A5070024575- Cervical Cancer and HPV Research
- Iron Metabolism and Disorders
- Global Cancer Incidence and Screening
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Urological Disorders and Treatments
- Platelet Disorders and Treatments
- Eosinophilic Disorders and Syndromes
- Trace Elements in Health
- Genital Health and Disease
- Cancer-related molecular mechanisms research
- Molecular Biology Techniques and Applications
- Chronic Myeloid Leukemia Treatments
- Cancer Risks and Factors
- Head and Neck Cancer Studies
- Hemoglobinopathies and Related Disorders
- Polyomavirus and related diseases
Østfold Hospital Trust
2017-2024
Comparative data on different self-collection methods is limited.To assess the impact of hrHPV testing two devices for detection cervical carcinoma and high-grade lesions.Three hundred ten patients collected cervicovaginal specimens using a brush (Evalyn®Brush) swab (FLOQSwabs™), filled questionnaire at home. Then, physician clinic took specimen into PreservCyt® buffer cytology. All were tested Anyplex™ II HPV28, Cobas® 4800 HPV Test Xpert®HPV.Performance comparison included 45 carcinomas...
MicroRNAs (miRNAs) are small non-coding RNAs involved in the regulation of gene expression. Dysregulated expression several miRNAs has been found primary immune thrombocytopenia (ITP) suggesting that likely pathogenesis ITP. We aimed to explore differential patients with ITP before and after starting treatment thrombopoietin-receptor agonists (TPO-RAs) clarify their roles pathophysiology ITP, as potential diagnostic prognostic markers this disorder.We performed a profiling study where 179...
ObjectivesHuman papillomavirus (HPV) infections are common, especially during women's reproductive years, with unclear obstetrical impact. This study aimed to identify HPV prevalence at mid-gestation and delivery, type-specific persistence from risk factors for infection persistence.MethodsIn 757 women a Scandinavian prospective mother–child cohort, was analyzed in first-void urine samples delivery. We used Seegene Anyplex II HPV28 PCR assay genotyping semi-quantifying 28 genital genotypes,...
Knowledge on prevalence and association of human papillomavirus (HPV) in third trimester placentae adverse pregnancy outcomes is limited. We investigated the placental HPV at delivery, explored urine characteristics associated with whether increased risk outcomes.
Abstract Introduction Approximately 25%–43% of all vulvar carcinomas are associated with human papillomavirus (HPV). In many countries, carcinoma incidence rates increasing, possibly due to greater HPV exposure. However, studies exploring changes in prevalence and genotype distribution over time scarce. Our aim was evaluate trends squamous cell an unselected, nationwide sample Norwegian women. Further, we explored clinical histopathological aspects relation status investigated whether...
Abstract Introduction Detection of the JAK 2 V617F mutation is a key step in diagnosis myeloproliferative neoplasms ( MPN ). Sensitive real‐time quantitative PCR qPCR ) detection on peripheral blood PB most widely used method. The main objective this study was to determine whether serum, common material available archival biobanks, good liquid biopsy for detecting and quantifying using droplet digital (dd Methods Paired serum samples from 66 patients with were used. Serum frozen at −25°C...
<b><i>Background:</i></b> Hemochromatosis gene (<i>HFE</i>)-associated hereditary hemochromatosis (HH) is characterized by downregulation of hepcidin synthesis, leading to increased intestinal iron absorption. <b><i>Objectives:</i></b> The objectives were characterize and elucidate a possible association between expression profile, levels, disease severity, markers inflammation in <i>HFE</i>-associated HH patients....