Heidi R. Abd El-Hadi

ORCID: 0000-0002-6048-1673
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About
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Research Areas
  • Analytical Methods in Pharmaceuticals
  • Analytical Chemistry and Chromatography
  • Antibiotics Pharmacokinetics and Efficacy
  • Pesticide Residue Analysis and Safety
  • Ocular Infections and Treatments
  • Advanced Chemical Sensor Technologies
  • Electrochemical Analysis and Applications
  • Computational Drug Discovery Methods
  • Pharmacy and Medical Practices
  • Spectroscopy and Chemometric Analyses
  • Pregnancy and Medication Impact
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Nausea and vomiting management
  • Electrochemical sensors and biosensors

Egyptian Russian University
2020-2025

Abstract Nowadays, scientists are currently attempting to lessen the harmful effects of chemicals on environment. Stability testing identifies how a drug’s quality changes over time. The current work suggests first and sustainable differential pulse voltammetry technique for quantifying difluprednate (DIF) as an anti-inflammatory agent in presence its alkaline degradation product (DEG). optimum conditions developed method were investigated with glassy carbon electrode scan rate 100 mV s −1 ....

10.1038/s41598-024-61712-0 article EN cc-by Scientific Reports 2024-05-27

Triamterene (TRI) and xipamide (XIP) mixture is used as a binary medication of antihypertension which considered major cause premature death worldwide. The purpose this research the quantitative qualitative analysis by green univariate multivariate spectrophotometric methods. Univariate methods were zero order absorption spectra method (D0) Fourier self-deconvolution (FSD), TRI was directly determined D0 at 367.0 nm in range (2.00-10.00 µg/mL), where XIP show no interference. While FSD 261.0...

10.1186/s13065-023-00956-9 article EN cc-by BMC Chemistry 2023-05-13

Abstract Five sustainable and validated UV spectrophotometric methods were developed for analyzing chloramphenicol (CHL) dexamethasone sodium phosphate (DSP) in pure ophthalmic dosage forms. CHL was detected by zero order spectra method at 292.0 nm the range 2.00–32.00 µg/mL with limits of detection (LOD) quantification (LOQ) 0.96 2.88, respectively. DSP analyzed using following four techniques: Induce dual wavelength (IDW), fourier self-deconvolution (FSD), ratio difference (RD), derivative...

10.1038/s41598-025-96091-7 article EN cc-by Scientific Reports 2025-04-21

Abstract Green analytical procedures are gaining popularity in the pharmaceutical research area as a way to reduce environmental impact and improve analyst health safety. The current work presents green sensitive electrochemical carbon paste electrode that has been chemically modified with zirconium dioxide multi-walled nanotubes for estimation of pyridoxine HCl (PYR) doxylamine succinate (DOX) using square wave voltammetric technique. Under optimum conditions, linearity ranges were...

10.1007/s12678-022-00751-5 article EN cc-by Electrocatalysis 2022-07-08

The use of sustainable solvents has increased significantly in recent years due to advancements green analytical methods. number impurities the drug substance determines how safe finished product is. Therefore, during whole medication planning process, contaminants need be closely watched. Using chemometric models, concentrations hyoscine N-butyl bromide (HYO) and paracetamol (PAR) were determined presence three PAR [P-nitrophenol (PNP), P-aminophenol (PAP), P-chloroacetanilide (PCA), as...

10.1186/s13065-023-01089-9 article EN cc-by BMC Chemistry 2023-12-07

Abstract Background The combination of pyridoxine hydrochloride (PYR) and doxylamine succinate (DOX) as an antiemetic binary mixture is used to treat nausea vomiting during pregnancy. Objective Two validated, accurate, selective chemometric models were developed assay in the presence DOX oxidative degradation product (DOX DEG) that could be characterized using LC-MS. Methods Partial least squares (PLS) regression principal component (PCR) selected for determination our degradation. To...

10.1093/jaoacint/qsac090 article EN Journal of AOAC International 2022-07-29
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