A5101456750- Osteoarthritis Treatment and Mechanisms
- Knee injuries and reconstruction techniques
- Growth Hormone and Insulin-like Growth Factors
- Musculoskeletal synovial abnormalities and treatments
- Cell Adhesion Molecules Research
- T-cell and Retrovirus Studies
- Rheumatoid Arthritis Research and Therapies
- Bone health and treatments
- Protease and Inhibitor Mechanisms
- Neurogenetic and Muscular Disorders Research
- Genetics and Physical Performance
- Total Knee Arthroplasty Outcomes
King George's Medical University
2017-2019
Abstract Background Osteoarthritis (OA) is a common cause of musculoskeletal disability among elders and characterized by late-onset degeneration articular cartilage. OA affects various joints, commonly hand, knee, hip, with clinical features that are unique to each joint. This study was initiated identify evaluate the role ASPN COMP genes in development knee OA. Methods A case–control carried out involving 500 cases (diagnosed American College Rheumatology) an equal number healthy controls....
The present study investigated to identify the association of polymorphism in GDF-5 gene with osteoarthritis North Indian population. In a case-control study, 300 cases knee and an equal number age gender matched healthy controls were included. Cases diagnosed using ACR Guidelines Knee Osteoarthritis (KOA). Clinical symptoms assessed specific WOMAC index VAS for pain. severity disease was determined by radiological KL grades (Kellgren Lawren). variant genotype found be at significantly...
Introduction . Genetic factors including the level of expression fingerprint genes involved in development bones and cartilage such as GDF-5 or ESR- α CALM-1 are known to be strong determinants osteoarthritis (OA) Caucasian Oriental populations. Because high prevalence OA Indian population availability limited genetic data, we determined whether similar Indians well. Methods A case control study was carried out involving 500 patients knee equal number healthy controls. Genotyping analyses...