Sung Hyen Lee

ORCID: 0000-0002-7886-4752
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About
Contact & Profiles
Research Areas
  • Coccidia and coccidiosis research
  • Animal Nutrition and Physiology
  • Veterinary medicine and infectious diseases
  • Food Quality and Safety Studies
  • Garlic and Onion Studies
  • Phytochemicals and Antioxidant Activities
  • Natural product bioactivities and synthesis
  • Genomics, phytochemicals, and oxidative stress
  • Phytoestrogen effects and research
  • Pharmacological Effects of Natural Compounds
  • Antimicrobial Peptides and Activities
  • Parasitic Infections and Diagnostics
  • Immune Response and Inflammation
  • Gut microbiota and health
  • Immune Cell Function and Interaction
  • NF-κB Signaling Pathways
  • Nutrition, Health and Food Behavior
  • Fungal Biology and Applications
  • Essential Oils and Antimicrobial Activity
  • Medicinal Plants and Neuroprotection
  • Ginger and Zingiberaceae research
  • Clostridium difficile and Clostridium perfringens research
  • GABA and Rice Research
  • Insect and Pesticide Research
  • Light effects on plants

Rural Development Administration
2015-2024

National Institute of Agricultural Science and Technology
2006-2024

National Academy of Agricultural Science
2009-2023

Instituto de Ciencias Agrarias
2019-2023

United States Department of Agriculture
2006-2018

Beltsville Agricultural Research Center
2006-2015

Agricultural Research Service
2006-2014

Suwon Research Institute
2014

University of Suwon
2011

Seoul National University
1997-2007

The Clostridium -related poultry disease, necrotic enteritis (NE), causes substantial economic losses on a global scale. In the present study, mixture of two plant-derived phytonutrients, Capsicum oleoresin and turmeric (XT), was evaluated for its effects local systemic immune responses using co-infection model experimental NE in commercial broilers. Chickens were fed from hatch with diet supplemented XT, or non-supplemented control diet, either uninfected orally challenged virulent Eimeria...

10.1017/s0007114512006083 article EN British Journal Of Nutrition 2013-04-09

The effects of a compound including the secondary metabolites garlic, propyl thiosulphinate (PTS) and oxide (PTSO), on in vitro vivo parameters chicken gut immunity during experimental Eimeria acervulina infection were evaluated. In assays, comprised PTSO (67 %) PTS (33 dose-dependently killed invasive E. sporozoites stimulated higher spleen cell proliferation. Broiler chickens continuously fed from hatch with PTSO/PTS compound-supplemented diet orally challenged live oocysts had increased...

10.1017/s0007114512000530 article EN British Journal Of Nutrition 2012-04-13

The effects of dietary supplementation with an organic extract Curcuma longa on systemic and local immune responses to experimental Eimeria maxima tenella infections were evaluated in commercial broiler chickens. Dietary C. enhanced coccidiosis resistance as demonstrated by increased BW gains, reduced fecal oocyst shedding, decreased gut lesions compared infected birds fed a nonsupplemented control diet. chickens longa-supplemented diet showed humoral immunity, assessed greater levels serum...

10.3382/ps.2013-03095 article EN cc-by-nc-nd Poultry Science 2013-09-17

Allium cepa L. (A. cepa) is one of the oldest cultivated plants in world. A. has been used traditional folk medicine to treat inflammatory disease several regions, such as Palestine and Serbia. peel a higher content flavonoids, quercetin, than edible parts. These flavonoids alleviate diseases. However, anti-inflammatory effects extract-obtained using various extraction methods-and their underlying mechanisms require further investigation.Although research find safe substances natural...

10.1016/j.jep.2023.116851 article EN cc-by-nc-nd Journal of Ethnopharmacology 2023-06-27

The protective effect of orally administered Curcuma longa (turmeric), Capsicum annuum and C. frutescens (hot pepper), Lentinus edodes (shiitake mushroom) on avian coccidiosis was evaluated in young broilers. Broiler chickens were continuously fed with a standard diet or supplemented Curcuma, Capsicum/Lentinus Curcuma/Capsicum/Lentinus from hatch body weight gains, fecal oocyst shedding, antibody titers, pro-inflammatory cytokine gene expression measured as parameters immunity following...

10.2141/jpsa.009025 article EN The Journal of Poultry Science 2010-01-01

This study describes a novel immunization strategy against avian coccidiosis using exosomes derived from Eimeria parasite antigen (Ag)-loaded dendritic cells (DCs). Chicken intestinal DCs were isolated and pulsed in vitro with mixture of sporozoite-extracted Ags tenella, E. maxima, acervulina, the cell-derived isolated. Chickens nonimmunized or immunized intramuscularly subsequently noninfected coinfected acervulina oocysts. Immune parameters compared among nonimmunized/noninfected,...

10.1128/iai.06413-11 article EN Infection and Immunity 2012-02-22

The effects of cinnamaldehyde (CINN) on in vitro parameters immunity and vivo protection against avian coccidiosis were evaluated. In stimulation chicken spleen lymphocytes with CINN (25–400 ng/ml) induced greater cell proliferation compared the medium control ( P < 0·001). activated cultured macrophages to produce higher levels NO at 1·2–5·0 μg/ml 0·001), inhibited growth tumour cells 0·6–2·5 0·001) reduced viability Eimeria tenella parasites 10 100 0·05 0·001, respectively), media...

10.1017/s0007114511001073 article EN British Journal Of Nutrition 2011-04-18
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