A5045111275- Gut microbiota and health
- Mycobacterium research and diagnosis
- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Tuberculosis Research and Epidemiology
- interferon and immune responses
- Resilience and Mental Health
- Corporate Social Responsibility Reporting
- Cytokine Signaling Pathways and Interactions
- Cancer-related molecular mechanisms research
- Job Satisfaction and Organizational Behavior
- Immune Cell Function and Interaction
- Listeria monocytogenes in Food Safety
- Immune Response and Inflammation
- Auditing, Earnings Management, Governance
- Education, Safety, and Science Studies
- Healthcare Education and Workforce Issues
- Helicobacter pylori-related gastroenterology studies
- Child Nutrition and Water Access
- Risk and Safety Analysis
- Inflammatory Bowel Disease
- Corporate Finance and Governance
- Clostridium difficile and Clostridium perfringens research
Guangdong Province Women and Children Hospital
2024-2025
Sun Yat-sen University
2021-2024
China General Nuclear Power Corporation (China)
2024
Guangxi University of Finance and Economics
2018
The gut-lung axis has been implicated as a potential therapeutic target in lung disorders. While increasing evidence suggests that gut microbiota plays critical role regulating host immunity and contributing to tuberculosis (TB) development progression, the underlying mechanisms whereby may impact TB outcomes are not fully understood. Here, we found broad-spectrum antibiotics treatment increased susceptibility Mycobacterium (M. tuberculosis) infection modulated pulmonary inflammatory...
Magnitude and diversity of gut microbiota metabolic systems are critical in shaping human health diseases, but it remains largely unclear how complex metabolites may selectively regulate determine diseases. Here, we show that failures or compromised effects anti-TNF-α therapy inflammatory bowel diseases (IBD) patients were correlated with intestinal dysbacteriosis more pro-inflammatory bacteria, extensive unresolved inflammation, failed mucosal repairment, aberrant lipid metabolism,...
Diarrheal diseases caused by gastrointestinal pathogens contribute to the high morbidity and mortality in children worldwide. Salmonella infection is one of leading causes diarrhea, especially under 5 years age. This study aimed assess prevalence its co-infection patterns relation clinical symptoms. A total 430 stool samples with diarrheal were collected from Guangdong Women Children's Hospital during January 2022 December 2023 used for detection. BioFire FilmArray Gastrointestinal (GI)...
Unlike previous studies in which a single index was used to measure audit quality, this study establishes new comprehensive quality via Discretionary Accrual, as estimated by Jones' basic model (1991) and Audit Opinions. The former is the of financial statements, latter auditors' independence mainstream international literature. We examine whether how an auditor's gender affects his or her audits under framework empathy theory role socialization theory. Using large sample 9861...
Tuberculosis (TB), which is a frequent and important infectious disease caused by Mycobacterium tuberculosis, has resulted in an extremely high burden of morbidity mortality. The importance intestinal dysbacteriosis regulating host immunity been implicated TB, accumulating evidence suggests that microRNAs (miRNAs) might act as key mediator maintaining homeostasis through signaling networks. However, the involvement miRNA gut microbiota, TB immune system remains unknown. Here we showed...
Tuberculosis (TB) induced by Mycobacterium tuberculosis (M. tuberculosis) infection remains a global most deadly infectious disease. While development of more effective TB vaccines and therapeutics relies on identifications true biomarkers designating an immune protection against M. infection, exact protective components remain largely unidentified. We previously found that severe remarkable up-regulation interferon regulatory factor 7 (IRF7) IRF7-related gene signatures, implicating some...
Acute gastroenteritis caused by
Objective Although previous research has indicated that human errors represent the primary cause of incidents in nuclear power safety, few studies have investigated potential impact psychological factors on performance operators. This study makes a pioneering contribution to field by integrating effect personal states and personality traits work evaluation.
We explored the effect of cognitive states and personalities on work performance. recruited 101 commissioning workers in nuclear power plants (NPPs) tracked their before daily self-evaluated performance after over ten consecutive workdays. Corsi blocks-tapping task, go/no-go visual search multitasking paradigm were used to measure pre-work working memory, perception, attention, executive control respectively. Conscientiousness, mindfulness, body awareness, anxiety measured as personality...
Abstract Both host genetics and gut microbiome have important effects on human health, yet how regulates bacteria further determines disease susceptibility remains unclear. Here, we find that pattern of active tuberculosis (TB) patients is characterized by a reduction core species found across healthy controls, particularly Akkermansia muciniphila ( A. ). Oral treatments or palmitoleic acid, an -derived metabolite, strongly inhibit TB infection through epigenetically inhibiting TNF-α. We use...