A5101436222- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cerebrospinal fluid and hydrocephalus
- Traumatic Brain Injury and Neurovascular Disturbances
- Metabolomics and Mass Spectrometry Studies
- Body Contouring and Surgery
- Cardiovascular Syncope and Autonomic Disorders
- Traumatic Brain Injury Research
- Atomic and Subatomic Physics Research
- Cancer, Hypoxia, and Metabolism
- Adipose Tissue and Metabolism
- Heart Rate Variability and Autonomic Control
- Parathyroid Disorders and Treatments
- Cardiac and Coronary Surgery Techniques
- Analytical Chemistry and Chromatography
- Nutrition, Genetics, and Disease
- Fatty Acid Research and Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Advanced MRI Techniques and Applications
- Mass Spectrometry Techniques and Applications
- Advanced X-ray and CT Imaging
- Thermoregulation and physiological responses
- Blood properties and coagulation
- Fibroblast Growth Factor Research
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2024
Beijing Hospital
2014-2020
Abstract Objective Interstitial fluid in extracellular matrices may not be totally fixed but partially flow through long‐distance oriented fibrous connective tissues via physical mechanisms. We hypothesized there is a interstitial transport network beyond vascular circulations. Materials and methods first used 20 volunteers to determine hypodermic entrant points visualize extravascular pathway by MRI. then investigated the pathways initiating from point of thumb cadavers chest compressor....
Reducing low-density lipoprotein cholesterol (LDL-C) to target ≤1.81 mmol/L is a common therapeutic goal after acute coronary syndrome (ACS). This study aimed examine the factors associated with reaching or not this LDL-C 1 year of optimal statin therapy postpercutaneous intervention (PCI). was retrospective 633 consecutive prospectively enrolled patients ACS treated between January 2011 and December 2012 at Beijing Hospital (China). All were PCI statins for year. A multivariate analysis...
To determine the prognostic value of cumulative calcification score coronary artery (CAC), thoracic aortic (TAC) and valve (AVC) in acute ST segment elevation myocardial infarction (STEMI) patients.
The evaluation of pathobiome strains should be conducted at the strain level, involving identification functional genes, while considering impact ecological niche and drug interactions. safety, efficacy, quality management live biotherapeutic products (LBPs), especially strains, have certain peculiarities. Promising development methods include recombinant LBP active metabolites. As understanding gut microbiota's role in human health deepens, it is increasingly recognized that microbiota not...
Percutaneous coronary interventions (PCI) of bifurcation lesions is technically challenging and associated with lower success rates higher frequency adverse outcomes. In the present study, we aimed to evaluate immediate long-term treatment effect events a new modified jailed-balloon technique on side branch (SB) during PCI lesions. This was prospective study 60 patients (49 males, 11 females, mean age 66 ± 10 years) treated at Beijing Hospital between September 2014 October 2015. They...
Objective To evaluate the efficacy and safety of Paclitaxel drug coated balloon (DCB) (SeQuent Please©) in an elderly patients with de novo coronary disease. Methods We performed a retrospective study 158 consecutive (63 aged ≥65 yrs 95 <65 yrs) received DCB therapy Cath Lab Beijing Hospital. Clinical characteristic was recorded angiography analyzed quantitative angiography(QCA) software. Results In group, more have hypertension (65.1% vs. 56.8%), atrial fibrillation (7.9%...
The effects of the drug-coated balloon (DCB)-only strategy in treatment chronic total occlusion (CTO) coronary lesions remain controversial. Patients who underwent an in-stent restenosis (ISR) CTO percutaneous intervention (PCI) had a significantly poorer prognosis than those
This study aimed to evaluate the relationship between aromatic amino acids (AAAs), - phenylalanine (Phe), tyrosine (Tyr) and tryptophan (Trp) coronary artery disease (CAD) in a prospective involving 2970 participants undergoing angiography at Beijing Hospital. Serum levels of Phe, Tyr Trp were analysed. The cross-sectional data revealed that serum significantly inversely associated with CAD. During median follow-up period 44 months, 343 major adverse cardiovascular events (MACEs) 138...
Converging studies showed interstitial fluid (ISF) adjacent to blood vessels flows along adventitia of vasculature into heart and lungs. We aim reveal circulatory pathways regulatory mechanism such adventitial ISF flow in rat model. By MRI, real-time fluorescent imaging, micro-CT histological analysis, was found matrix surrounded by fascia systemic heart, then lungs via pulmonary arteries back veins, which neither perivascular tissues nor or lymphatic vessels. Under physiological conditions,...