A5031007212- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Hemodynamic Monitoring and Therapy
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Ultrasound in Clinical Applications
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Venous Thromboembolism Diagnosis and Management
- Congenital Heart Disease Studies
- Global Public Health Policies and Epidemiology
- Acute Myocardial Infarction Research
- Cardiac Ischemia and Reperfusion
- Health Systems, Economic Evaluations, Quality of Life
- Parathyroid Disorders and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Infective Endocarditis Diagnosis and Management
- Long-Term Effects of COVID-19
- Transplantation: Methods and Outcomes
- Heart Rate Variability and Autonomic Control
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
University of Utah
2014-2025
Intermountain Medical Center
2017-2024
LDS Hospital
2017-2022
Intermountain Healthcare
2022
George E. Wahlen Department of VA Medical Center
2021
British Cardiovascular Intervention Society
2021
University of Utah Hospital
2020
University of Utah Health Care
2019
Background Multidisciplinary teams and regionalized care systems have been suggested to improve cardiogenic shock (CS) outcomes. We sought identify clinical factors associated with successful outcomes for patients developing CS at an outside healthcare facility (spoke) being transferred a quaternary medical center (hub). Methods Results Consecutive were evaluated (N=1162). Our study cohort comprised 412 spoke. primary end point was native heart survival (NHS) defined as discharge without...
Importance The existing models predicting right ventricular failure (RVF) after durable left assist device (LVAD) support might be limited, partly due to lack of external validation, marginal predictive power, and absence intraoperative characteristics. Objective To derive validate a risk model predict RVF LVAD implantation. Design, Setting, Participants This was hybrid prospective-retrospective multicenter cohort study conducted from April 2008 July 2019 patients with advanced heart (HF)...
Extensive evidence from single-center studies indicates that a subset of patients with chronic advanced heart failure (HF) undergoing left ventricular assist device (LVAD) support show significantly improved function and reverse structural remodeling (ie, termed "responders"). Furthermore, we recently published multicenter prospective study, RESTAGE-HF (Remission Stage D Heart Failure), demonstrating LVAD combined standard HF medications induced remarkable cardiac functional improvement,...
Cardiogenic shock (CS) mortality remains near 40%. In addition to inadequate cardiac output, patients with severe CS may exhibit vasodilation. We aimed examine the prevalence and consequences of vasodilation in CS.
Assessment of volume status through the estimation central venous pressure (CVP) is integral in care heart failure (HF). Bedside assessment limited by obesity, variation physical examination skills, and expertise ultrasonography.To validate accuracy quantitative qualitative point-of-care ultrasonography jugular (JVP) predicting elevated CVP.Prospective observational study using convenience sampling.2 U.S. academic hospitals.Adult patients undergoing right catheterization between 5 February...
Background Recent prospective multicenter data from patients with advanced heart failure demonstrated that left ventricular assist device (LVAD) support combined standard medications, induced significant cardiac structural and functional improvement, leading to high rates of LVAD weaning in selected patients. We investigated whether preintervention myocardial systemic inflammatory burden could help identify the subset prone LVAD‐mediated improvement guide patient selection, treatment,...
Abstract Background Methamphetamine is increasingly recognized as a cause of pulmonary arterial hypertension (PAH). This study examines whether non‐invasively measured metrics right heart function, atrial (RA) and ventricular (RV) strain, are more impaired in methamphetamine‐associated PAH (MA‐PAH) compared with idiopathic (IPAH). Methods A retrospective cohort analysis 51 patients MA‐PAH matched for mean artery pressure (mPAP) IPAH followed at the clinic University Utah was performed....
BACKGROUND: The left atrium (LA) maintains a dynamic interaction with the ventricular (LV). LA forward and reverse remodeling affect prognosis in patients chronic heart failure. We examined supported LV assist devices (LVADs) investigated potential impact on clinical outcomes. METHODS: Consecutive advanced failure receiving durable, continuous-flow LVADs were prospectively evaluated (n=263). After excluding unavailable echocardiographic data, 241 studied. Echocardiographic assessment was...
BACKGROUND: Cardiogenic shock (CS) can stem from multiple causes and portends poor prognosis. Prior studies have focused on acute myocardial infarction-CS; however, decompensated heart failure (ADHF)-CS accounts for most cases. We studied patients suffering ADHF-CS to identify clinical factors, early in their trajectory, associated with a higher probability of successful outcomes. METHODS: Consecutive CS were evaluated (N=1162). who developed at our hospital (N=562). Primary end point was...
Background: Cardiac allograft vasculopathy (CAV) remains an important source of mortality after heart transplant. The aim our study was to identify structural and microvasculature changes in severe CAV. Methods Results: group included transplant recipients with CAV who underwent retransplantation (severe CAV, n=20). Control groups time from matched cardiac without (transplant control, n=20), ischemic cardiomyopathy patients requiring left ventricular assist device implantation (ischemic...
BackgroundD2 aortic stenosis (AS) is the highest risk AS subtype with worse operative and mortality outcomes. This study aimed to investigate quality of life (QoL) left ventricular ejection fraction (LVEF) in patients classic (D2 subtype) low-flow/low-gradient who underwent transcatheter valve replacement (TAVR).MethodsIn total, 634 severe TAVR at our institution from 2014 2020, whom 76 met criteria for D2 reduced LVEF. Echocardiographic clinical outcomes including mortality, stroke,...
BACKGROUND: Multidisciplinary Shock Teams have improved clinical outcomes for cardiogenic shock, but their implementation costs not been studied. This study’s objective was to compare between patients treated with and without a Team determine if the team’s is cost-effective compared standard of care. METHODS: We examined refractory shock or at tertiary academic hospital from 2009 2018. Real-world data were used outcomes, including survival discharge, 1-year survival, quality-adjusted life...