A5006602320- Protein Interaction Studies and Fluorescence Analysis
- Gout, Hyperuricemia, Uric Acid
- Proteins in Food Systems
- Phytochemicals and Antioxidant Activities
- Traditional Chinese Medicine Analysis
- Pharmacological Effects of Natural Compounds
- X-ray Diffraction in Crystallography
- Natural Antidiabetic Agents Studies
- Food composition and properties
- Polysaccharides Composition and Applications
- Crystallization and Solubility Studies
- Drug Transport and Resistance Mechanisms
- Carbohydrate Chemistry and Synthesis
- Crystallography and molecular interactions
- Hepatitis C virus research
- Moringa oleifera research and applications
- Synthesis of Organic Compounds
- Phytochemistry and Biological Activities
- Eosinophilic Disorders and Syndromes
- Surfactants and Colloidal Systems
- Ginseng Biological Effects and Applications
- Ion Transport and Channel Regulation
- Biopolymer Synthesis and Applications
- Phytase and its Applications
- Nanocomposite Films for Food Packaging
Anhui Polytechnic University
2018-2025
Wuhu Institute of Technology
2018-2020
China Pharmaceutical University
2016-2018
Jinan University
2014-2016
An integrated method was explored to investigate the structure–activity relationship and interaction mechanism between a library of natural flavonoids α-glucosidase.
Gliadin, as a main component of wheat storage protein, is used drug encapsulation and delivery system owing to its specific characteristics. Flavonoids are regarded active natural products with variety pharmacological effects. In this study, an integrated method including UV-vis, fluorescence, FT-IR spectroscopy molecular modelling was applied explore the structure-affinity relationship interaction nature between library flavonoids gliadin. The characteristic UV-vis spectral changes gliadin...
Zein-gum arabic-tea polyphenols ternary complex nanoparticles have been developed for the encapsulation of luteolin, but there are still shortages existed in their particle properties such as efficiency, stability, and release ability luteolin. To improve performance, calcium ions (Ca2+) were employed a cross-linking stabilizer to investigate effects on functional performance. Particle parameters, physicochemical antioxidant activity, vitro simulated gastrointestinal digestion evaluated...
Abstract Cardiotonic steroids (CTS) are clinically important drugs for the treatment of heart failure owing to their potent inhibition cardiac Na + , K -ATPase (NKA). Bufadienolides constitute one two major classes CTS, but little is known about how they interact with NKA. We report a remarkable stereoselectivity NKA by native 3β-hydroxy bufalin over 3α-isomer, yet replacing group larger polar groups in same configuration enhances inhibitory potency. Binding 13 C-labelled glycosyl...
α-Glucosidase has emerged as an important target for type 2 diabetes mellitus. Salvia miltiorrhiza is a widely used traditional Chinese medicine. The interaction between the chemicals of S. and α-glucosidase are still not clear, need to be deeply investigated. Herein, integrated approach consisting computational analysis experimental studies was employed illustrate interactions α-glucosidase. Molecular docking simulations were performed reveal proposed binding characteristics identified in...
An integrated approach was used to explore the interaction between <italic>Salvia miltiorrhiza</italic> and xanthine oxidase combined with enzyme channel blocking.