A5053478812- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Chromatography in Natural Products
- Sesquiterpenes and Asteraceae Studies
- Gut microbiota and health
- Phytochemicals and Antioxidant Activities
- Nanomaterials for catalytic reactions
- Nanoporous metals and alloys
- Liver Disease Diagnosis and Treatment
- Supercapacitor Materials and Fabrication
- Phytochemical Studies and Bioactivities
- Traditional Chinese Medicine Analysis
- Food Quality and Safety Studies
- Polysaccharides and Plant Cell Walls
- Phytochemistry and biological activity of medicinal plants
- Plant biochemistry and biosynthesis
- Peroxisome Proliferator-Activated Receptors
- Plant Toxicity and Pharmacological Properties
- Plant-based Medicinal Research
- Metabolomics and Mass Spectrometry Studies
- Heavy metals in environment
- Natural Antidiabetic Agents Studies
- Saffron Plant Research Studies
- Bioactive natural compounds
- Phytochemical compounds biological activities
Soochow University
2014-2025
Lanzhou University
2023-2024
Changshu Institute of Technology
2023
Hebei University of Technology
2014-2021
Nanjing University of Chinese Medicine
2019-2021
Jiangsu Provincial Academy of Traditional Chinese Medicine
2021
Tianjin University of Technology
2019
Soochow University
2009-2014
Chinese Academy of Medical Sciences & Peking Union Medical College
2002-2007
Institute of Medicinal Plant Development
2002
Introduction Long-term heavy metal contamination of soil affects the structure and function microbial communities. The aim our study was to investigate effect on microorganisms impact different pollution levels interactions. Methods We collected samples determined properties. Microbial diversity analyzed in two groups using high-throughput sequencing technology. Additionally, we constructed networks analyze Results load index (PLI) < 1 indicates that area is not polluted. PLI 2...
Chalocomoracin (CMR), one of the major secondary metabolites found in fungus-infected mulberry leaves, is a potent anticancer agent. However, its mechanism remains elusive. Here, we demonstrated anti-tumor activity and molecular CMR both vitro vivo. We showed for first time that treatment markedly promoted paraptosis along with extensive cytoplasmic vacuolation derived from endoplasmic reticulum, rather than apoptosis, PC-3 MDA-MB-231cell lines. Additional studies revealed ectopic expression...
Peoniflorin (PF) and albiflorin (AF) are two principal components of Paeonia species, which exhibit various biological activities such as improvement blood circulation immunoregulating function. To further utilization waste parts peony plants, an efficient method for preparative purification these ingredients from white rhizome was developed based on macroporous resin (MAR) medium-pressure liquid chromatography (MPLC). The separation characteristics nine typical MARs were investigated by...
Microglia activation-mediated neuroinflammation plays an important role in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's multiple sclerosis, and human immunodeficiency virus (HIV)-associated dementia. Inhibition microglia activation may alleviate neurodegeneration under neuroinflammatory conditions. In present study, we compared three flavone C-glycosides extracted from Trollius chinensis BUNGE using a cell-based assay to evaluate their...
Abstract The objective of the study was to evaluate effect hypoproteinemia on prognosis sepsis patients and effectiveness exogenous albumin supplementation. A retrospective cohort conducted in adult ICUs. subjects were 1055 MIMIC III database from June 2001 October 2012. There no interventions. total enrolled allocated into two groups based lowest in-hospital level: 924 group (the ≤ 3.1 g/dL) 131 normal > g/dL). 378 [331 (35.8%) group, 47 (35.9%) group] died at 28 days, statistically...
Abstract Eighteen different triterpene saponins isolated from Polygala tenuifolia were investigated by electrospray ionization ion trap multiple‐stage mass spectrometry (ESI‐ITMS n ) in positive and negative modes. MS 1 ‐MS 3 /MS 4 spectra of the both modes analyzed, they all gave fragments line shared common fragmentation patterns. Key their proposed pathways constructed with examples illustrated for formation characteristic saponins. Two special patterns proposed: (1) cleavage CH 2 O Δ 12...
To identify the chemical structure of Coreopsis tinctoria extracts and their effect mechanism on reducing blood lipid in hyperlipemia mice. The flavonoids were extracted from tinctoria. was identified by HPLC. 59 mice divided randomly into 5 groups. (group 1: normal diet control; group 2: model; 3: treated with tinctoria, low dose 100 mg/kg; 4: high 200 Fenofibrate. After 2 week hyperlipid diet, treatment Fenofibrate given for another 6 weeks continuous diet. TC, TG, HDL, histology, adipose...
Gardenia fruits contain valuable natural food colorants including crocins (gardenia yellow) and geniposide. In this study, a process for the enrichment of geniposide simultaneously from gardenia was developed using macroporous resin RP chromatography. The performance eight different types resins evaluated. Static absorption/desorption experiments revealed that LX60 possessed optimal separating capacity. Further dynamic on columns were conducted to obtain parameters. After one run treatment...
Fatty liver is associated with intestinal microbiota dysbiosis and low-grade chronic inflammation. Herein we report the interaction of flavonoid extract from Smilax glabra Roxb. (FSGR) gut microbiota. Then, FSGR's function modulating in a rat model high-fat diet (HFD) induced fatty has been explored. These investigations indicated that main compound FSGR, such as astilbin its isomers, could be metabolized to aglycone, while further splitting resulted some phenolic acid compounds through...
Rheumatoid arthritis (RA) is an essential cause of labor loss and disability for people worldwide. Acanthopanax senticosus polysaccharide (ASPS) one the most important active components from A. senticosus, which exhibits various pharmacological activities such as antioxidation immunomodulation. However, no studies have reported application ASPS in treating RA. This study aims to investigate therapeutic effect on RA reveal its underlying mechanism. The potential against initially verified...
Mountain Zizania latifolia is produced at scale in China, and the edible swollen culm exported to many countries, but little attention has been paid its functional components. In this work, microwave-assisted enzymatic extraction (MAEE) used for first time extract polysaccharides from mountain Z. (PMZL). MAEE conditions optimized by Box-Behnken design-response surface methodology were as follows: 2.4% cellulase, microwaving 6.0 min 607 W, with a liquid-to-solid ratio of 63:1 ml g-1 . Under...
Microbial colonization represents one of the main threats to conservation subterranean cultural heritage sites. Recently, microbial on murals in tombs has gradually attracted attention.In this study, a total 33 samples, including 27 aerosol samples and 6 mural painting were collected from different sites Xu Xianxiu's Tomb analyzed using culture-dependent methods. We compared diversities culturable bacteria fungi isolated air explored potential impacts microorganisms biodeterioration...