- Regulation of Appetite and Obesity
- Biochemical Analysis and Sensing Techniques
- Eating Disorders and Behaviors
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Olfactory and Sensory Function Studies
- Neurotransmitter Receptor Influence on Behavior
- Advanced Chemical Sensor Technologies
- Sleep and Wakefulness Research
- Neuroscience and Neuropharmacology Research
- melanin and skin pigmentation
- Neuroendocrine regulation and behavior
- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Apelin-related biomedical research
- Natural Compound Pharmacology Studies
- Obesity, Physical Activity, Diet
- Diet, Metabolism, and Disease
- Cholesterol and Lipid Metabolism
- Memory and Neural Mechanisms
- Biochemical effects in animals
- Thyroid Disorders and Treatments
- Research Data Management Practices
- Bariatric Surgery and Outcomes
- Neuroscience of respiration and sleep
Grinnell College
2011-2022
Association on Higher Education And Disability
2016
University of Cincinnati
2007-2009
The University of Texas Southwestern Medical Center
2007
Purdue University West Lafayette
2001-2005
Jackson Laboratory
1952
Recent studies indicate that decreased central dopamine is associated with diet-induced obesity in humans and animal models. In the current study, authors assessed hypothesis reduces mesolimbic function. Specifically, compared turnover this region between rats fed a high-fat diet those consuming standard low-fat diet. The also behavioral consequences of by testing response these animals conditioned place paradigm using amphetamine as reinforcer an operant conditioning sucrose reinforcement....
In an attempt to locate the cause which brings on convulsive seizures, agents prevent lethal seizures in DBA mouse strain, such as glucose, epinephrine and several hormonal compounds, steroids, were used. The inbred strain is characterized by its extremely high incidence of “lethal-convulsive-seizures” during adolescent period. Testing mice this period with various compounds showed that responds injections all them degrees protectiveness against, not only fatal but also total seizure...
To develop and use a behavioral paradigm for assessments of what nutrient properties are detected by intestinal chemoreceptors, we combined features the "electronic esophagus" preparation (Elizalde G Sclafani A. Physiol Behav 47: 63-77, 1990) conditioned taste aversion protocol (Garcia J Koelling RA. Psychon Sci 4: 123-124, 1966). In four experiments, separate groups food-deprived rats with gastric (experiments 1-4) or duodenal (experiment 4) catheters were infused either carbohydrates...
The intestinal taste aversion paradigm has previously demonstrated that animals could orally discriminate between carbohydrate and fat subsequent to pairing a gastrointestinal (GI) infusion of 1 nutrient with lithium chloride (LiCl), whereas they not 2 nonnutritive flavors (A. L. Tracy, R. J. Phillips, M. Chi, T. Powley, & Davidson, 2004). present experiments assessed the relative salience nutritive stimuli when presented either intestinally or orally. Two compound stimuli, each comprising...
Objective Nausea and aversive food responses are commonly reported following bariatric surgery, along with post‐surgical reduction in meal size. This study investigates whether a size limit can be conditioned by associating large meals outcomes. Methods In rats, the intake of exceeding pre‐defined threshold was paired lithium chloride‐induced gastric illness, effects on self‐determined intakes body weight were measured. Results Rats given LiCl contingent learned to reliably reduce below this...