A5039422643- Tuberculosis Research and Epidemiology
- COVID-19 epidemiological studies
- Pneumonia and Respiratory Infections
- Malaria Research and Control
- COVID-19 Pandemic Impacts
- Mosquito-borne diseases and control
- Mycobacterium research and diagnosis
- Viral Infections and Outbreaks Research
- Infectious Diseases and Tuberculosis
- Global Maternal and Child Health
- HIV/AIDS Impact and Responses
- Healthcare Systems and Reforms
- Disaster Management and Resilience
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Diagnosis and treatment of tuberculosis
- Vaccine Coverage and Hesitancy
- ICT Impact and Policies
- Chronic Disease Management Strategies
- Census and Population Estimation
- Parasite Biology and Host Interactions
- ICT in Developing Communities
- Global Health Care Issues
- Influenza Virus Research Studies
- Business Strategies and Management Research
University of Liverpool
2019-2025
Malawi-Liverpool-Wellcome Trust Clinical Research Programme
2019-2025
University of Malawi
2020-2025
Liverpool School of Tropical Medicine
2020-2024
Wageningen University & Research
2020
Amsterdam UMC Location University of Amsterdam
2020
Amsterdam University Medical Centers
2020
University of Maryland, Baltimore
2020
Ministry of Health
2017
Queen Elizabeth Central Hospital
2017
The study sought to assess the sources of revenue for local authorities in Zambia; a case Lusaka city council. utilized and investigative research designs. used sample size 40 respondents. questionnaires data was analyzed using descriptive statistics thematic analysis. found that majority respondents were male (71%) while 29% female. also 50% youths, 31% adults 19% elderly Further, highest level education obtained by (57%) had diplomas followed those with bachelor’s degrees (29%). On...
Understanding human mixing patterns relevant to infectious diseases spread through close contact is vital for modelling transmission dynamics and optimisation of disease control strategies. Mixing in low-income countries like Malawi are not well known.
Background: Globally, the burden of tuberculosis (TB) falls more on men than women and children, there are large gaps between at all stages exposure, disease incidence, treatment. We examined impact addressing determinants these gender in Kenya, Malawi, Nigeria, Uganda. Methods Findings: created a deterministic transmission model TB, with strata for sex, age, HIV co-infection antiretroviral therapy, calibrated to country-specific data prevalence, mortality, notifications 2010 2022. then...
Prompt and effective malaria treatment are key in reducing transmission, disease severity mortality. With the current scale-up of artemisinin-based combination therapy (ACT) coverage, there is need to focus on challenges affecting implementation intervention. Routine indicators utilization neglecting quality. A health system rural Malawi was assessed for uncomplicated children. cross-sectional facility survey conducted six centres around Majete Wildlife Reserve Chikwawa district using a...
Recent evidence shows rapidly changing tuberculosis (TB) epidemiology in Southern and Eastern Africa, with need for subdistrict prevalence estimates to guide targeted interventions. We conducted a pulmonary TB survey estimate current burden Blantyre city, Malawi. From May 2019 March 2020, 115 households middle/high-density residential Blantyre, were randomly-selected from each of 72 clusters. Consenting eligible participants (household residents ≥ 18 years) interviewed, including cough (any...
Mass drug administration (MDA) with azithromycin (AZ) is being considered as a strategy to promote child survival in sub-Saharan Africa, but the mechanism by which AZ reduces mortality unclear. To better understand nature and extent of protection provided AZ, we explored profile time since administration, using data from household-randomized, placebo-controlled trial Burkina Faso Mali.
Abstract Recent evidence shows rapidly changing tuberculosis (TB) epidemiology in Southern and Eastern Africa, with need for subdistrict prevalence estimates to guide targeted interventions. We conducted a TB survey estimate current burden Blantyre city, Malawi. From May 2019 March 2020, 215 households middle/high-density residential Blantyre, were randomly-selected from each of 72 clusters. Consenting eligible participants (household residents ≥ 18 years) interviewed, including cough (any...
Tuberculosis (TB) transmission and prevalence are dynamic over time , heterogeneous within populations . Public health programmes therefore require up-to-date accurate epidemiological data to appropriately allocate resources target interventions track progress towards End TB goals Current methods of surveillance often rely on case notifications which biased by access healthcare disease surveys highly resource-intensive requiring many tens thousands people be tested identify high-risk groups...
Urgent improvements in the diagnosis and management of Mycobacterium tuberculosis infection are required to reach End TB goals. Conventional interferon-gamma release assays (IGRAs), such as QuantiFERON-TB Gold Plus (QFT-Plus), require substantial laboratory infrastructure large blood volumes, limiting use high-burden settings. The QIAreach (QIAreach QFT) was developed overcome these challenges but has not previously been evaluated field conditions a low-income, country, or at scale children....
Abstract Background House improvement (HI) to prevent mosquito house entry, and larval source management (LSM) targeting aquatic stages development into adult forms, are promising complementary interventions current malaria vector control strategies. Lack of evidence on costs cost-effectiveness community-led implementation HI LSM has hindered wide-scale adoption. This study presents an incremental cost analysis LSM, in a cluster-randomized, factorial design trial, addition standard national...
Malawi is midway through its current Malaria Strategic Plan 2017-2022, which aims to reduce malaria incidence and deaths by at least 50% 2022. Malariometric data are available with health surveillance housed in District Health Information Software 2 (DHIS2) household survey from two recent Indicator Surveys (MIS) a Demographic Survey (DHS). Strengths weaknesses of the were discussed during consultative meeting Lilongwe, July 2019. The first 3 days included in-depth exploration analysis 13...
It has long been recognised that the health-related Millennium Development Goals cannot be achieved without strengthened health systems. This article presents most recent World Health Organization framework for strengthening systems and considers how economics research can used to measure achievements against each of goals framework. Benefits incorporating tools into operational are highlighted. Finally, economic placed within an impact assessment facilitates capture considerations in...
Abstract Introduction Understanding human mixing patterns relevant to infectious diseases spread through close contact is vital for modelling transmission dynamics and optimisation of disease control strategies. Mixing in low-income countries like Malawi are not well understood. Methodology We conducted a social survey urban Blantyre, between April July 2021 (between the 2nd 3rd wave COVID-19 infections). Participants living densely-populated neighbourhoods were randomly sampled and, if they...
<ns3:p>Background The COVID-19 epidemic in Malawi involved almost 90,000 recorded cases and 2,638 deaths. Data suggest that the developed largely urban settings, but extent of rural spread – exposing older adults particular is unclear. This concern led us, to develop ‘Kuteteza’ partnership project: a community-based Public Health intervention involving shielding additional strategies mitigate impacts Malawi. We now present results realist project evaluation. Methods Clinicians,...
<ns3:p>Background The COVID-19 epidemic in Malawi involved almost 90,000 recorded cases and 2,638 deaths. In response to early concerns about vulnerable older people rural areas, we developed ‘Kuteteza’: a mitigation project. Clinicians, public health professionals, researchers collaborated with government district-level staff two Southern districts. Interventions included supported ‘shielding’ of – minimising social mixing whilst having their daily needs supported. Additional strategies...