A5102969798- Cancer Genomics and Diagnostics
- Genomics and Rare Diseases
- Biomedical Text Mining and Ontologies
- Wikis in Education and Collaboration
- Lung Cancer Treatments and Mutations
- Acute Myeloid Leukemia Research
- Radiomics and Machine Learning in Medical Imaging
- Epigenetics and DNA Methylation
La Roche College
2021
Given the increase in genomic testing routine clinical use, there is a growing need for digital technology solutions to assist pathologists, oncologists, and researchers translating variant calls into actionable knowledge personalize patient management plans. In this article, we discuss challenges facing molecular geneticists medical oncologists working with test results from next-generation sequencing somatic oncology, propose key considerations implementing decision support software aid...
e14072 Background: Evolving medical guidelines and complex multi-variant data from next-generation sequencing (NGS) testing of cancer samples make routine clinical interpretation somatic variants challenging. We assessed the ability NAVIFY(R) Mutation Profiler*, a CE-IVD variant tool, to yield accurate time- geography-specific content on 2511 The Cancer Genome Atlas (TCGA) across six solid tumor types. Methods: Whole exomes lung adenocarcinoma (n = 469), squamous cell carcinoma 325), colon...