- Diabetes and associated disorders
- Genomics and Rare Diseases
- Protein Tyrosine Phosphatases
- Neuroblastoma Research and Treatments
- Immunodeficiency and Autoimmune Disorders
- Growth Hormone and Insulin-like Growth Factors
- Diet, Metabolism, and Disease
- Diabetes Management and Research
- Stress Responses and Cortisol
- Hypothalamic control of reproductive hormones
- RNA modifications and cancer
- Ovarian function and disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pituitary Gland Disorders and Treatments
Dokuz Eylül University
2022-2025
Owl Research Institute
2022
Early puberty is development of secondary sex characteristics earlier than the expected normal age range. We subjectively observed an increased frequency early during Coronavirus disease-2019 (COVID-19) lockdown and aimed to show clinical, demographic cases change in its incidence.Female patients with central precocious (CPP, n=28) rapidly progressive (RPEP, n=61), presenting our clinic before (January 2019-March 2020) COVID-19 pandemic (April 2020-June 2021) were included.Among 28 CPP...
Cancer can occur in patients with Noonan syndrome (NS). Review of English literature revealed that myeloproliferative diseases are the most prevalent, followed by intracranial tumours. There is no genotype phenotype relationship between germline pathogenic variants so it not possible to precisely predict cancer risk NS, however some PTPN11 exclusively detected juvenile myelomonocytic leukemia and observed other types cancer. Among on growth hormone, development was reported seven genetically...
The exact mechanism of partial clinical remission in type 1 diabetes mellitus (T1DM) has not been elucidated yet. severity the inflammation at time diagnosis may affect occurrence or duration this phase. We aimed to investigate relationship between hematological inflammatory parameters T1DM and (i) daily insulin requirement during follow-up (ii) presence period, which was determined according dose-adjusted HbA1c levels.A single-center retrospective study conducted, including children who...