AI platforms are equipped with advanced ‎algorithms that have the potential to offer a wide range of ‎applications in healthcare services. However, information about accuracy chatbots against ‎conventional drug-drug interaction tools is limited‎. This study aimed assess sensitivity, specificity, and ChatGPT-3.5, ChatGPT-4, Bing AI, Bard predicting interactions.

Immune checkpoint inhibitors, including PD-L1 (programmed death ligand-1) inhibitors have well documented anticancer therapeutic effect in most types of cancers but its use the treatment ovarian cancer is not yet proven. The aim our study to explore predictive biomarkers and association with outcomes. We investigated role expressions tumor microenvironment cells immune stem different cancer.A total 119 surgical archived samples were collected from pathology department at King Fahad...

Background and AimJordan implemented abrupt extreme lockdown measures to prevent the spread of COVID-19. This study aims evaluate effect these on paediatric patients with type 1 diabetes in terms acute metabolic complications shortages insulin glucose measuring supplies. It also evaluates caregivers' perceptions use telemedicine during lockdown.MethodsThis is a questionnaire-based cross-sectional study. was completed using Google forms patients/caregivers were asked consent if they agreed...

Background: The emergence of Chat-Generative Pre-trained Transformer (ChatGPT) by OpenAI has revolutionized AI technology, demonstrating significant potential in healthcare and pharmaceutical education, yet its real-world applicability clinical training warrants further investigation. Methods: A cross-sectional study was conducted between April May 2023 to assess PharmD students' perceptions, concerns, experiences regarding the integration ChatGPT into pharmacy education. utilized a...

This study investigated parental attitudes toward childhood vaccination in Jordan, focusing on acceptance, concerns, and perceptions. A cross-sectional survey conducted from January to February 2024 included 939 parents. Findings indicated that 85.4% (n = 802) of respondents received the COVID-19 vaccine, while only 25% 229) vaccinated their children. Concerns regarding vaccine safety efficacy were prevalent, with 63.9% 600) expressing worries about side effects 46.9% 440) trusting...

Disulfiram and hydralazine have recently been reported to anti-cancer action, repositioned be used as adjuvant in cancer therapy. Chemotherapy combined with other medications, such those that affect the immune system or epigenetic cell profile, can overcome resistance fewer adverse effects compared chemotherapy alone. In present study, a combination of doxorubicin (DOX) hydrazine (Hyd) disulfiram (Dis), triple treatment, was evaluated against wild-type DOX-resistant MCF-7 breast line. Both...

ABSTRACT Background Chronic respiratory disorders such as asthma and chronic obstructive pulmonary disease (COPD) may deteriorate into acute exacerbations requiring hospitalization. Assessing the predictors of prolonged hospital stays could help identify potential interventions to reduce burden on patients healthcare systems. Aim This study aimed risk factors attributed among admitted with in Jordan. Methods A retrospective cohort was conducted by reviewing demographic clinical...

Background/Objectives: Neonatal sepsis is a systemic inflammation in neonates caused by bacteria, viruses, or fungi that can progress into severe conditions. In developing countries, neonatal major cause of mortality and public health issue with high prevalence. This study aims to evaluate the antibiotic prescription practice resistance patterns bacterial isolates from intensive care unit (NICU) at largest governmental hospital Amman, Jordan. Methods: was retrospective cross-sectional study....

During COVID-19 pandemic in Jordan, a number of medical students participated voluntary work. However, barriers and facilitators were unclear. Therefore, we aimed to evaluate their experience attitudes towards volunteering during the factors affecting that. A cross-sectional questionnaire-based study, using paper online questionnaire which distributed final-year at University Jordan from August 2021 October 2021, about work pandemics. total 375 final year responded questionnaire. The male...

Objectives The widespread use of proton pump inhibitors (PPIs) raised concerns on the safety long-term these drugs. Community pharmacists have great responsibility educating patients drugs which requires having adequate knowledge. aim this study was to assess practices and knowledge community regarding PPIs. Design This a cross-sectional conducted by filling in questionnaire. questionnaire developed after comprehensive literature review assessed practices. Settings with at least 1 year...

The fracture risk assessment tool (FRAX®) is useful in clinical practice for assessing ten-year major osteoporotic and hip risk. This cross-sectional study aimed at possible predictors of the FRAX® score Jordanian women. Univariate multivariate linear regression analysis was used to evaluate score. A total 400 women were included study, hypertension most common medical condition, 66.3% (<i>n</i> = 265) participants did not have their vitamin D status checked, 9.0% respondents had...

This cross-sectional observational study, conducted from 01/09/2023 to 01/11/2023, involved 200 warfarin-using patients outpatient clinics assess the knowledge and understanding of warfarin among through face-to-face interviews. Almost 70% participants displayed insufficient about their therapy, potentially linked inadequate counseling or patient comprehension. The had an average weekly dose 32.9 ± 11.2, more than half used for at least 2 years. Only one third most recent INR level was...

Purpose: Breast cancer patients are subjected to many hardships during chemotherapy which negatively affects the patient's quality of life. The current study was conducted identify aspects with low scores and produce untoward effects on Results: results showed that social functioning domain achieved high life mean score 76.68 ± 32.94 while emotional attained 38.18 29.61. most apparent symptoms detected were insomnia fatigue followed by pain loss appetite. Regarding EORTC-BR45, higher better...

The coronavirus disease that emerged in 2019 (COVID-19) has affected health, societies and economies. Policies have been imposed by different countries to slow the spread of disease, including national lockdowns, curfews, border closures enforcement social distancing measures disturbed drug supply chain resulted shortages. Uncertainty concerning pandemic also led panic buying drugs stockpiling households, which amplified problem. In this cross-sectional study, a self-developed questionnaire...

Excessive exposure to unprotected sunlight increases the risk of premature skin aging and cancer. University students can be considered a high-risk group for short- long-term adverse effects ultraviolet (UV) radiation, owing their intensive sun. This study aimed evaluate university students’ knowledge practice sunscreen use in Northern Jordan. A cross-sectional was conducted using self-administered questionnaire assess practice. The created Google Forms distributed online on different social...

Objectives: This retrospective analysis was conducted to update the antibiotic sensitivity profiles of Escherichia coli (E. coli) in urinary tract infections (UTIs) among adults (≥18 years) Jordan. Methods: Data were collected from patients diagnosed with UTIs and confirmed by positive E. cultures between 1 January 2019 9 July 2021. The resistance patterns empiric antibiotics assessed matching prescribed those tested, using clinical breakpoints classify isolates as susceptible or resistant....

This research aimed to explore how telepharmacy is perceived, whether it would be willingly used by the overall population in Jordan, and associated socioeconomic disparities that might affect its acceptance.This a survey-based cross-sectional study involving general public of Jordan. The took place various Jordanian cities from May 2nd June 1st, 2023. Using Google forms, questionnaire was shared through social media channels (such as Facebook WhatsApp).The received responses 800...