A5023335572- Hereditary Neurological Disorders
- Amyotrophic Lateral Sclerosis Research
- Photovoltaic System Optimization Techniques
- Endoplasmic Reticulum Stress and Disease
- Cellular transport and secretion
- Neurological diseases and metabolism
- Solar Thermal and Photovoltaic Systems
- Toxin Mechanisms and Immunotoxins
- Solar Radiation and Photovoltaics
- Ovarian function and disorders
- RNA Research and Splicing
- Reproductive Biology and Fertility
- Advanced Battery Technologies Research
- solar cell performance optimization
- Hypothalamic control of reproductive hormones
- Cancer-related gene regulation
- Autophagy in Disease and Therapy
Siddhartha Medical College
2024
Brock University
2018
Vellore Institute of Technology University
2014
The T118M mutation in PMP22 gene is associated with Charcot Marie Tooth, type 1A (CMT1A). CMT1A a form of Charcot-Marie-Tooth disease, the most common inherited disorder peripheral nervous system. Mutations CMT related are seen to increase stability protein resulting diseased state. We performed SNP analysis for all nsSNPs and carried out molecular dynamics simulation compare difference between wild structure mutant structure. resulted overall protein. superimposed shows marked structural...
Amyotrophic lateral sclerosis 6 (ALS6) is an autosomal recessive disorder caused by heterozygous mutation in the Fused Sarcoma (FUS) gene. ALS6 a neurodegenerative disorder, which affects upper and lower motor neurons brain spinal cord, resulting fatal paralysis. genetic proline/tyrosine-nuclear localization signals of sarcoma Protein (FUS). FUS gene also known as TLS (Translocated liposarcoma), encodes protein called RNA-binding protein-Fus (FUS), has molecular weight 75 kDa. In this...
The increasing global demand for electricity underscores the need to transition from fossil fuels sustainable alternatives like solar energy. Despite power's advantages of abundance, sustainability, and quiet operation, environmental factors such as temperature irradiance affect efficiency photovoltaic (PV) systems. This study utilizes Perturb Observe (P&O) Maximum Power Point Tracking (MPPT) approach optimize a PV panel, validated through cost-effective Arduino-based hardware model....
Mutations in the gene-encoding vesicle lipopolysaccharide-induced tumor necrosis factor (LITAF) protein cause Charcot–Marie–Tooth type 1C (CMT1C) disease, a neurological disorder. The LITAF gene is mapped to chromosome number 16 and can be found at cytogenetic location 16p13 of chromosome. CMT1C-linked small integral membrane lysosome/late endosome mutants are loss-of-function that act dominant negative manner impair endosomal trafficking, leading prolonged extracellular signal-regulated...
Follicle-stimulating hormone-follicle-stimulating hormone receptor (FSH-FSHR) interaction is one of the most thoroughly studied signaling pathways primarily because being implicated in sexual reproduction mammals by way maintaining gonadal function and fertility. Despite material advances understanding role point mutations, their mechanistic basis FSH-FSHR still confined to mystically altered behavior sTYS335 (sulfated tyrosine) yet lacking a substantial theory. To understand structural...