- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Systems and Public Health
- Melanoma and MAPK Pathways
- Public Health and Social Inequalities
- Global Cancer Incidence and Screening
- Pneumonia and Respiratory Infections
- Childhood Cancer Survivors' Quality of Life
- CAR-T cell therapy research
- Complement system in diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Emergency and Acute Care Studies
- Acute Lymphoblastic Leukemia research
- Vasculitis and related conditions
- Healthcare Policy and Management
- Workplace Health and Well-being
- Lymphoma Diagnosis and Treatment
- Hearing, Cochlea, Tinnitus, Genetics
- Primary Care and Health Outcomes
- Testicular diseases and treatments
- Synthesis of Organic Compounds
- Abdominal vascular conditions and treatments
- Chronic Disease Management Strategies
- Integrated Circuits and Semiconductor Failure Analysis
Creighton University
2020-2025
Pneumonia is amongst the leading causes of death in United States. In 2020, pneumonia accounted for over 53,000 deaths and 2.6 million emergency department visits. Further research needed to study evolution country-wide trends disparities. The centers disease control prevention wide-ranging online data epidemiologic (CDC WONDER) was used identify pneumonia-related within States from 1999 2022. Data on demographic regional groups were analyzed by calculating age-adjusted mortality rates...
Hearing loss caused by noise, aging, antibiotics, and chemotherapy affects 10% of the world population, yet there are no Food Drug Administration (FDA)-approved drugs to prevent it. Here, we screened 162 small-molecule kinase-specific inhibitors for reduction cisplatin toxicity in an inner ear cell line identified dabrafenib (TAFINLAR), a BRAF kinase inhibitor FDA-approved cancer treatment. Dabrafenib six additional BRAF/MEK/ERK cellular pathway mitigated cisplatin-induced hair death mouse...
Pediatric Hepatoblastoma is a rare malignancy of the liver. This study used National Cancer Database (NCDB) to identify 1068 patients diagnosed with hepatoblastoma from 2004 2020. χ 2 and Analysis Variance testing, as well Kaplan-Meier, Cox Regression, multinomial logistic regression models were used. Data was analyzed using SPSS version 27, statistical significance set at α=0.05. Our results found Black experienced significantly lower median survival rate compared White patients, difference...
We describe the case of a 19-year-old woman who presented with abdominal pain, vomiting, and palpable purpuric rash. The patient subsequently developed dysentery was found to have an infection from Shiga toxin–producing Escherichia coli. also met diagnostic criteria for IgA vasculitis (also known as Henoch Schönlein purpura) but had negative immunofluorescence biopsies treated steroids achieved recovery. To our knowledge, this is first documented in setting enterohemorrhagic E. coli...
<title>Abstract</title> Background: Pneumonia is the amongst leading causes of death in United States. In 2020, pneumonia accounted for over 53,000 deaths and 2.6 million emergency department visits. Further research needed to study evolution country-wide trends highlight disparities. Methods: Centers Disease Control Prevention Wide-ranging Online Data Epidemiologic Research (CDC WONDER) was used identify pneumonia-related occurring within We extracted data regarding population sizes from...
10062 Background: Hepatoblastoma is the most common malignant liver tumor which affects pediatric patients. However, incidence rare with 100 cases reported per year. 1 Current management consists of surgery and adjuvant cisplatin chemotherapy radiation depending on histology, resectability, metastasis. 2 due to its rarity, optimal treatment protocol remains unclear. The 5-year overall survival rate in US approximately 57-69% . Methods: National Cancer Database (NCDB) was used identify...
Introduction: Prior data report female sex, race, and impoverished populations by income insurance status as less likely to receive atrial fibrillation (AF) ablation. Beyond this disparity, the impact of Social Determinants Health (SocDH) in those that AF ablation clinical outcomes is unknown. Using Health-Related Needs (HRSNs) an indicator SocDH, we assessed hospital readmissions after Methods: The 2010-2019 Nationwide Readmissions Database was queried for ICD-9/10 procedure diagnosis codes...