Parvin Mahzouni

ORCID: 0000-0002-4426-4329
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About
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Research Areas
  • Microscopic Colitis
  • Inflammatory Bowel Disease
  • Glioma Diagnosis and Treatment
  • Gastrointestinal motility and disorders
  • Natural Antidiabetic Agents Studies
  • Meningioma and schwannoma management
  • Neurofibromatosis and Schwannoma Cases
  • Brain Metastases and Treatment
  • Pharmacological Effects of Natural Compounds
  • Drug Solubulity and Delivery Systems
  • Ethnobotanical and Medicinal Plants Studies
  • Neuroblastoma Research and Treatments
  • Essential Oils and Antimicrobial Activity
  • Soft tissue tumor case studies
  • Sarcoma Diagnosis and Treatment
  • Pancreatitis Pathology and Treatment
  • Nuts composition and effects
  • Oral and Maxillofacial Pathology
  • Diet, Metabolism, and Disease
  • Salivary Gland Tumors Diagnosis and Treatment
  • Rabbits: Nutrition, Reproduction, Health
  • Ovarian cancer diagnosis and treatment
  • Testicular diseases and treatments
  • Colorectal and Anal Carcinomas
  • Helicobacter pylori-related gastroenterology studies

Isfahan University of Medical Sciences
2012-2023

Alzahra Medical and Education Center
2007-2012

University of Isfahan
2008-2012

Alzahra University
2008

Marymount University
2006

Walnut is one of the medicinal plants used in traditional Iranian medicine as a treatment for diabetes, but little scientific documentation supports its antidiabetic action. This study designed to evaluate effect ethanolic walnut leaf extract. Twenty-four male Wistar rats were divided into four groups: nondiabetic rats, alloxan-induced diabetic with no treatment, treated extracts Juglans regia (200 mg/kg), and glibenclamide (0.6 mg/kg). Fasting blood sugar decreased meaningfully J....

10.1089/jmf.2007.0611 article EN Journal of Medicinal Food 2008-09-01

An oral colon-targeted formulation of budesonide was developed for treatment ulcerative colitis. Budesonide conjugates were prepared using glutarate spacer and different molecular weights (MW) dextran their degree substitution (DS), solubility, stability examined. Drug release in the presence rat colonic contents studied. In vivo efficacy studied against acetic-acid induced colitis rat. DS dependent on polymer MW 7.40 ± 0.18, 5.20 0.35, 13.80 0.48 mg/100 mg conjugate 10,000, 70,000, 500,000,...

10.3109/10611861003801826 article EN Journal of drug targeting 2010-04-30

The aim of this study was developing colon targeted-delivery budesonide for ulcerative colitis. Microcapsules were prepared using spray drying technique by different drug-to-dextran ratios and three molecular weights (MWs) polymer. Differential scanning calorimetry, X-ray diffraction (XRD), drug release loading efficiency microcapsules studied. In vivo efficacy the selected formulation 1 : 10 drug-to-polymer ratio dextran with MW 500 000 (D10M500) against acetic acid-induced colitis in rats...

10.3109/02652048.2010.529947 article EN Journal of Microencapsulation 2010-12-20

Acute pancreatitis is a morbid inflammatory condition of pancreas with limited specific therapy. Enhanced oxidative stress plays an important role in induction and progression acute pancreatitis. So reducing may relieve this pathogenic process. Echium amoenum Fisch. Mey has been implemented Iranian folk medicine for several centuries. Antioxidant, analgesic, immunomodulatory, anxiolytic properties E. suggest that plant have beneficial effects the management The aim study was to evaluate...

10.5402/2012/141548 article EN ISRN Gastroenterology 2012-09-13

There is a pressing need for research leading to the development of new effective drugs with lower side effects and more efficacy treating inflammatory bowel disease (IBD). The analgesic anti-inflammatory properties 5-Hydroxytryptamine (5-HT)-3 receptor antagonists have been shown in vivo vitro studies. present study was designed investigate tropisetron, 5-HT3 antagonist, on an immune-based animal model IBD.In study, trinitrobenzenesulfonic acid (TNBS) colitis rat used. Two hours after...

10.5681/bi.2013.021 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2013-01-01

Coronary artery disease (CAD), which is a multi-factorial frequently, causes morbidity and mortality in human beings. Scientists now believe that there good link between the inflammatory process coronary atherosclerosis. A study was conducted to find out anti- atherosclerosis effect of Amaranthus caudatus L. on rabbits, compared with lovastatin. Twenty five male New Zealand rabbits were randomly grouped into each fed for 60 days with  standard diet, diet cholesterol, and  A. extract (150...

10.5897/jmpr09.198 article EN Journal of Medicinal Plants Research 2010-03-04

Astrocytic brain tumors are the most common primary central nervous system tumors, which classified into four grades. One of important pathologic criteria for diagnosis higher-grade astrocytomas (especially glioblastoma multiforme) is microvessel proliferation, particularly in form glomeruloid complex. Because tumor angiogenesis a necessary factor growth and invasiveness malignancies, density (MVD) intensity may be used to determine grade plan therapy accordingly. We have planned this study...

10.4103/0377-4929.71996 article EN cc-by-nc-sa Indian Journal of Pathology and Microbiology 2010-01-01

Immuonohistochemically images of meningioma which are stained by ki67 marker contain positive and negative cells. Accurate counting the number cells in such play a critical role diagnosing different type cancer. Since pathological complex cell cluster accurate methodology is major challenge for pathologist physicians. In this paper we provide computer aided algorithm detecting proliferative mitosis index immunohistochemically meningioma. first stage fuzzy c-means clustering was used to...

10.1109/iranianmvip.2010.5941151 article EN 2010-10-01
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