A5082648825- Meningioma and schwannoma management
- Head and Neck Surgical Oncology
- Folate and B Vitamins Research
- Global Health Workforce Issues
- Metabolism and Genetic Disorders
- Trace Elements in Health
- Neurofibromatosis and Schwannoma Cases
- Bone Tumor Diagnosis and Treatments
- Ear and Head Tumors
- Global Health and Surgery
- Diversity and Career in Medicine
- Blood Coagulation and Thrombosis Mechanisms
- Abdominal Trauma and Injuries
- Spinal Fractures and Fixation Techniques
- Musculoskeletal synovial abnormalities and treatments
- Retirement, Disability, and Employment
- Pregnancy and Medication Impact
- Vestibular and auditory disorders
- Streptococcal Infections and Treatments
- Pituitary Gland Disorders and Treatments
- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Acute Ischemic Stroke Management
- Cerebral Palsy and Movement Disorders
- Cerebrospinal fluid and hydrocephalus
SUNY Downstate Health Sciences University
2024
University of Louisville
2016-2022
Neurological Surgery
2020-2022
Loyola University Chicago
2022
Loyola University Medical Center
2022
University of Louisville Hospital
2020-2021
University of California, San Francisco
2020-2021
Kosair Children's Hospital
2021
University of Washington
2020
Seattle University
2020
Glycerol rhizotomy was originally described as an initial surgical treatment for trigeminal neuralgia after the failure of medical therapy. Here we describe its use a salvage procedure, typically multiple other modalities including microvascular decompression, stereotactic radiosurgery, and/or percutaneous procedures. Foramen ovale cannulation “salvage procedure” may be complicated by lack cerebrospinal fluid (CSF) return despite adequate foramen ovale, making conventional fluoroscopic...
The objective of this study is to further patient-physician discussion regarding postoperative quality life expectations after surgical acoustic neuroma resection.This retrospective prospective. Qualifying patients were identified and administered Penn Acoustic Neuroma Quality-of-Life (PANQOL) Scale.The setting was Loyola University Chicago Health System.Three hundred twenty-six at our center with surgically resected between January 1990 July 2021 completed the PANQOL.During postresection...
Tenosynovial giant cell tumor (TGCT) is a rare entity that not well described in the neurosurgical literature. We present case of 37-year-old woman with diffuse subtype TGCT cervical spine, affecting left 6-7 facet joint, co-incidental trauma. Initial management consisted subtotal resection and stabilization 6 to 7 laminectomy, 4 thoracic 2 posterior instrumented fusion. Gross total was achieved at later date plan for postoperative radiation prevent recurrence. The patient lost follow-up...
Abstract Objective The evolution of acoustic neuroma (AN) care continues to shift focus on balancing optimized tumor resection and control with preservation neurological function. Prior learning curve analyses AN have demonstrated a plateau between 20 100 surgeries. In this study 860 consecutive surgeries, we investigate the presence an extended tail for resection. Methods A retrospective cohort resections by single interdisciplinary team 1988 2018 was performed. Proportional odds models...
OBJECTIVE Advancements in microsurgical technique and technology continue to improve outcomes patients with skull base tumor. The primary cranial nerve eight monitoring systems used hearing preservation surgery for vestibular schwannomas (VSs) are direct (DCNEM) auditory brainstem response (ABR), although current guidelines unable definitively recommend one over the other due limited literature on topic. Thus, further research is needed determine utility of DCNEM ABR. authors performed a...
Introduction The petroclival region is an integral part of the skull base. It can harbor different pathologies and provides access to junction cerebellopontine angle. We present results morphometric analysis posterior fossa a prediction model enable base surgeons choose optimal surgical corridor considering patient's bony anatomy. Methods Ninety patients (14 assess interobserver reliability) with temporal bone computed tomography were selected. Exclusion criteria included <18 years age,...
Primary encephaloceles (PEs) present only rarely in the temporal region; rare instance that they project through floor of middle fossa are secondary. In this case report authors on management a giant PE extending fossa.An 8-month-old boy presented to authors' service with large projecting into his neck missing left floor; lesion was causing significant meta-, dys-, and hypoplasia structures anterolateral side. Surgical goals for patient included following: 1) removal potentially...
Posterior vault distraction osteogenesis (DO) is an emerging treatment option for craniosynostosis. Operative nuances detailing surgical management are being described with increasing use and experience. In this article, we discuss the of 8-month-old male a ventriculoperitoneal shunt (VPS) diagnosed bilateral lambdoid craniosynostosis Chiari I malformation. The patient underwent successful posterior fossa DO without re-implantation shunt. Pre- post-operative imaging confirmed no migration...
Hypermethylation of the genes silence transcriptions functional associated to cognitive functions. Loss memory due epigenetic modifications, called memory-epigenetics was studied. Netrin is a glycoprotein involved in neurogenesis, axonal guidance and maintenance synaptic plasticity. We hypothesized that high methionine-low vitamins containing diet leads impairment by increasing global DNA methylation therefore, silencing netrin gene. Wild type (C57BL/6J) mice were fed excess met (1.2%),...
Methionine is an amino acid found in rich quantities proteinaceous foods such as meats, fish and eggs. This essential high the average American diet due to protein consumption that far exceeds daily requirement. Besides previous studies showing a correlation between methionine osteoporosis, heart attacks pregnancy complications, more recent are links neurodegenerative disorders Alzheimer's dementia. However, mechanisms of methionine's effects not clear. Therefore, this study focused on...
Plasminogen activator inhibitor type I (PAI-1) is important for balancing the fibrinolytic effect of plasmin, and deficiency can result in increased risk bleeding. We report a case patient with PAI-1 who presented delayed spontaneous recurrence an acute subdural hematoma (aSDH) after evacuation.A 29-year-old male altered mental status (AMS) fall at construction site Glasgow Coma Scale (GCS 4T). His coagulation profile was normal, brain computed tomography (CT) showed left-sided aSDH. He...
Chandra, Ankush MS; Brandel, Michael G MD, MAS; Wadhwa, Harsh; Pereira, Matheus P; Lewis, Cole T MD; Haddad, Yazeed; Lu, Victor M MBBS, MPhil, MS, PhD; Almeida, Neil; Nuru, Mohammed; Spatz, Jordan Aghi, Manish K PhD Author Information
Abstract Introduction The transcribriform and transclival corridors are endoscopic endonasal approaches used to treat pathologies of the skull base. We present a predictive model that uses clival length ethmoidal width predict size surgical freedom (SF) these corridors. Methods Adult facial computed tomography scans were reviewed. Exclusion criteria included patients <18 years age or radiographic evidence trauma, neoplasm, congenital deformities images analyzed using OsiriX MD (Bernex,...