A5079824501- Berberine and alkaloids research
- Ginger and Zingiberaceae research
- Pharmacological Effects of Natural Compounds
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Drug Transport and Resistance Mechanisms
- Magnolia and Illicium research
Guangdong Pharmaceutical University
2017-2018
State Administration of Traditional Chinese Medicine of the People's Republic of China
2018
Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy that often resistant to therapy. Nowadays, chemotherapy still one of the main methods for treatment ESCC. However, multidrug resistance (MDR)-mediated leading causes death. Exploring agents able reverse MDR, which thereby increase sensitivity with clinical first-line drugs, could significantly improve cancer treatment. Cepharanthine hydrochloride (CEH) has ability MDR in ESCC and mechanism involved have not been reported....