarian Biology and Electrostimulation
- Anesthesia and Pain Management
- Burn Injury Management and Outcomes
- Shoulder and Clavicle Injuries
- Pain Management and Treatment
- Aortic Disease and Treatment Approaches
- Shoulder Injury and Treatment
- Orthopedic Infections and Treatments
Istituto Ortopedico Rizzoli
2018-2024
University of Pennsylvania
2023
Istituti di Ricovero e Cura a Carattere Scientifico
2018-2022
University of Milan
2022
Istituto Ortopedico Galeazzi
2022
Istituto Ortopedico Gaetano Pini
2021
University of Bologna
2017-2019
Ospedale Koelliker
2018
Painful conditions such as residual limb pain (RLP) and phantom (PLP) can manifest after amputation. The mechanisms underlying postamputation pains are diverse should be addressed accordingly. Different surgical treatment methods have shown potential for alleviating RLP due to neuroma formation - commonly known a lesser degree PLP. Two reconstructive interventions, namely targeted muscle reinnervation (TMR) regenerative peripheral nerve interface (RPNI), gaining popularity in with promising...
Over the past decade, field of prosthetics has witnessed significant progress, particularly in development surgical techniques to enhance functionality prosthetic limbs. Notably, novel interventions have had an additional positive outcome, as individuals with amputations reported neuropathic pain relief after undergoing such procedures. Subsequently, gained increased prominence treatment postamputation pain, including one advancement - targeted muscle reinnervation (TMR). TMR involves a...
Periprosthetic hip infections with severe proximal femoral bone loss may require the use of limb salvage techniques, but no agreement exists in literature regarding most effective treatment. Aim this study is to analyze infection eradication rate and implant survival at medium-term follow-up patients treated megaprostheses for periprosthetic loss.Twenty-one consecutive were retrospectively reviewed a mean 64-month (24-120). Functional pain scores, microbiological, radiological intraoperative...
The anatomical variations of the brachial plexus are important to be reported, in order avoid their damage during upper-limb surgical procedures. Despite frequent documented abnormalities pathway musculocutaneous and median nerves, variation accurately described present case is unusual see: it does not perfectly come under any classifications proposed literature. During dissection right an old male Caucasian cadaver a communicating branch between nerve was observed. Proximally It originated...
Nerve repair poses a significant surgical challenge, and much research on this topic for improvement in reconstruction of segmental defects is ongoing. The aims the study were to reconfirm accuracy safety previously described nerve decellularization method larger experimental population rabbits, as well human nerves, establish vivo efficacy new-concept mixed graft, comprising autologous acellular allograft components within same graft.Acellular allografts implanted into tibial 5 rabbits...
Over the past decade, field of prosthetics has witnessed significant progress, particularly in development surgical techniques to enhance functionality prosthetic limbs. Notably, novel interventions have had an additional positive outcome, as individuals with amputations reported neuropathic pain relief after undergoing such procedures. Subsequently, gained increased prominence treatment postamputation pain, including one advancement - targeted muscle reinnervation (TMR). TMR involves a...
Background: The posterior trunk has been considered a challenging area to reconstruct following soft tissue tumor excision because of the shortage local donor sites. advent innovative procedures such as perforator flaps radically changed this perspective and offered new approach problem. Methods: Upon review literature personal experiences senior author, an algorithm is developed according most updated procedure, combined with more conventional options that maintain role in decision-making....
The free vascularized fibula transfer has become a widely utilized method in reconstructive surgery, with successful applications across various anatomical areas. biological properties of the graft, including its ability to fuse recipient bone, repair fractures, and remodel new biomechanical environments, have been key efficacy. However, stable bone fixation is crucial for fusion prevent complications like non-union. While early approaches focused on minimally invasive techniques preserve...
Surgical procedures, including nerve reconstruction and end-organ muscle reinnervation, have become more prominent in the prosthetic field over past decade. Primarily developed to increase functionality of limbs, these surgical procedures also been found reduce postamputation neuropathic pain. Today, some are performed frequently for management prevention pain than fitting, indicating a significant need effective solutions One notable emerging procedure this context is Regenerative...
Surgical procedures, including nerve reconstruction and end-organ muscle reinnervation, have become more prominent in the prosthetic field over past decade. Primarily developed to increase functionality of limbs, these surgical procedures also been found reduce postamputation neuropathic pain. Today, some are performed frequently for management prevention pain than fitting, indicating a significant need effective solutions One notable emerging procedure this context is Regenerative...
Defects of the peripheral nervous system are extremely frequent in trauma and surgeries have high socioeconomic costs. If direct suture a lesion is not possible, i.e., nerve gap > 2 cm, it necessary to use grafts. While gold standard autograft, has disadvantages related its harvesting, with an inevitable functional deficit further morbidity. An alternative autografting represented by acellular allograft (ANA), which avoids autograft harvesting fresh rejection. In this research, authors...
Anomalies of the brachial plexus including distribution nerves as well its terminal branches in upper limb have been largely described literature. In this case report we describe a further variant formation identified during routine anatomical dissection right 62-year-old Caucasian female cadaver. On side no musculocutaneous nerve was identified, median formed expected but short extra branch communicating between lateral cord and medial head appeared. Coracobrachialis muscle innervated by...
Unicondylar fractures of the femur are uncommon injuries that can occur in sagittal or, less frequently, coronal plane (Hoffa fractures). Distal femoral usually described following AO/OTA Classification system which includes extra-articular, partial articular and intra-articular injuries, further divided three types based on pattern comminution. Accurate reduction stable fixation needed especially order to allow early mobilization reduce complications such as knee stiffness, malunion or...
PurposeDespite modern advancements in the treatment of late stages wrist joint degeneration, few reliable options exist for patients requiring motion-preserving reconstruction their radiocarpal and midcarpal joints. Vascularized composite allotransplantation (VCA) could be considered an option future. The goal this study was to describe relevant anatomy design a potential surgical technique VCA.MethodsAnatomic studies were performed on 17 human upper extremities. arterial system each cadaver...
During the last year we found a plethora of variants while performing anatomical dissection on human cadavers. In present report describe previously quoted variation morphologies focusing their clinical relevance. The first variant observed was left vertebral artery (VA) arising from aortic arch, it is in 5% to 8 % individuals. VA origin showed remarkably higher incidence arterial than subclavian origin. Also, pattern has be taken into consideration before any intervention local region as...