A5038440338- Antibiotic Resistance in Bacteria
- Urinary Tract Infections Management
- Bacterial Identification and Susceptibility Testing
- Malaria Research and Control
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Use and Resistance
- Plasma Applications and Diagnostics
- Neonatal and Maternal Infections
- Pneumonia and Respiratory Infections
- Infections and bacterial resistance
- Neutropenia and Cancer Infections
- Mosquito-borne diseases and control
- Pediatric Urology and Nephrology Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Antifungal resistance and susceptibility
- Escherichia coli research studies
- Mycobacterium research and diagnosis
- Nosocomial Infections in ICU
- Infective Endocarditis Diagnosis and Management
- Vibrio bacteria research studies
- Surgical site infection prevention
- Burn Injury Management and Outcomes
- Monetary Policy and Economic Impact
- Enterobacteriaceae and Cronobacter Research
- Wound Healing and Treatments
All India Institute of Medical Sciences
2016-2025
Sickle Cell Institute Chhattisgarh, Raipur
2025
Siksha O Anusandhan University
2025
Indian Institute of Technology Delhi
2023-2024
All India Institute of Medical Sciences Raipur
2015-2024
All India Institute of Medical Sciences Bhopal
2015-2024
Creative Commons
2024
National AIDS Control Organisation
2024
Clinical and Laboratory Standards Institute
2023
Max Super Speciality Hospital
2023
Neonatal sepsis epidemiology has been adequately reported in tertiary-care hospitals. However, such data are scarce from district hospitals low-income and middle-income countries. This study aimed to evaluate the incidence of sepsis, pathogen profile, antimicrobial resistance among neonates admitted special newborn care units India. We prospectively enrolled five India between October, 2019, December, 2021. Blood cultures were obtained who met prespecified criteria processed at laboratories...
The rise in multidrug-resistant pathogens and biofilms has become a significant issue to address. In the of hour, various innovating technologies are being used combat these deadly pathogens. One emerging is cold atmospheric plasma (CAP) which could bring revolution this aspect. antimicrobial property CAP makes it powerful tool inactivation biofilms. This review paper emphasizes how efficacy affected by types devices, operating gas composition flow rate, variation source frequency, voltage...
Urinary tract infection (UTI) is one of the most common infections in clinical practice worldwide both healthcare and community settings causing significant morbidity mortality. It major conditions at level treated empirically regarded as a potential cause emergence antimicrobial resistance (AMR). Limited information available regarding community-acquired UTI (CA-UTI) from India.This first its kind, multicentric-cross-sectional study targeting patients attending out-patient department (OPD)...
The rise in multidrug-resistant (MDR) ESKAPE bacteria have become a major therapeutic challenge globally. Recently, novel cold atmospheric pressure plasma (CAP) as an antimicrobial is becoming popular. In this study, indigenously developed AC CAP jet (CAPJ) fed with argon gas was used to evaluate its efficacy on these isolated from clinical specimens, such urine, blood, and sputum tertiary care hospital India. difference CAP's activity Gram-negative bacilli (MDR E. coli) Gram-positive cocci...
Evidence-based prescribing is essential to optimise patient outcomes in cystitis. This requires knowledge of local antibiotic resistance rates. DASH Protect Antibiotics (https://dashuti.com/) a multicentric mentorship programme guiding centres preparing, analysing and disseminating antibiograms promote antimicrobial stewardship community UTI. Here we map the susceptibility profile Escherichia coli from 22 Indian centres. These spanned 10 States three Union Territories. Antibiograms for...
The authors aimed to evaluate the antimicrobial susceptibility pattern of Acinetobacter isolates responsible for nosocomial meningitis/ventriculitis in neurosurgical ICU. also sought identify risk factors mortality following meningitis/ventriculitis.This was a retrospective study 72 patients admitted ICU between January 2014 and December 2018 with clinical microbiological diagnosis postneurosurgical baumanii meningitis/ventriculitis. Electronic medical data on characteristics, underlying...
Purpose: Elizabethkingia is an emerging non-fermenting Gram-negative bacillus (NFGNB) causing bloodstream infections (BSI) associated with high mortality. It demonstrates a unique antimicrobial profile in showing susceptibility to antimicrobials effective against Gram-positive bacteria. This study was undertaken determine the overall frequency of BSI, risk factors, microbiological susceptibility, and clonal relationship isolates using Enterobacterial Repetitive Intergenic Consensus...
