A5032291858- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Screening and Detection
- Pancreatitis Pathology and Treatment
- Liver Disease Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Inflammatory Bowel Disease
- Gastric Cancer Management and Outcomes
- Microscopic Colitis
- Esophageal and GI Pathology
- Cancer survivorship and care
- Diet and metabolism studies
- Cancer Genomics and Diagnostics
- Clinical Nutrition and Gastroenterology
- Pediatric Hepatobiliary Diseases and Treatments
- Palliative Care and End-of-Life Issues
- Childhood Cancer Survivors' Quality of Life
- Hepatitis C virus research
- Neuroendocrine Tumor Research Advances
- Gastroesophageal reflux and treatments
- Gastrointestinal motility and disorders
- HIV Research and Treatment
- Esophageal Cancer Research and Treatment
- Adolescent and Pediatric Healthcare
- Bariatric Surgery and Outcomes
- Liver Diseases and Immunity
Shaheed Zulfiqar Ali Bhutto Institute of Science and Technology
2025
Advocate Lutheran General Hospital
2024
MetroHealth Medical Center
2016-2023
Allegheny Health Network
2018-2023
Case Western Reserve University
2007-2023
West Virginia University
2022
Western University of Health Sciences
2019-2020
Stony Brook University Hospital
2020
Allegheny-Singer Research Institute
2019
University Gastroenterology
2018
We aimed to establish the epidemiological characteristics and documentation of diagnostic workup for gastroparesis (GP).No study has used a national database evaluate prevalence, demographics, associated comorbid conditions GP, document rates proper diagnosis.This was cross-sectional population-based using Explorys Platform determine prevalence GP in large diverse population highly representative US examine approach GP. Data collected were individual from electronic medical records (EMRs)...
Colorectal cancer (CRC) is the second leading cause of all related deaths in United States and Europe. Although incidence has been decreasing for individuals' ≥ 50, it on rise individuals < 50.To identify potential risk factors early-onset CRC.A population-based cohort analysis using a national database, Explorys, screened patients with an active electronic medical record from January 2012 to December 2016 diagnosis CRC. Subgroups were stratified based age (25 - 49 years vs 50 years)....
The aim of this study was to evaluate depression in pancreatic cancer (PC) patients before and after a diagnosis using US-based healthcare database. We also sought the impact treatment PC on all-cause mortality.Pancreatic with comorbid Explorys (1999-2019) were compared controls odds ratios 95% confidence intervals. Rates diagnosed within 6 months, 1 year, 3 years recorded. Patients who developed further categorized into those treated for mental health professionals (MHPs), pharmacologic...
Gastroesophageal reflux disease (GERD) manifests in distinct phenotypes, including erosive (ERD) and nonerosive (NERD), which exhibit differences pathophysiology clinical outcomes. This study aims to explore microbial across these phenotypes. RNA sequencing data of 69 esophageal samples from esophagitis (RE) NERD patients were retrieved NCBI SRA identify key taxa. Alpha beta diversity analyses conducted, DESeq2 Lefse used bacterial biomarkers differentiate ER NERD. Five dominant phyla...
Objectives Acute and/or chronic pancreatitis has been implicated as an important risk factor for pancreatic cancer; however, the incidence and temporal relationship of before cancer diagnosis are unclear. We aim to understand role temporally with development cancer. Methods A population-based study was used investigate a between diagnoses. Intervals 3, 6, 12, 24, 36 months were developed. Demographical data including age, sex, race also recorded analyzed. Results total 50,080 patients found...
ABSTRACT This study has adapted the oligonucleotide ligation assay (OLA) to probe for low-level nevirapine (NVP) resistance mutations K103N and Y181C in human immunodeficiency virus type 1 (HIV-1) population of infected mother-infant pairs from Uganda. When NVP is used prevent perinatal transmission, NVP-resistant HIV-1 clones may be rapidly selected due a low barrier mutation relatively high level fitness (compared that other drug-resistant clones). Monitoring even frequency help predict...
Summary Background An association between bariatric surgery and development of de‐novo inflammatory bowel disease (IBD) has been observed. Aim To evaluate further the among surgery, weight loss medications, obesity new‐onset IBD. Methods Using Explorys, a population‐based Health Insurance Portability Accountability Act compliant database, we estimated prevalence IBD patients treated with (Roux‐en‐Y gastrojejunostomy, laparoscopic sleeve gastrectomy or gastric banding) (n = 60 870)...
Abstract Background Endoscopic ultrasound (EUS) guided core needle biopsies (CNB) are increasingly being performed to diagnose solid pancreatic lesions. However, studies have been conflicting in terms of CNB improving diagnostic accuracy and procedural efficiency vs fine‐needle aspiration (FNA), which this study aims elucidate. Methods Data were prospectively collected on consecutive patients with or peripancreatic lesions at a single tertiary care center from November 2015 2016 that...
Background: Liver transplant is the only cure for cirrhosis. We studied impact of palliative care on patient by conducting a population-based cohort study. Methods: queried Explorys database (IBM, New York) diagnosis 'cirrhosis' followed 'palliative consultation' and collected demographic clinical data. Results: identified 316,970 patients with Palliative was consulted 10.9% (n = 34,600) patients. Patients aged >65 [OR 1.33 (1.30-1.36), P < .0001], men 1.13 (1.11-1.16), hepatocellular...
This study explores the levels of NVP and AZT resistance mutations in untreated, NVP- or AZT-treated mother–infant pairs Uganda. PCR-amplified reverse transcriptase (RT) gene fragments derived from PBMC samples 85 mothers (10 treated, 35 40 untreated) their 52 infected infants (5 AZT, 9 NVP, 38 were classified as subtype A (59%), D (29%), C (3%), recombinant forms (9%) by population sequencing. Only 16% NVP-treated harbored either K103N Y181C at 6 weeks postdelivery. The majority these (n =...
Objectives Surgery is the curative treatment for pancreatic ductal adenocarcinoma (PDA). Guidelines recommend utilizing a multidisciplinary cancer conference (MDPC) in treatment; however, data are limited. The objective of this study was to assess accuracy an MDPC. Methods Patients with PDA presented at MDPC were prospectively collected from April 2013 August 2016. included if predicted them have resectable and underwent upfront surgery. Secondary aims compare differences tumor...
Abstract Background Surveillance colonoscopy 1 year after resection of colorectal cancer is recommended by all major societies, including National Comprehensive Cancer Network and United States Multi Society Task Force. Study objectives Our study assesses adherence to post surveillance guidelines at a large tertiary care center aims identify reasons for non-adherence. Methods A retrospective was conducted patients who underwent curative between January 2016 June 2017. Adherence...
Radiation exposure during endoscopic retrograde cholangiopancreatography is known, however, data in relation to radiation usage unclear. We evaluate using fluoroscopy dose (FD) and time (FT). A prospective analysis of 197 patients undergoing was completed. Univariate multivariate analyses were performed determine characteristics associated with higher FD FT. The mean FT 307 seconds; the 16.5 centigray. On univariate analysis, indication common bile duct stricture pancreatic stricture,...
Introduction The research was conducted to explore the mental health issues, including anxiety, depression, low mood, emotional irrationality, and stressors related pregnancy in tertiary care hospital, Karachi, after getting diagnosed with a life-threatening virus of hepatitis C determine factors associated depression among HCV-infected pregnant women. There appears be dearth literature on this particular topic, women might not dealt effectively till gap is addressed. findings are aid...
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