A5031922638- Inflammatory Bowel Disease
- Polysaccharides and Plant Cell Walls
- Gut microbiota and health
- Regulation of Appetite and Obesity
- Diet, Metabolism, and Disease
- Microbial Metabolites in Food Biotechnology
- Food composition and properties
- Nanoparticles: synthesis and applications
- Digestive system and related health
- Celiac Disease Research and Management
- Phytochemicals and Antioxidant Activities
- Ginkgo biloba and Cashew Applications
- Moringa oleifera research and applications
- Obesity, Physical Activity, Diet
- Biochemical Analysis and Sensing Techniques
- Adipose Tissue and Metabolism
- Tea Polyphenols and Effects
- Autophagy in Disease and Therapy
- Therapeutic Uses of Natural Elements
- Heavy Metal Exposure and Toxicity
- Probiotics and Fermented Foods
- Metabolism, Diabetes, and Cancer
Warsaw University of Life Sciences
2019-2024
In overweight and obese patients, elevated serum breastmilk leptin concentrations are observed, with also being likely affected by the diet. We analyzed in normal weight (NW) overweight/obese (OW/OB) mothers, evaluated its associations (1) maternal anthropometric parameters; (2) markers of cardiometabolic health; (3) The BLOOM (Breastmilk Link to Overweight/Obesity Maternal diet) study was conducted among 40 women (n = 20 OW/OB; n 20, NW) who were exclusively or predominantly breastfeeding...
Background: Oat beta-glucans are polysaccharides, belonging to soluble fiber fraction, that show a wide spectrum of biological activity. The aim this study was evaluate the time-dependent antioxidative effect chemically pure oat beta-glucan fractions, characterized by different molar mass, which were fed animals with early stage 2,4,6-trinitrobenzene sulfonic acid (TNBS) - induced colitis. Methods: conducted on 150 adult male Sprague Dawley rats assigned two groups-healthy control (H) and...
Background: Crohn’s disease (CD) is characterized by chronic inflammation of the gastrointestinal tract with alternating periods exacerbation and remission. The aim this study was to determine time-dependent effects dietary oat beta-glucans on colon apoptosis autophagy in CD rat model. Methods: A total 150 Sprague–Dawley rats were divided into two main groups: healthy control (H) a TNBS (2,4,6-trinitrobenzosulfonic acid)-induced colitis (C) group, both including subgroups fed feed without...
Colorectal cancer (CRC) accounts for 30% of all cases worldwide and is the second leading cause cancer-related deaths. CRC develops over a long period time, in early stages, pathological changes can be mitigated through nutritional interventions using bioactive plant compounds. Our study aims to determine effect highly purified oat beta-glucan on an animal model. The was performed forty-five male Sprague-Dawley rats with azoxymethane-induced early-stage CRC, which consumed feed containing 1%...
Oat beta-glucan is one of the soluble dietary fibre fractions with a wide spectrum biological activities such as anti-inflammatory and anti-tumour properties. In present study, effect low-molar-mass oat isolate (OβGl) on level autophagy apoptosis in colorectum rats induced early stages colorectal cancer was investigated. Forty-five male Sprague-Dawley were divided into two main groups: control azoxymethane-induced early-stage carcinogenesis (CRC). Both groups three subgroups fed standard...
Factors that reduce the risk of developing colorectal cancer include biologically active substances. In our previous research, we demonstrated anti-inflammatory, immunomodulatory, and antioxidant effects oat beta-glucans in gastrointestinal disease models. The aim this study was to investigate effect an 8-week consumption a diet supplemented with low-molar-mass beta-glucan two doses on potential, inflammatory parameters, colonic metabolomic profile azoxymethane(AOM)-induced early-stage large...
Nanosilver is a popular nanomaterial, the potential influence of which on humans serious concern. Herein, we exposed male Wistar rats to two regimens: repeated oral dose 30 mg/kg bw silver nanoparticles (AgNPs) over 28 days and single-dose injection 5 AgNPs. At three different time points, assessed antioxidant defense, oxidative stress inflammatory parameters in colon, as well toxicity markers liver plasma. Both experimental scenarios showed increased inflammation colon. Oral administration...
Oat beta-glucans (OBGs) are known for their beneficial effects on gut health, including anti-inflammatory and prebiotic effects. The aim of this study was to evaluate the impact two doses (1% or 3% w/w) dietary low-molar-mass OBG supplementation colorectal cancer (CRC) development, immune cell profiles, intestinal barrier protein expression, microbiota composition in a rat model CRC induced by azoxymethane (AOM). Microbiome analysis revealed significant differences between control groups....
Crohn's disease (CD), a condition characterized by chronic inflammation of the gastrointestinal tract with alternating periods exacerbation and remission, is becoming common around world. This study aimed to analyze molecular mechanisms underlying anti-inflammatory properties oat beta-glucans varying molar masses modulating expression chemokines their receptors as well other proteins related both stages TNBS (2,4,6-trinitrobenzosulfonic acid)-induced colitis, which an animal model CD. The...
Pregnancy and lactation are associated with metabolic changes, including alterations in energy metabolism, which closely linked to body mass composition due hormonal status. Therefore, the objective of this study was investigate metabolism exclusively or predominantly breastfeeding mothers normal weight (NW) overweight/obesity (OW/OB) evaluate its associations fasting serum leptin.
Beta-glukany to polisacharydy zbudowane z jednostek D-glukozy połączonych wiązaniami beta-glikozydowymi. Związki te są obecne w różnych produktach spożywczych, takich jak zboża, grzyby, drożdże czy wodorosty. Pochodzące ze zbóż beta-glukany liniowymi polimerami dobrze rozpuszczalnymi wodzie, które wykazują szereg prozdrowotnych właściwości. W niniejszej pracy dokonano przeglądu najnowszej literatury dotyczącej korzystnego wpływu beta-glukanów obecnych zbożach na organizm ludzi i zwierząt...