Isabel Coloma

ORCID: 0000-0002-4969-9479
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About
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Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Molecular Junctions and Nanostructures
  • Force Microscopy Techniques and Applications
  • Metal complexes synthesis and properties
  • Organometallic Complex Synthesis and Catalysis
  • Mechanical and Optical Resonators
  • Organometallic Compounds Synthesis and Characterization
  • Advanced Materials Characterization Techniques
  • Photosynthetic Processes and Mechanisms
  • Ferrocene Chemistry and Applications
  • Coordination Chemistry and Organometallics
  • Synthesis and Properties of Aromatic Compounds
  • Plant nutrient uptake and metabolism
  • Magnetism in coordination complexes
  • Mesoporous Materials and Catalysis
  • Metalloenzymes and iron-sulfur proteins
  • Carbon Nanotubes in Composites
  • Crystallography and molecular interactions
  • Free Radicals and Antioxidants
  • Lanthanide and Transition Metal Complexes
  • Click Chemistry and Applications
  • Catalysis and Oxidation Reactions

Universidad Complutense de Madrid
2020-2025

Drug resistance, one of the main drawbacks in cancer chemotherapy, can be tackled by employing a combination drugs that target different biological processes cell, enhancing therapeutic efficacy. Herein, we report synthesis and characterization new paddlewheel diruthenium complex includes 5-fluorouracil (5-FU), commonly used anticancer drug. This drug was functionalized with carboxylate group to take advantage previously demonstrated release capacity ligands from core. The resulting...

10.1021/acs.inorgchem.4c01323 article EN cc-by Inorganic Chemistry 2024-06-04

We report the preparation of a helical complex and its study in molecular junctions. show that SAMs this racemic compound present electrically robust behaviour which will pave way for future studies on CISS effect with analogous enantiopure compounds.

10.1039/d5nr00050e article EN cc-by Nanoscale 2025-01-01

The study of the release carboxylate ligands from diruthenium compounds is crucial for designing drug delivery systems based on such complexes. influence different key parameters process was evaluated through in vivo assays.

10.1039/d3qi00399j article EN cc-by Inorganic Chemistry Frontiers 2023-01-01

The controlled release of functionally active compounds is important in a variety applications. Here, we have synthesized, characterized, and studied the magnetic properties three novel metal-metal-bonded tris(formamidinato) Ru25+ complexes. We used different auxin-related hormones, indole-3-acetate (IAA), 2,4-dichlorophenoxyacetate (2,4-D), 1-naphthaleneacetate (NAA), to generate [Ru2Cl(μ-DPhF)3(μ-IAA)] (RuIAA), [Ru2Cl(μ-DPhF)3(μ-2,4-D)] (Ru2,4-D), [Ru2Cl(μ-DPhF)3(μ-NAA)] (RuNAA) (DPhF =...

10.1021/acs.inorgchem.0c00844 article EN Inorganic Chemistry 2020-05-15

This work presents an axially chiral platform based on ruthenium units, evaluates the crystal structures, configurational stability and electronic structure tunability, proposes a general nomenclature system for binuclear paddlewheel complexes.

10.1039/d4ce01040j article EN cc-by-nc CrystEngComm 2024-01-01
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