A5017235084- Cardiac Health and Mental Health
- Acute Myocardial Infarction Research
- Health Systems, Economic Evaluations, Quality of Life
- Sex and Gender in Healthcare
- Heart Failure Treatment and Management
- Atrial Fibrillation Management and Outcomes
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Lipoproteins and Cardiovascular Health
- Blood Pressure and Hypertension Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Issues in Pregnancy
- Cardiovascular Function and Risk Factors
- Congenital Heart Disease Studies
- Pregnancy and preeclampsia studies
- Pharmaceutical Economics and Policy
- Healthcare Policy and Management
- Health disparities and outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Health and Risk Factors
- Pharmaceutical Practices and Patient Outcomes
- Cardiovascular Disease and Adiposity
- Coronary Interventions and Diagnostics
- Medication Adherence and Compliance
McGill University
2016-2025
McGill University Health Centre
2016-2025
Universidad de Murcia
2020-2025
Centre Hospitalier de l’Université de Montréal
2006-2025
Alberta Hospital Edmonton
2016-2023
Alberta Health
2020-2022
Alberta Health Services
2020-2022
University of Ottawa
2009-2021
German Centre for Cardiovascular Research
2019-2021
Paraza Pharma (Canada)
2021
Background— Empirical data on the changing epidemiology of congenital heart disease (CHD) are scant. We determined prevalence, age distribution, and proportion adults children with severe other forms CHD in general population from 1985 to 2000. Methods Results— Where healthcare access is universal, we used administrative databases that systematically recorded all diagnoses claims. Diagnostic codes conformed International Classification Disease , ninth revision. Severe was defined as...
Background— Atrial arrhythmias increase disease burden in the general adult population. Adults with congenital heart lesions constitute a rapidly growing group of patients cardiovascular disease. We hypothesized that atrial age and impair health outcomes this Methods Results— conducted population-based analysis prevalence, lifetime risk, mortality, morbidity associated adults from l983 to 2005. In 38 428 2005, 5812 had arrhythmias. Overall, 20-year risk developing arrhythmia was 7%...
The authors compared five methods of studying survival bias associated with time-to-treatment initiation in a drug effectiveness study using medical administrative databases (1996-2002) from Quebec, Canada. first two illustrated how could be introduced. Three additional were considered to control for this bias. Methods the context evaluating statins secondary prevention elderly patients post-acute myocardial infarction who initiated within 90 days after discharge and those did not. Method 1...
Background— Current observational studies on warfarin use and the risk for stroke bleeding in patients with atrial fibrillation (AF) undergoing dialysis found conflicting results. Methods Results— We conducted a population-based retrospective cohort study of aged ≥65 years admitted to hospital primary or secondary diagnosis AF, Quebec Ontario, Canada from 1998 2007. The AF was grouped into (hemodialysis peritoneal dialysis) nondialysis no-warfarin users according first prescription filled...
Background— Clinical guidelines recommend specialized care for adult congenital heart disease (ACHD) patients. In reality, few patients receive such dedicated care. We sought to examine the impact of on ACHD patient mortality. Methods and Results— examined referral rates centers mortality between 1990 2005 in population-based Quebec Congenital Heart Disease database (n=71 467). This period covers several years before after publication endorsing A time-series design, based Joinpoint Poisson...
Stroke is a serious complication associated with atrial fibrillation (AF). Women AF are at higher risk of stroke compared men. Reasons for this in women remain unclear, although some studies suggest that undertreatment warfarin may be cause.To compare utilization patterns and the subsequent between older men population level.Population-based cohort study patients 65 years or admitted to hospital recently diagnosed province Quebec, Canada, 1998-2007, using administrative data linkage...
To create a gender index by using principal component analyses (PCA) and logistic regression, to determine the association between gender, sex, cardiovascular risk factors among patients with premature acute coronary syndrome (ACS).GENESIS-PRAXY is cohort study including ACS aged 55 years or below, recruited 2009 2013 from 26 centres across Canada, United States, Switzerland. A sample of 1075 was used for this study. Psychosocial variables assumed differ sexes (i.e., related) were included...
In this paper, we argue for Gender as a Sociocultural Variable (GASV) complement to Sex Biological (SABV). (biology) and gender (sociocultural behaviors attitudes) interact influence health disease processes across the lifespan-which is currently playing out in COVID-19 pandemic. This study develops assessment tool-the Stanford Gender-Related Variables Health Research-for use clinical population research, including large-scale surveys involving diverse Western populations. While analyzing...
Scalable deprescribing interventions may reduce polypharmacy and the use of potentially inappropriate medications (PIMs); however, few studies have been large enough to evaluate impact that on adverse drug events (ADEs).To effect an electronic decision support tool ADEs after hospital discharge among older adults with polypharmacy.This was a cluster randomized clinical trial (≥65 years) hospitalized patients expected survival more than 3 months who were admitted 1 11 acute care hospitals in...
Much attention has been directed to the use of medical resources and patients' outcomes in Canada as compared with United States. We U.S. Canadian patients respect their quality life during year after acute myocardial infarction.
Differences in the management of acute myocardial infarction have been reported among countries, but few studies investigated this issue regions United States.
Protease inhibitors are potent antiviral agents against human immunodeficiency virus type 1. As with reverse transcriptase inhibitors, however, resistance to protease can develop and is attributed the appearance of mutations in gene. With substrate analog BILA 1906 BS 2185 BS, 350- 1,500-fold-resistant variants have been selected vitro were found not only contain gene but also Gag precursor p1/p6 and/or NC (p7)/p1 cleavage sites. Mutations sites give rise better peptide substrates for...
Background— Many patients with congenital heart disease (CHD) require lifelong care. However, the duration of cardiology follow-up in children and adults CHD is unknown. We sought to determine proportion young receiving outpatient care identify predictors lack follow-up. Methods Results— The study population consisted individuals born 1983 alive at age 22 years who were diagnosed Quebec, Canada, before 6 (n=643). Patients visits identified use provincial physician’s claims database. Three...