Abstract Background Catheter-related bloodstream infections (CRBSIs) affect approximately 3 to 27% of patients. As per IDSA (2009) criteria, concordant organisms from blood and catheter tip cultures, or specific criteria met by two samples are required for CRBSI diagnosis. Catheter cultures necessitate removal the line entail increased healthcare costs. Emerging evidence questions reliability this labor-intensive practice in diagnosing CRBSI. We aimed determine utility at our Institute....
Abstract Background Early detection of carbapenem-resistant gram negative bacilli(CR-GNB) is critical in patients with sepsis. Delay diagnosis leads to higher mortality. We evaluated the performance Xpert® Carba-R assay (Cepheid, Sunnyvale, CA, USA) directly on flagged blood culture samples sepsis.Fig 1:Workflow Methods Patients suspected sepsis GNB were recruited. was performed positive sample. Their diagnostic compared and drug susceptibility testing (DST)(VITEK-2) time results noted...
Knowledge of local antibiotic susceptibility rates is essential to strengthen antimicrobial stewardship programs. DASH Protect Antibiotics (https://dashuti.com/), promotes the dissemination focused antibiograms in community urinary tract infection (UTI). This study mapped profile Klebsiella pneumoniae from 18 Indian centers. The centers spanned nine States and three Union Territories. Urinary K. outpatient clinic were collated analyzed. Standardization was achieved through online training....
Abstract Curcumin, a bioactive compound derived from Curcuma longa, has shown promising potential in breast cancer therapy due to its multitarget pharmacological effects. This study aimed explore the molecular mechanisms underlying curcumin's anticancer activity using an integrative computational approach, including predictive modeling, docking, and pathway enrichment analysis. Curcumin demonstrated strong binding affinities critical targets such as matrix metalloproteinase-9 (MMP9), protein...
This study evaluated the effectiveness of ceftazidime-avibactam (CZA) alone and in combination with aztreonam (ATM) against 50 extensively drug-resistant (XDR) Gram-negative bacteria (GNB) isolates using disk stacking method. New Delhi metallo-beta-lactamase (NDM) was predominant carbapenemase, detected 50% showing synergy. The CZA-ATM demonstrated synergy 40% isolates, 75% patients receiving this achieving microbiological clearance. simple, rapid testing method can guide effective...
Background: Globally, urinary tract infections (UTIs) have attracted the attention of clinicians and become a serious public health threat. Management UTIs has growing concern for due to increased antimicrobial resistance (AMR). The present study was conducted identify most diagnosed uropathogens causing among Inpatient Department (IPD) Outpatient (OPD) patients visiting tertiary care centre also analyse patterns prescribed antibiotics based on physicians’ empirical urine culture-based...
Increasing occurrence of infections caused by multidrug-resistant Gram-negative bacteria resulted in colistin being the last agent for treatment. Apart from plasmid-mediated mcr genes, mutations involving several genes like mgrB, phoP/phoQ, pmrA, pmrB, pmrC, and crrABC are leading causes resistance. Four susceptibility testing methods were compared against broth microdilution (BMD) determined presence mcr1-5 gene.A total 100 carbapenem-resistant Enterobacterales isolates tested commercial...
Hypervirulent Klebsiella pneumoniae (hvKp) is a hypermucoviscous phenotype of classical (cKp) that causes serious infections in the community. The recent emergence multidrug-resistant hvKp isolates (producing extended-spectrum beta-lactamases and carbapenemases) along with other virulence factors health care settings has become clinical crisis. Here, we aimed to compare distribution determinants antimicrobial resistance (AMR) genes relation various sequence types (STs) among from both...
Abstract The emergence of antimicrobial resistance has become a major contributor to healthcare-associated infections. Recently, the cold atmospheric pressure plasma jet (CAPJ) discharges have garnered attention researchers globally for their novel property. This research evaluated effectiveness an in-house developed CAPJ on inactivation multidrug-resistant (MDR) E. coli and S. aureus artificially inoculated over stainless steel aluminium test surfaces. A greater than ∼5 log 10 reduction ,...
In this report, we present a case of rhino-orbital mucormycosis in 57-year-old female with poorly controlled diabetes mellitus. The only mold cultured at 25°C, 37°C, and 40°C from specimen the nasal crust was identified phenotypically independently using nuclear ribosomal DNA sequence data as Thamnostylum lucknowense. To our knowledge, report presents first implicating mucoraceous fungus mycotic agent human infection.