A5012168271- Phytochemicals and Antioxidant Activities
- Phytochemical compounds biological activities
- Phytochemistry and biological activity of medicinal plants
- Phytochemistry and Bioactivity Studies
- Essential Oils and Antimicrobial Activity
- Histone Deacetylase Inhibitors Research
- Cannabis and Cannabinoid Research
- Natural product bioactivities and synthesis
- Computational Drug Discovery Methods
- Piperaceae Chemical and Biological Studies
- Coconut Research and Applications
- Bee Products Chemical Analysis
- Natural Antidiabetic Agents Studies
- Plant chemical constituents analysis
- GABA and Rice Research
- melanin and skin pigmentation
- Phytochemistry and Biological Activities
- Seaweed-derived Bioactive Compounds
- Phytochemistry Medicinal Plant Applications
Pokhara University
2023-2025
Ethnomedicinally, more than 2000 plants were found to be used in Nepal. Among them, the red colored rhizome of Angiopteris helferiana and bark Saurauia fasciculata have been widely treat muscle fatigue, bone pain, fever, postpartum hemorrhage, thirst by healers Kaski Tanahun districts, However, scientific evidence towards their traditional uses is lacking till December, 2023. Therefore, we report phytochemicals, total phenolic content (TPC), flavonoid (TFC), carbohydrate (TCC), antioxidant...
Background Crateva unilocularis, Millettia extensa, and Plumbago zeylanica are commonly used traditional medicinal plants in Nepal for treating various skin ailments. Objectives The ethanol extracts of these were analyzed qualitative quantitative phytochemical content, antioxidant potential, anti-tyrosinase activity. Methods Folin-Ciocalteu technique was to measure the total phenolic aluminum chloride method assess flavonoid content.In vitro activity evaluated via 2,2-...
Article Exploring the Therapeutic Promise of Drynaria Coronans: Phytochemical Analysis, Antioxidant Capacity, α-Amylase Inhibition with Safety Assessment Prabhat Kumar Jha 1,2,*, Sindhu KC 1, Ram Kishor Yadav Bipindra Pandey 2, Sandesh Paudel Ravindra Khadka Kushal Subedi Sushil Panta 1,* 1 School Health and Allied Sciences, Pokhara University, Kaski 33700, Nepal 2 Department Pharmacy, Madan Bhandari Academy Hetauda 44100, * Correspondence: jha.prabhat9999@gmail.com.com (P.K.J.);...
Jumli Marshi (J. Marshi) , a native rice cultivar in Nepal, is gaining popularity owing to its health benefits for obesity, hypertension, and diabetes. However, scientific evidence verifying therapeutic potential lacking until November 2024. Therefore, we aimed characterize the phytoconstituents evaluate antioxidant, antibacterial, antidiabetic properties of J. Marshi, along with ADME toxicity profile, using both vitro silico approaches. Liquid chromatography-mass spectrometry analysis 70%...
Background: Falconeria insignis Royle, a medicinal plant of the Euphorbiaceae family, has been extensively used in Nepal for bacteria-infected wounds, despite lack empirical evidence supporting its efficacy. Objectives: This study aims to evaluate phytopharmaceutical potential F. leaves and stems combating oxidative stress bacterial infections. Methods: Phytoconstituents were characterized using LC-MS technique. The antioxidant activity was evaluated through DPPH, nitric oxide, hydroxyl...
Liver cancer is one of the most prevalent malignant diseases in humans and second leading cause cancer-related mortality globally. Angiopteris helferiana was mentioned as a possible anticancer herb according to ethnomedicinal applications. However, molecular docking chemical profiling bioactive phytoconstituents accountable for reported action still require research. The present study aims phytochemical bioactivity evaluation A . design with in-vitro in-silico technique LC-MS followed by...
Objective: Nepal's medicinal herbs are rich in cultural importance and have several uses. Senna alata, a plant belonging to the Leguminosae family, is prized for its aesthetic therapeutic qualities. The goal of study was extract alata leaves using solvent macerations. Methods: aims evaluate phytochemistry, total phenolic flavonoid levels, antioxidant qualities vitro, anti-inflammatory effects, cytotoxicity, anti-thrombolytic potential, antibacterial activity, variety methodologies were...
The unique historical and cultural background of Nepal has shaped its perspective on cannabis usage. Narcotic Drugs Control Act 1976 prohibits the cultivation, production, manufacture, sales, distribution narcotic drugs, which also include various forms cannabis. With proponents for legalization increasing in country, it is equally crucial to analyze context practices countries already adopting legalization. As such, this article contextualizes current debates with global policies talks...
Objective . The red rhizome of Angiopteris helferiana has been used widely to treat muscle fatigue, bone pain, and skin infection in Nepal. However, scientific evidence for its bioactive compounds their bioactivities was lacking till January, 2024. Therefore, we investigated validate advance the further use development. Methods Column chromatography, including MCI gel CHP20P, Sephadex LH‐20, ODS, Silica gel, isolation from 70% methanol extract A. rhizomes. isolated were evaluated TLC‐based...
Background: Fever, characterized by an elevated body temperature beyond the normal range, necessitates effective management. Traditional therapies rooted in indigenous knowledge prove effective, addressing fever-related conditions for optimal well-being. This study explores antipyretic potential of Murraya koenigii, a plant deeply traditional practices Nepal. Materials and Methods: The hydroethanol leaf extract koenigii was subjected to phytochemical screening acute toxicity assessment,...
Aim: Nepal’s medicinal plants are culturally important and have diverse benefits. Senna alata belongs to the family Leguminosae is a valuable plant utilized for ornamental purposes. The aim of research was extract leaves by successive maceration with various solvents. Methods: In this study, methods were evaluate phytochemistry, overall phenolic flavonoid content, in-vitro antioxidant, anti-inflammatory, cytotoxicity assay, anti-thrombolytic activity, antibacterial activities. Results:...