- Electroconvulsive Therapy Studies
- Cancer survivorship and care
- Treatment of Major Depression
- Palliative Care and End-of-Life Issues
- Childhood Cancer Survivors' Quality of Life
- Bipolar Disorder and Treatment
- Dementia and Cognitive Impairment Research
- Healthcare Decision-Making and Restraints
- Schizophrenia research and treatment
- Mental Health and Psychiatry
- Pain Management and Opioid Use
- Grief, Bereavement, and Mental Health
- Religion, Spirituality, and Psychology
- Opioid Use Disorder Treatment
- Mental Health Treatment and Access
- Family Support in Illness
- Menopause: Health Impacts and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cancer-related cognitive impairment studies
- Prenatal Substance Exposure Effects
- Glioma Diagnosis and Treatment
- Estrogen and related hormone effects
- Psychosomatic Disorders and Their Treatments
- Alcoholism and Thiamine Deficiency
Mayo Clinic in Florida
2016-2025
WinnMed
2013-2025
Mayo Clinic
2014-2025
Jacksonville College
2016-2024
Mayo Clinic in Arizona
2012-2023
University of California, San Diego
2019
Lindner Center of HOPE
2018
University of Cincinnati
2009-2018
Cleveland Clinic
2013
University of Missouri–Kansas City
2013
<h3>Background</h3> Extensive literature documents personal distress among physicians and a decrease in their satisfaction with the practice of medicine over recent years. We hypothesized that who spent more time aspect work they found most meaningful would have lower risk burnout. <h3>Methods</h3> Faculty Department Internal Medicine at large academic medical center were surveyed fall 2007. The survey evaluated demographic variables, characteristics, career satisfaction. Burnout was...
Objective To compare the relative efficacy of electroconvulsive therapy (ECT) in psychotic and nonpsychotic patients with unipolar major depression. Methods The outcome an acute ECT course 253 (n = 176) 77) depression was assessed first phase ongoing National Institute Mental Health-supported four-hospital collaborative study continuation treatments after successful courses. administered bilateral electrode placement at 50% above titrated seizure threshold. remission criteria were rigorous:...
<h3>Background</h3> Although electroconvulsive therapy (ECT) has been shown to be extremely effective for the acute treatment of major depression, it never systematically assessed as a strategy relapse prevention. <h3>Objective</h3> To evaluate comparative efficacy continuation ECT (C-ECT) and combination lithium carbonate plus nortriptyline hydrochloride (C-Pharm) in prevention depressive relapse. <h3>Design</h3> Multisite, randomized, parallel design, 6-month trial performed from 1997...
PURPOSE: Hot flashes can be a prominent problem in women with history of breast cancer. Given concerns regarding the use hormonal therapies such patients, other nonhormonal means for treating hot are required. Based on anecdotal information efficacy fluoxetine and newer antidepressants flashes, present trial was developed. PATIENTS AND METHODS: This used double-blinded, randomized, two-period (4 weeks per period), cross-over methodology to study (20 mg/d) cancer or concern estrogen (because...
Article Abstract Background: Remission of illness in patients with major depressive disorder (MDD) is achieved less than half initially treated medication. Electroconvulsive therapy (ECT) another treatment option. We report the speed response and remission rates a cohort depressed who received course acute-phase ECT initial phase an ongoing multicenter randomized trial continuation versus pharmacotherapy. Method: Patients MDD according to DSM-IV criteria bilateral 3 times weekly. Prior each...
The primary goal of this study was to evaluate the feasibility and effectiveness a structured, multidisciplinary intervention targeted maintain overall quality life (QOL), which is more comprehensive than psychosocial distress, patients undergoing radiation therapy for advanced-stage cancer.Radiation with advanced cancer an estimated 5-year survival rate 0% 50% were randomly assigned either eight-session structured arm or standard care arm. eight 90-minute sessions addressed five domains QOL...
OBJECTIVE: This study assessed the incidence, severity, and course of expressed suicidal intent in depressed patients who were treated with ECT. The data are from first phase an ongoing, collaborative multicenter study, overall aim which was to compare continuation ECT pharmacotherapy prevention relapse after a successful METHOD: Suicidal intent, as by during interview, scored at baseline before each session item 3 on 24-item Hamilton Depression Rating Scale 444 unipolar depression. RESULTS:...
A past history of major depression or alcoholism has been associated with poorer smoking treatment outcomes.To evaluate the efficacy bupropion for cessation in smokers a former alcoholism, and changes depressive symptoms during abstinence.Data were drawn from multicentre trial cessation. Smokers (n = 615) received placebo sustained-release at 100, 150, 300 mg/day six weeks after target quit date (TQD). The primary outcome was point prevalence abstinence end one year. Beck Depression...
PURPOSE Hot flashes can be a prominent clinical problem for breast cancer survivors and men who undergo androgen-deprivation therapy. Anecdotal information suggested low dose of relatively new antidepressant, venlafaxine, could abrogate this problem. MATERIALS AND METHODS This study included 28 consecutive assessable patients entered onto phase II trial. flash data were collected by daily diary questionnaires during 1-week baseline period then 4 weeks, which time received venlafaxine 12.5 mg...
PURPOSE: Hot flashes can be a prominent problem in women with history of breast cancer. Given concerns regarding the use hormonal therapies such patients, other nonhormonal means for treating hot are required. Based on anecdotal information efficacy fluoxetine and newer antidepressants flashes, present trial was developed. PATIENTS AND METHODS: This used double-blinded, randomized, two-period (4 weeks per period), cross-over methodology to study (20 mg/d) cancer or concern estrogen (because...
Assessment of patient quality life (QOL) requires balancing the details provided by multi-item assessments with reduced burden single-item assessments. In this project, we investigated psychometric properties Linear Analog Scale Assessments (LASAs) for patients newly diagnosed high-grade gliomas. Measures included QOL LASAs (overall, physical, emotional, spiritual, intellectual), Symptom Distress (SDS), Profile Mood States (POMS; overall, confusion, fatigue), and Functional Cancer...
ABSTRACT OBJECTIVE: To describe the quality of life (QOL) over time for adults with newly diagnosed high-grade gliomas and to examine relationship between QOL outcome data collected in three prospective cooperative group clinical trials. METHODS: The study was a companion protocol Phase II glioma protocols. Five self-administered forms were completed by patients assess at entry, 2 months, 4 months after enrollment. RESULTS: available baseline, first, second subsequent follow-up evaluations...
Background and Purpose —Orthostatic other stresses trigger tachycardia associated with symptoms of tremulousness, shortness breath, dizziness, blurred vision, and, often, syncope. It has been suggested that paradoxical cerebral vasoconstriction during head-up tilt might be present in patients orthostatic intolerance. We chose to study middle artery (MCA) blood flow velocity (BFV) vasoregulation intolerance (OI). Methods —Beat-to-beat BFV from the MCA, heart rate, CO 2 , pressure (BP),...
The increasing prevalence of heart failure (HF) and high associated costs have spurred investigation factors leading to adverse outcomes in patients with HF. Studies date report inconsistent evidence on the link between depression only limited data emergency department outpatient visits.Olmsted, Dodge, Fillmore county, Minnesota residents HF were prospectively recruited October 2007 December 2010 completed a 1-time 9-item Patient Health Questionnaire for categorized as: none minimal (Patient...