A5065134806- Hormonal Regulation and Hypertension
- Menopause: Health Impacts and Treatments
- Estrogen and related hormone effects
- Nitric Oxide and Endothelin Effects
- Education Pedagogy and Practices
- Peroxisome Proliferator-Activated Receptors
- Birth, Development, and Health
- Venomous Animal Envenomation and Studies
- Diet, Metabolism, and Disease
- Inflammatory mediators and NSAID effects
- Bone health and osteoporosis research
- Pharmacology and Obesity Treatment
- Healthcare and Venom Research
- Phytoestrogen effects and research
- Diet and metabolism studies
- Sodium Intake and Health
- Hormonal and reproductive studies
- Science and Education Research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Liver Disease Diagnosis and Treatment
- Bone health and treatments
- Emotional Intelligence and Performance
- Pain Mechanisms and Treatments
- Health, Education, and Physical Culture
- Nutritional Studies and Diet
Universidade Federal do Espírito Santo
2017-2025
Abstract Women in postmenopausal period may present several comorbidities linked to metabolic syndrome (MetS). Our hypothesis is that kefir prevent the deleterious effects renal function an experimental model of (MetS) and ovarian hormone deficiency. Young female spontaneously hypertensive rats (SHR) were divided into four groups: ovariectomized (OVX) control, OVX fructose, kefir, + fructose. They received (5% w/v) via gavage for 8 weeks, while fructose (10% was available ad libitum. In...
The action of oestrogen has traditionally been attributed to the activation nuclear receptors (ERα and ERβ). A third receptor, G protein-coupled receptor (GPER), described as mediator rapid oestrogen. Based on possible protective role in cardiovascular system, present study was designed determine whether selective GPER induces relaxation mesenteric resistance arteries both sexes which signalling pathways are involved.Third-order were isolated, concentration-response curves plotted following...
ABSTRACT 8‐Prenylnaringenin (8‐PN) is one of the most potent phytoestrogens identified to date. Despite its role as an estrogen receptor modulator and vast therapeutic potential, effects this molecule on brain behavior females remain largely unexplored. This study hypothesized that 8‐PN exerts cognitive by preventing oxidative damage in promoting expression neurotrophins. Female mice were divided into five groups received acute treatments with LPS (1 mg/kg), or 2 a combination doses, vehicle...
Background: Endothelial dysfunction is commonly present in estrogen-deficient states, e.g., after menopause. In the search for alternatives to hormone replacement therapy (HRT), treatments based on phytoestrogens or non-hormonal mechanisms have been under evaluation. Objective: Here we aim an overview of innovative potential endothelial introducing our own preliminary data about probiotic kefir. Methods: We conducted a review PubMed database keywords interest (Menopause, Ovariectomy,...
Functional foods such as probiotics are known to have benefits in various diseases including metabolic disorders and cardiovascular disease (CVD). In women, CVD has been shown be linked with their gut microbiota hormones. Here, we evaluated the effects of chronic Kefir, a fermented milk beverage Russia, Central Asia, Middle East Eastern Europe, on mesenteric artery, using an animal model menopause focusing superoxide anion COX2 pathways. Two-month-old female Wistar rats were ovariectomized...
Glucagon-like peptide-1 (GLP-1) receptor agonists exhibit beneficial cardiovascular effects. However, the renal effects of different doses liraglutide in an essential hypertension model have not yet been investigated. SHR female rats were treated for 30 days, twice a day, with saline (control) or at low (0.06 mg/kg, LL) and high (0.6 LH) doses. Volume intake excretion monitored period 24h. In tissue, nitrite-NO2-, nitrate-NO3-, advanced protein oxidation products-AOPP, collagen deposition,...