A5022224129- Neuropeptides and Animal Physiology
- Biochemical effects in animals
- Peptidase Inhibition and Analysis
- Neonatal Respiratory Health Research
- Noise Effects and Management
- Cardiovascular Disease and Adiposity
- Neuroendocrine regulation and behavior
- Infant Nutrition and Health
- Glycosylation and Glycoproteins Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Mesenchymal stem cell research
- Ubiquitin and proteasome pathways
- Magnesium in Health and Disease
- Alkaline Phosphatase Research Studies
- Coronary Interventions and Diagnostics
- Signaling Pathways in Disease
- Therapeutic Uses of Natural Elements
- Protein Tyrosine Phosphatases
- Birth, Development, and Health
- Renal function and acid-base balance
National Academy of Sciences of Armenia
2008-2025
H.Buniatian Institute of Biochemistry
2008-2025
Metastatic chondrosarcoma is a bone malignancy not responsive to conventional therapies; new approaches and therapies are urgently needed. We have previously reported that mTORC1 inhibitor, antitumorigenic cytostatic proline rich polypeptide 1 (PRP-1), galarmin caused significant upregulation of tumor suppressors including TET1/2 SOCS3 (known be involved in inflammatory processes), downregulation oncoproteins embryonic stem cell marker miR-302C its targets Nanog, c-Myc Bmi-1 human...
A new type of bioactive polypeptides the neurosecretory hypothalamus called proline‑rich peptides (PRPs), which are isolated from bovine granules neurohypophysis, synthesized in form a common precursor protein (neurophysin vasopressin‑associated glycoprotein). Proline‑rich polypetide 1 (PRP‑1; also known as galarmin) is comprised 15 amino acids residues, and has been suggested to possess anti‑neurodegenerative, immunoregulatory, hematopoietic, antimicrobial antitumor properties. The...
Keywords: rat brain plasticity, prenatal immobilization stress, GFAP-, nestin-, stem cells-, PRP-1-immuno-reactive structures
Ischemic heart disease is a rather insidious condition with high mortality rate, especially in developing countries, which also affects Armenia. Therefore, the issue of most effective treatment for this particularly pressing. This will be facilitated by more thorough research on atherosclerosis arterioles. The ability to visualize and assess pathological vascular growth 5-point scale provided one modern methods using semi-thin epoxy sections stained Azure II. bioptates right atrial auricles...