A5027926145- Renin-Angiotensin System Studies
- Receptor Mechanisms and Signaling
- Neuropeptides and Animal Physiology
- Sodium Intake and Health
- Neurological Disease Mechanisms and Treatments
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
Consejo Nacional de Investigaciones Científicas y Técnicas
2014-2025
Universidad Nacional de Córdoba
2014-2025
Universidad Católica de Córdoba
2014-2019
Angiotensin II, is critical in regulating the sympathetic and neuroendocrine systems through angiotensin II type 1 receptors (AT1-R). intracerebral administration increases water sodium intake, as well renal excretion. Previously, our group has shown that AT1-R involved behavioral neurochemical sensitization induced by amphetamine. We aimed to assess physiological output, behavioral, responses administration, via AT1-R, twenty-one days after amphetamine administration. Male Wistar rats...
Central nucleus of the amygdala (CeA) is one most important regulatory centres for emotional processes. Among different neurotransmitter systems present in this nucleus, AT 1 receptors have been also found, but their role generation and modulation emotions not fully understood. The work evaluated effect intra-amygdalar injection losartan (AT receptor antagonist) angiotensin II (Ang II) anxiety state induced by fear-potentiated plus maze male Wistar rats. Fear elevated can be potentiated...
Abstract Amphetamine‐induced neuroadaptations involve vascular damage, neuroinflammation, a hypo‐functioning prefrontal cortex (PFC), and cognitive alterations. Brain angiotensin II, through type 1 receptor (AT ‐R), mediates oxidative/inflammatory responses, promoting endothelial dysfunction, neuronal oxidative damage glial reactivity. The present work aims to unmask the role of AT ‐R in development amphetamine‐induced changes over components within PFC hippocampus. Attention deficit was...