A5029025561- Neuroblastoma Research and Treatments
- Eosinophilic Esophagitis
- Gastrointestinal motility and disorders
- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Congenital gastrointestinal and neural anomalies
- Adrenal and Paraganglionic Tumors
- Neuroendocrine Tumor Research Advances
- Infant Health and Development
- Foreign Body Medical Cases
- Pharmaceutical studies and practices
- Sarcoma Diagnosis and Treatment
- Simulation-Based Education in Healthcare
- Child and Adolescent Health
- IgG4-Related and Inflammatory Diseases
- Breastfeeding Practices and Influences
- Restraint-Related Deaths
- Neurofibromatosis and Schwannoma Cases
- Architecture, Design, and Social History
- Innovations in Medical Education
- Neurogenesis and neuroplasticity mechanisms
- Gastrointestinal disorders and treatments
- Medical Malpractice and Liability Issues
- Pediatric Pain Management Techniques
- Pancreatitis Pathology and Treatment
Walter Reed National Military Medical Center
2020-2024
Uniformed Services University of the Health Sciences
2020-2024
RELX Group (United States)
2023
Bellevue Hospital Center
2021
Baylor College of Medicine
2021
Naval Medical Center Portsmouth
2017
Cincinnati Children's Hospital Medical Center
2011
Massachusetts General Hospital
2011
University of Cincinnati
2011
Abstract Plexiform neurofibromas are peripheral nerve sheath tumors initiated by biallelic mutation of the NF1 tumor suppressor gene in Schwann cell lineage. To understand whether neurofibroma formation is possible after birth, we induced Nf1 loss function with an inducible proteolipid protein Cre allele. Perinatal resulted development small plexiform late life, whereas adulthood caused large and morbidity beginning 4 months onset loss. A conditional EGFP reporter allele identified cells...
Abstract A 2023 product recall has described the risk for morbidity and mortality children ingesting water beads. We aimed to describe bead exposure management trends in United States. used National Electronic Injury Surveillance System (NEISS) identify injuries from 2013 2023. Inclusion criteria were ages 0–17 years, diagnosis of ingested object/foreign body, narrative word(s) suggested bead(s). NEISS supplied weights variance variables generate national estimates. There 226 (66%...
Eosinophilic esophagitis (EoE) disease activity can be caused by treatment non-adherence. Medication possession ratio (MPR) is an established metric of medication adherence. A higher MPR correlates with better outcomes in several chronic diseases, but has not been investigated respect to EoE. retrospective cohort study was performed using EoE registry for the years 2005 2020. Treatment periods were identified, MPRs calculated, and medical records assessed histologic remission (<15...
Type 2 autoimmune pancreatitis, an increasingly recognized etiology of pancreatitis in patients less than 20 years old, has characteristically been diagnosed with the histological finding duct-centric a patient who lacks elevated serum immunoglobulin G4. We present case nonobese 15-year-old male, without any chronic medical conditions, presented chief complaint abdominal pain. The laboratory study results were remarkable for lipase level 5,419 U/L and γ-glutamyl transferase 373 U/L. Magnetic...
Functional constipation (FC) comprises 30% of pediatric gastroenterology clinic visits. FC results from withholding behaviors that can be worsened by poor toileting posture. The use a defecation posture modification device (DPMD)—a potty stool—has demonstrated benefit in adults. aim this study was to assess the risks and benefits incorporating DPMD as an adjunct treatment plan for children. Toilet-trained children aged ≥4 years meeting Rome IV criteria were enrolled offered at no cost...
Objective Functional gastrointestinal disorders account for a large burden of disease in children. Specifically, constipation tends to comprise 25% or more visits Pediatric Gastroenterologists. With the publication ROME IV criteria, recognition functional (FC) as process has become refined, yet pharmacotherapy and lifestyle modifications management children with FC have remained fairly static. Our aim was conceptualize, design, validate an evidence-based, personalized action plan pictograms...
Supplementary Figure 2 from Perinatal or Adult <i>Nf1</i> Inactivation Using Tamoxifen-Inducible <i>PlpCre</i> Each Cause Neurofibroma Formation
Supplementary Figure 2 from Perinatal or Adult <i>Nf1</i> Inactivation Using Tamoxifen-Inducible <i>PlpCre</i> Each Cause Neurofibroma Formation
Supplementary Legends for Figures 1-2, Table 1 from Perinatal or Adult <i>Nf1</i> Inactivation Using Tamoxifen-Inducible <i>PlpCre</i> Each Cause Neurofibroma Formation
Supplementary Figure 1 from Perinatal or Adult <i>Nf1</i> Inactivation Using Tamoxifen-Inducible <i>PlpCre</i> Each Cause Neurofibroma Formation
Supplementary Legends for Figures 1-2, Table 1 from Perinatal or Adult <i>Nf1</i> Inactivation Using Tamoxifen-Inducible <i>PlpCre</i> Each Cause Neurofibroma Formation
Supplementary Figure 1 from Perinatal or Adult <i>Nf1</i> Inactivation Using Tamoxifen-Inducible <i>PlpCre</i> Each Cause Neurofibroma Formation
<div>Abstract<p>Plexiform neurofibromas are peripheral nerve sheath tumors initiated by biallelic mutation of the NF1 tumor suppressor gene in Schwann cell lineage. To understand whether neurofibroma formation is possible after birth, we induced <i>Nf1</i> loss function with an inducible proteolipid protein Cre allele. Perinatal resulted development small plexiform late life, whereas adulthood caused large and morbidity beginning 4 months onset loss. A conditional...
<div>Abstract<p>Plexiform neurofibromas are peripheral nerve sheath tumors initiated by biallelic mutation of the NF1 tumor suppressor gene in Schwann cell lineage. To understand whether neurofibroma formation is possible after birth, we induced <i>Nf1</i> loss function with an inducible proteolipid protein Cre allele. Perinatal resulted development small plexiform late life, whereas adulthood caused large and morbidity beginning 4 months onset loss. A conditional...
Clinical clerkship curricula should exist to provide rotating learners on subspecialty rotations with consistent exposure specific topics geared toward the discipline of interest, such as pediatric gastroenterology (GI). We aim describe our experience developing and implementing DIGEST: Digital Interactive Gastroenterology Education Suite for Trainees, a novel, online GI curriculum delivered virtual, during coronavirus (COVID-19) pandemic stay-at-home order.A general needs assessment in 2019...