Sleep, anesthesia and coma share a number of neural features but the recovery profiles are radically different. To understand mechanisms reversibility unconsciousness at network level, we studied conditions for gradual abrupt state transitions in conscious anesthetized states. We hypothesized that explosive synchronization (ES) human brain networks would be present just over threshold unconsciousness. test this hypothesis, functional were constructed from multi-channel electroencephalogram...

Abstract Fibromyalgia (FM) is a chronic widespread pain condition characterized by augmented multi-modal sensory sensitivity. Although the mechanisms underlying this sensitivity are thought to involve an imbalance in excitatory and inhibitory activity throughout brain, neural network properties associated with hypersensitivity stimuli largely unknown. In science, explosive synchronization (ES) was introduced as mechanism of diverse biological physical systems that display global propagations...

Abstract Introduction Recent evidence suggests that the conscious brain is characterized by a diverse repertoire of functional connectivity patterns while anesthetized shows stereotyped activity. However, classical time‐averaged methods dismiss dynamic and temporal characteristics configurations. Here we demonstrate new approach which characterizes time‐varying at subsecond time scale. Methods We introduce phase‐lag entropy (PLE), measure diversity in phase relationships between two signals....

How the brain reconstitutes consciousness and cognition after a major perturbation like general anesthesia is an important question with significant neuroscientific clinical implications. Recent empirical studies in animals humans suggest that recovery of not random but ordered. Emergence patterns have been classified as progressive abrupt transitions from to consciousness, associated differences duration electroencephalogram (EEG) properties. We hypothesized emergence unconscious state are...

Pulse wave velocity (PWV) is thought to have different relationships with metabolic syndrome (MS) components, inflammatory markers, and oxidative stress, according age. However, age-specific determinants of PWV not yet been studied. We investigated age-dependent among MS stress.A total 4,318 subjects were divided into 4 groups: 19-34 y (n=687), 35-44 (n=1,413), 45-54 (n=1,384), 55-79 (n=834). brachial-ankle (baPWV), high-sensitivity C-reactive protein (hs-CRP), stress markers measured.There...

Abstract Identifying how spatially distributed information becomes integrated in the brain is essential to understanding higher cognitive functions. Previous computational and empirical studies suggest a significant influence of network structure on function. However, there have been few analytical approaches explain role shaping regional activities directionality patterns. In this study, methods are applied coupled oscillator model implemented inhomogeneous networks. We first derive...

Abstract Sickle cell disease (SCD) is a genetic disorder causing painful and unpredictable Vaso-occlusive crises (VOCs) through blood vessel blockages. In this study, we propose explosive synchronization (ES) as novel approach to comprehend the hypersensitivity occurrence of VOCs in SCD brain network. We hypothesized that accumulated disruptions network induced by might lead strengthened ES hypersensitivity. explored ES's relationship with patient reported outcome measures (PROMs) well...

Continuous switching between internal and external modes in the brain appears important for generating models of self world. However, how transitions these two remains unknown. We propose that a large synchronization fluctuation networks, emerging only near criticality (i.e., balanced state order disorder), spontaneously creates temporal windows with distinct preferences integrating network's information or processing stimuli. Using computational model, electroencephalography (EEG) analysis,...

Brains in unconsciousness are characterized by significantly limited responsiveness to stimuli. Even during conscious wakefulness, is highly dependent on ongoing brain activity, specifically, of alpha oscillations (∼10 Hz). We hypothesized that the variety responses external stimuli result from interaction between state-specific and transient To justify this hypothesis, we simulated various human network, modulating criticality (a balanced state order disorder), investigated specific...

Fibromyalgia (FM) is a chronic pain condition that characterized by hypersensitivity to multimodal sensory stimuli, widespread pain, and fatigue. We have previously proposed explosive synchronization (ES), phenomenon wherein small perturbation network can lead an abrupt state transition, as potential mechanism of the hypersensitive FM brain. Therefore, we hypothesized converting brain from ES general (GS) may reduce To find effective modulation convert into GS, constructed large-scale model...

Background Neurophysiologic complexity in the cortex has been shown to reflect changes level of consciousness adults but remains incompletely understood developing brain. This study aimed address cortical related age and anesthetic state transitions. tested hypotheses that would (1) increase with developmental (2) decrease during general anesthesia. Methods was a single-center, prospective, cross-sectional healthy (American Society Anesthesiologists physical status I or II) children (n = 50)...

This study aimed to compare the nutrient uptake rate, growth and yield of strawberry grown under aquaponic hydroponic systems in a plant factory. For aquaculture, 12 fish (Cyprinus carpio cv. Koi) were raised an aquaponics tank (W 0.7 m × L 1.5 H 0.45 m, 472.5 L) filled with 367.5L water at density 5.44 kg·m-3. The 30 seedlings planted ports perlite substrate then placed on bed 0.22 m) top system, net-pots holes acrylic plates (140 cm 60 cm, Ø80 mm) deep flow technique (DFT)- hydroponics. pH...

When complex systems move away from criticality-a balance between order and chaos-they are no longer optimized. Furthermore, when criticality is lost too quickly, or recovery delayed, system damage can result. However, the mechanism for these abnormally fast slow critical transitions remains unknown. Here, we show that proximity of a network to explosive synchronization (ES), first-order phase transition, determines trajectories loss after perturbations. Our computational models revealed...

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In this paper, the effect of visual angle and response time display on flicker perception was studied. The influence size observed using 30 Hz simulation image two type displays with fast slow time. Participants percived that became stronger as stimulus increased, but it there no by display. However, indices such JEITA, visibility are used international standards, do not reflect these perceptual characteristics. Flicker need to be supplemented.

The present study was designed to investigate how users neurologically respond self-relevant virtual avatars when they identify the as themselves. In particular, using an electroencephalogram (EEG) measures, this aimed explore physiologically wearing their own faces. 25 undergraduate students participated in ERP-based experiment at a large university Seoul, Korea. 2×4 within-subjects factorial design, each subject exposed eight combinations of two types face presentations (photo faces vs....