ABSTRACT This article provides experimental evidence for the role of lexically specific representations in processing passive sentences and considerable education-related differences comprehension construction. The experiment measured response time decision accuracy participants with high low academic attainment using an online task that compared active containing verbs strongly associated constructions, as determined by collostructional analysis. As predicted usage-based accounts,...

Reading comprehension is influenced by sources of variance associated with the reader and task. To gain insight into complex interplay multiple influence, we employed crossed random-effects item response models. These models allowed us to simultaneously examine degree which variables related type passage student characteristics students' (n = 94; mean age 11.97 years) performance on two indicators reading comprehension: different types questions fluency. We found that word recognition,...

Journal Article The Central Uptake of β-Adrenoceptor Antagonists Get access M D Day, Day Department Physiology, University Nottingham, Nottingham NG7 2UH Search for other works by this author on: Oxford Academic Google Scholar B A Hemsworth, Hemsworth Pharmacy, Aston in Birmingham, Birmingham B4 7ET J Street Pharmacy and Pharmacology, Volume 29, Issue Supplement_1, December 1977, Page 52P, https://doi.org/10.1111/j.2042-7158.1977.tb11520.x Published: 12 April 2011

1 The accumulation and release of [3H]-propranolol [3H]-atenolol were examined in synaptosomes from rat cerebral cortex. 2 Synaptosomes accumulated 20 pmol propranolol 0.6 atenolol mg−1 protein when incubated at 30°C with radiolabeled drugs (0.1 μm). 3 Exposure propranolol-loaded to elevated K+, Rb+ or Cs+ evoked a concentration-dependent increase efflux. action these ions releasing was highly correlated their ability produce synaptosomal membrane depolarization, as estimated the...

Propranolol is accumulated at several adrenergic neuroeffector junctions after chronic oral administration in the dog, and released subsequently during sympathetic nerve stimulation. In present study, accumulation, subcellular localization release of propranolol was examined rat cortical synaptosomes. Synaptosomal accumulation rapid attained equilibrium within 1 min. uptake increased a nonlinear manner with increasing drug concentration medium, but could not be fully saturated over range...

Stereoselective storage and release of the cardioselective beta adrenergic receptor antagonist atenolol was studied using cultured PC12 cells as a neural model. [3H]Atenolol efflux from preloaded increased 4-fold in response to membrane depolarization by elevated extracellular potassium (50 mM). [3H]Norepinephrine enhanced 4.5-fold under same conditions. Potassium-induced both [3H] [3H]norepinephrine inhibited completely absence calcium. also reduced calcium channel nifedipine (IC50 = 1.6...

The uptake of (±)‐[ 14 C]‐oxprenolol and C]‐propranolol has been studied in rat lung slices. loss these two radiolabelled β‐adrenoceptor antagonists from pre‐loaded slices also studied. Over the concentration range (3.3 × 10 −7 m to 1.7 −3 m) a biphasic both compounds was observed. At concentrations below 1.5 −4 approximately, there some evidence saturability, but at higher appeared be linear function drug concentration. 6.6 −6 respectively, oxprenolol propranolol significantly reduced by...

Journal Article Lung Accumulation of Some β-Adrenoceptor Antagonists Get access J A Street, Street Department Pharmacy, University Aston, Birmingham B4 7ET, England Search for other works by this author on: Oxford Academic Google Scholar I Gonda, Gonda H Parkinson, Parkinson B Hemsworth Pharmacy and Pharmacology, Volume 30, Issue Supplement_1, December 1978, Page 56P, https://doi.org/10.1111/j.2042-7158.1978.tb10763.x Published: 12 April 2011

This study examines the effects of education and input as predictors adult second language acquisition in naturalistic contexts. L1 Albanian learners Greek who differed amount schooling (from 4 to 16 years) length residence 8 27 completed elicitation tasks that tested mastery gender number agreement, past tense morphology. In addition, samples spontaneous speech were assessed for fluency, grammatical complexity, lexical richness order establish learners’ overall proficiency L2. We...

Abstract We present experimental evidence suggesting that frequency and literacy predict online processing comprehension of subject-verb agreement constructions by adult native speakers English. measured participants’ eye fixations, reaction times, response accuracy in a forced-choice task using audio-visual eye-tracking paradigm. Participants completed battery tasks, inc. the Literacy Rating Scale (Tarone et al., Second Language Oracy-Oxford Applied Linguistics, Oxford University Press,...