Hengameh Sadeghi

ORCID: 0000-0002-6066-2108
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Autoimmune Bullous Skin Diseases
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Urticaria and Related Conditions
  • Bacterial Genetics and Biotechnology
  • Vector-borne infectious diseases
  • Animal Genetics and Reproduction
  • Air Quality and Health Impacts
  • CRISPR and Genetic Engineering
  • Molecular Biology Techniques and Applications
  • vaccines and immunoinformatics approaches
  • Monoclonal and Polyclonal Antibodies Research
  • Galectins and Cancer Biology
  • Diet, Metabolism, and Disease
  • Renal and Vascular Pathologies
  • Vascular Procedures and Complications
  • Viral Infectious Diseases and Gene Expression in Insects
  • Bacteriophages and microbial interactions
  • Genetics, Bioinformatics, and Biomedical Research
  • Celiac Disease Research and Management
  • Peripheral Artery Disease Management
  • Protein purification and stability
  • Malaria Research and Control
  • Diet and metabolism studies
  • Atherosclerosis and Cardiovascular Diseases
  • Psoriasis: Treatment and Pathogenesis

University of Lübeck
2012-2021

Cedars-Sinai Medical Center
1991-2021

Lung Institute
2018

Children's Medical Center
2017

Tehran University of Medical Sciences
2017

Cluster of Excellence "Inflammation at Interfaces"
2012-2014

Clinical Research Center Kiel
2012-2014

Islamic Azad University of Urmia
2013

Constructor University
2010

BACKGROUND We have previously shown that continuous-wave ultrasound can rapidly dissolve human thrombi in vitro, with 99% of all residual particles measuring less than 10 microns diameter. To assess the effects pulsed-wave energy on whole blood clots, 1) vitro studies were preformed to precisely rates clot disruption and quantify particulate size, 2) vivo performed efficacy safety catheter-delivered for intra-arterial thrombus dissolution. METHODS AND RESULTS In we studied 50 samples clots...

10.1161/01.cir.84.4.1680 article EN Circulation 1991-10-01

Abstract Although reports documented aberrant cytokine expression in autoimmune bullous dermatoses (AIBDs), cytokine-targeting therapies have not been established these disorders. We showed previously that IL-6 treatment protected against tissue destruction experimental epidermolysis bullosa acquisita (EBA), an AIBD caused by autoantibodies to type VII collagen (COL7). The anti-inflammatory effects of were mediated induction IL-1ra, and prophylactic IL-1ra administration prevented...

10.4049/jimmunol.1402688 article EN The Journal of Immunology 2015-03-21

Abstract Genetic studies have added to the understanding of complex diseases. Here, we used a combined genetic approach for risk‐loci identification in prototypic, organ‐specific, autoimmune disease, namely experimental epidermolysis bullosa acquisita ( EBA ), which autoantibodies type VII collagen COL7 ) and neutrophil activation cause mucocutaneous blisters. Anti‐ IgG induced moderate blistering most inbred mouse strains, while some showed severe disease or were completely protected. Using...

10.1002/path.4556 article EN The Journal of Pathology 2015-05-07

Objectives: Celiac disease is a chronic autoimmune in which gene-environment interactions cause the immune system to unfavorably react naturally gluten-containing foods. PTPN22 plays crucial role regulating function of various cells system, particularly T cells. Polymorphisms gene have been associated with many diseases. The present genetic association study was conducted investigate possible associations between PTPNTT single nucleotide polymorphisms (SNPs) and celiac an Iranian population....

10.1080/15513815.2017.1290725 article EN Fetal and Pediatric Pathology 2017-05-04
Coming Soon ...