A5079603179- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Head and Neck Cancer Studies
- Ultrasound Imaging and Elastography
- Radiation Dose and Imaging
- Prostate Cancer Diagnosis and Treatment
- Advances in Oncology and Radiotherapy
- Photoacoustic and Ultrasonic Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- MRI in cancer diagnosis
- Neonatal Respiratory Health Research
- AI in cancer detection
- Radiomics and Machine Learning in Medical Imaging
- Dysphagia Assessment and Management
- Effects of Radiation Exposure
- Breast Lesions and Carcinomas
- Glioma Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Digital Radiography and Breast Imaging
- Radiology practices and education
- Brain Metastases and Treatment
- Medical Imaging and Analysis
- Economic and Financial Impacts of Cancer
University College London
2023-2025
Siemens Healthcare (United States)
2024
Varian Medical Systems (United States)
2023-2024
Siemens Healthcare (Germany)
2024
University of Calgary
2014-2023
Varian Medical Systems (Canada)
2023
Society of Interventional Radiology
2023
Foothills Medical Centre
2009-2022
University of Alberta
2018
Immanuel Krankenhaus
2014
Deep inspiration breath hold (DIBH) reduces heart and left anterior descending artery (LAD) dose during left-sided breast radiation therapy (RT); however there is limited information about which patients derive the most benefit from DIBH. The primary objective of this study was to determine DIBH by comparing percent reduction in mean cardiac conferred for treated with whole RT ± boost (WBRT) versus those receiving breast/chest wall plus regional nodal irradiation, including internal mammary...
Highlights•Current treatment planning methods constrain pharyngeal constrictor mean dose.•Literature constraints classify patient-reported dysphagia below 60% accuracy.•Decision tree and feature selection method identified new clinical constraints.•Combination mid-dose perform better than literature.AbstractAimsHead neck radiotherapy long-term survival continues to improve the management of side-effects is moving forefront patient care. Dysphagia associated with dose constrictors can be...
On March 11, 2020, the World Health Organization declared COVID-19 outbreak a global pandemic. Public health officials have urged communities to minimize transmission by changing their habits, including posttravel self-isolation, increased hygiene vigilance, remote working, and social distancing.1Ferguson N.M. Laydon D. Nedjati-gilani G. et al.Impact of non-pharmaceutical interventions (NPIs) reduce mortality healthcare...
Abstract Purpose Radiotherapy delivered at ultra‐high‐dose‐rates (≥40 Gy/s), that is, FLASH, has the potential to effectively widen therapeutic window and considerably improve care of cancer patients. The underlying mechanism FLASH effect is not well understood, commercial systems capable delivering such dose rates are scarce. purpose this study was perform initial acceptance commissioning tests an electron research product for preclinical studies. Methods A linear accelerator (Clinac 23EX)...
Three intensity-modulated tangential beam radiotherapy plan types for breast cancer treatment were evaluated based on PTV homogeneity index (HI) and equivalent uniform dose (EUD), heart V30 EUD, whole lung V20 typical planning time compared to conventional 2D plans. 20 early-stage patients CT-scanned in the supine position, field extent, gantry collimator angles chosen. Four plans created each patient: conventional, dynamically wedged distribution central axial slice; forward planned IMRT;...
In gated radiotherapy, the accuracy of treatment delivery is determined by with which both imaging and beams are gated. If time delays (the between target entering/leaving region first/last image acquired or beam on/off) for systems in opposite directions, they may increase required internal volume (ITV) margin, above that indicated tolerance either system measured individually. We a gating system's delay on 3 fluoroscopy systems, linear accelerator beams, using motion phantom known...
A low-resource visually monitored deep inspiration breath-hold (VM-DIBH) technique was successfully implemented in our clinic to reduce cardiac dose left-sided breast radiotherapy. In this study, we retrospectively characterized the chest wall and heart positioning accuracy of VM-DIBH using cine portal images from 42 patients. Central position field edge in-field maximum distance (MHD) were manually measured on compared planned positions based digitally reconstructed radiographs (DRRs). An...
The clinical value of magnetic resonance (MR) imaging was prospectively evaluated in 189 patients referred for examination the brain or spine. Comparison attending physician's diagnosis, proposed treatment, and estimated prognosis before after MR indicated a substantial effect additional information provided by this study. A suspected diagnosis refined changed 16% all patients, level confidence over half cases which unchanged. In two-thirds physician that treatment altered.
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Purpose: Gated radiotherapy is used to reduce internal motion margins, escalate target dose, and limit normal tissue dose; however, its temporal accuracy limited. Beam‐on beam‐off time delays can lead treatment inefficiencies and/or geographic misses; therefore, AAPM Task Group 142 recommends verifying the of gating systems. Many groups use sinusoidal phantom for this, under tacit assumption that determining produces negligible error. The authors test this by measuring several realistic...
Abstract Background Adaptive radiation therapy ( ART ) “flags,” such as change in external body contour or relative weight loss, are widely used to identify which head and neck cancer HNC patients may benefit from replanned treatment. Despite the popularity of , few published quantitative approaches verify accuracy replan candidate identification, especially with regards simple flagging that considered current standard practice. We propose a evaluation framework, demonstrated through...
Abstract Purpose Two dose calculation algorithms are available in Varian Eclipse software: Anisotropic Analytical Algorithm ( AAA ) and Acuros External Beam AXB ). Many Eclipse‐based centers have access to ; however, a thorough understanding of how it will affect plan characteristics and, subsequently, clinical practice is necessary prior implementation. We characterized the difference breast quality between for dissemination clinicians during Methods Locoregional irradiation plans were...
Stereotactic body radiotherapy of lung cancer often makes use a static cone-beam CT (CBCT) image to localize tumor that moves during the respiratory cycle. In this work, we developed an algorithm estimate average and complete trajectory implanted fiducial marker from raw CBCT projection data. After labeling images based on breathing phase marker, was determined by backprojecting position similar phase. To approximate trajectory, 3D is estimated its in each project as point source-image ray...