A5046625682- Nanoparticles: synthesis and applications
- Advancements in Transdermal Drug Delivery
- Genetics, Aging, and Longevity in Model Organisms
- Ginger and Zingiberaceae research
- Enzyme Catalysis and Immobilization
- Effects and risks of endocrine disrupting chemicals
- Lipid Membrane Structure and Behavior
- Chromatography in Natural Products
- Chemical Safety and Risk Management
- Nanotechnology research and applications
- Biotechnology and Related Fields
- Analytical Methods in Pharmaceuticals
- Phytochemistry Medicinal Plant Applications
- Carcinogens and Genotoxicity Assessment
- Advanced Photocatalysis Techniques
- Advanced Drug Delivery Systems
- biodegradable polymer synthesis and properties
- Selenium in Biological Systems
- Analytical Chemistry and Chromatography
- Organoselenium and organotellurium chemistry
- Insect and Pesticide Research
- Genomics, phytochemicals, and oxidative stress
- TiO2 Photocatalysis and Solar Cells
- Microencapsulation and Drying Processes
- Graphene and Nanomaterials Applications
Universidade Federal do Rio Grande do Sul
2023-2024
Universidade Federal do Pampa
2019-2024
Universidade Federal de Santa Maria
2023-2024
The Purple Pitanga Extract (PPE) demonstrated apoptotic and anti-cancer effects in previous studies with cells. Therefore, the investigation of specific pathways involved development cancer using vivo models is necessary. objective this study was to evaluate safety efficacy PPE PP-loaded liposomes (PPL) Caenorhabditis elegans (C. elegans) that develop multivulva (Muv) phenotype caused by gain function let-60 (gf), a homologous human Ras. Treatment for 48h up 100 μg CAE/mL safe mutant worms...
Abstract In this study, we evaluated the toxicological and antiproliferative effects of B. glabra Choisy bract extract (BGCE) in its free loaded into liposomes forms administered to C. elegans mutants with let‐60 gain‐of‐function ( gf ). Our results demonstrated that concentration up 75 μg CAE/mL BGCE was safe for worms. Notably, developed BGCE‐loaded extend pharmacological window 100 without toxicity. addition, reduced number area multivulva formed mutants. There also an increase apoptotic...
This study aimed to develop and validate an analytical methodology based on derivative spectrophotometry determine the true concentration of ginger (ZEO) rosemary (REO) essential oils in nanocapsule redispersible powder formulations. Second-order made it possible nullify interference components at 240 245 nm wavelengths for ZEO REO, respectively. The validated method was linear range 0.01-0.04 mg mL−1 0.6-0.96 REO. It is also accurate with RSD 1.82 1.44 REO respectively, shows recovery rates...
Development and validation of high-performance liquid chromatography method
Abstract Cardiovascular diseases are one of the major causes deaths around world. The leading cause is related to high cholesterol levels, therefore, controlling these levels has been a successful strategy. Among drugs used for this purpose, atorvastatin (ATV) great efficacy, however some side effects reduce patient adhesion. In context, development ATV polymeric nanocapsules co-encapsulated with ginger (NCAtG) or grape seed (NCAtU) oil can toxicity and increase its efficacy. objectives work...