A5025421402- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Aortic Disease and Treatment Approaches
- Cardiovascular and Diving-Related Complications
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Acute Ischemic Stroke Management
- Anesthesia and Neurotoxicity Research
- Congenital Heart Disease Studies
- Blood Pressure and Hypertension Studies
- Diet and metabolism studies
- Intracranial Aneurysms: Treatment and Complications
- Intensive Care Unit Cognitive Disorders
- Venous Thromboembolism Diagnosis and Management
- Phonocardiography and Auscultation Techniques
- Pulmonary Hypertension Research and Treatments
- Renal and Vascular Pathologies
- Cardiac Imaging and Diagnostics
- Pericarditis and Cardiac Tamponade
- Cardiac Valve Diseases and Treatments
- Acute Kidney Injury Research
- Neonatal and fetal brain pathology
- Cardiac Ischemia and Reperfusion
Universidad de Ciencias Médicas de Cienfuegos
2025
St. Luke's Medical Center
2025
Ottawa Hospital
2002-2024
Hospital Universitari Germans Trias i Pujol
2024
University of Ottawa
2010-2023
Ottawa Hospital Research Institute
2013-2022
Deleted Institution
2021
University of Calgary
2016
University of California, San Francisco
1999-2016
Ottawa Heart Institute
2015
Human auditory steady state responses were recorded in 41 normal subjects and 22 patients with hearing loss. The effect of intensity on the at different tonal frequencies was assessed using sweep technique. amplitude increases phase delay decreases increasing intensity. Both are smaller for high frequency tone bursts. Notched noise response by a factor two but does not affect responses. Thresholds estimated waking techniques: sweeps analyzed linear regressions, fixed intensities Hotelling's...
High-intensity transient signals (HITS) are the transcranial Doppler representation of both air and solid cerebral emboli. We studied frequency HITS associated with different surgical maneuvers during cardiopulmonary bypass for coronary artery graft surgery their association postoperative cognitive dysfunction (POCD).We combined 356 patients undergoing from 2 clinical trials who had neuropsychological testing (before, 1 week 3 months after surgery) bypass. were grouped into periods that...
Background— Postoperative cognitive deficits (POCDs) are a source of morbidity and occur frequently even in low-risk patients undergoing cardiac surgery. Predictors neurocognitive can identify potentially modifiable risk factors as well high-risk whom alternate revascularization strategies may be considered. Methods Results— 448 coronary surgery (coronary artery bypass graft [CABG]) underwent standardized preoperative postoperative testing part 2 randomized trials evaluating the effects mild...
To determine the association between high-intensity transient signals (HITS) and perfusionist interventions, purging techniques, pump flows venous reservoir blood volume levels during cardiopulmonary bypass.Transcranial Doppler was used to detect HITS in middle cerebral artery period of aortic crossclamping patients undergoing coronary bypass grafting. Perfusionist-related interventions were recorded included sampling (including number times that oxygenator manifold purged), drug bolus...
When the right atrium (RA) cannula is connected to venous return line of cardiopulmonary bypass (CPB) circuit, air often introduced. Air in may increase cerebral embolization at initiation CPB despite arterial filter. We measured volume present after cannulation RA. Transcranial Doppler quantified emboli as high-intensity transient-signals (HITS) both middle-cerebral arteries (MCA) beginning CPB.After RA cannulation, column was and total calculated using known lumen diameter. onset defined...
Variations in core temperature and cerebral blood flow during open heart surgery may affect auditory brainstem responses (ABRs) middle latency (MLRs) both adults children. We documented the changes ABRs of two infants (ages 3 11 weeks, respectively) with variations hypothermic cardiopulmonary bypass total circulatory arrest compared them those a 19-year-old adult. Changes MLRs that occurred association reductions as monitored by transcranial Doppler are also reported 6-year-old child. With...
Background: The difficulty of distinguishing solid from air emboli using transcranial Doppler has limited its use in situations where both types can occur, such as mechanical heart valve patients. To make clinically useful, a method must be found to distinguish benign bubbles the more damaging particulates. Since inhalation 100% oxygen reduces amount patients, ultrasonic features remaining would characteristic Objective: We determined accuracy signal relative intensity measured with between...