Hypothyroidism is a common and well recognized cause of diffuse hair loss. Zinc other trace elements such as copper selenium are required for the synthesis thyroid hormones, deficiency these can result in hypothyroidism. Conversely, hormones essential absorption zinc, hence hypothyroidism acquired zinc deficiency. The loss attributed to may not improve with thyroxine unless supplements added, demonstrated our case.

Drug reaction with eosinphilia and systemic symptoms (DRESS) drug-induced hypersensitivity syndrome (DiHS) represent the same spectrum of a drug reaction.To compare clinical profile patients diagnosed as definite/probable DRESS by Registry Severe Cutaneous Adverse Reaction (RegiSCAR) scoring system atypical DiHS Japanese consensus group criteria.We did retrospective study in tertiary referral center.We included who satisfied criteria for and/or received inpatient care our department from...

Drug eruptions range from transient erythema to the life threatening severe cutaneous adverse reactions (SCAR) that encompass Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP) and drug reaction with eosinophilia systemic symptoms complex (DRESS).To study clinical epidemiological aspects of (CADR).Ethical clearance was obtained institutional ethics committee. All patients admitted in Dermatology ward our tertiary care hospital...

Abstract Drug reaction with eosinophilia and systemic symptoms ( DRESS ) is a severe adverse drug that can affect any age group. We carried out prospective study of the clinicoepidemiologic aspects in children. prospectively studied all patients ages 12 years younger admitted to departments pediatrics dermatology at tertiary care hospital over 3‐year period probable or definite , defined based on Regi SCAR scoring system. A total 11 were studied. Lamotrigine (four patients) pencillins (three...

Background: Detection of peripheral nerve thickening and function impairment is crucial in the diagnosis management leprosy. Aims objectives: (1) To document cross-sectional area, echotexture blood flow nerves healthy controls leprosy cases using high-resolution ultrasound, (2) to compare sensitivities clinical examination ultrasound detecting Methods: Peripheral 30 patients age- sex-matched were evaluated clinically by ultrasound. When area a on patient was more than calculated upper bound...

<br><b>Background:</b> With the declared elimination of leprosy as a public health problem, World Health Organization has shifted focus on disabilities and deformities associated with leprosy. <b>Aims:</b> The aim was to study Grade 1 2 disability among newly diagnosed patients. <b>Materials Methods:</b> All patients attending Outpatient Department Government Medical College, Kozhikode, from January 1, 2013 December 31, were included in observed analyzed. <b>Results:</b> During 1-year...

Abstract Background Chikungunya (CHIK) is an emerging viral disease with a myriad of cutaneous manifestations. Aims The aim our study was to document the morphology and evolution skin lesions in cases presenting fever, purpuric macules vesiculobullous lesions, confirm its causative relationship CHIK, investigate further order delineate possible mechanisms bulla formation these cases. Materials Methods A prospective, descriptive hospital‐based carried out at tertiary health care centre...

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe drug which can mimic viral infection, an autoimmune disease or neoplastic disease.To study the clinical epidemiological aspects of DRESS to identify precipitating drugs.All patients admitted dermatology ward our tertiary care hospital from 1 st October 2010 30 th September 2013 probable definite as per RegiSCAR scoring system were included in this prospective study. The manifestations observed population studied common...

Objective: To assess the profile and describe clinical presentations complications of childhood leprosy in a tertiary care hospital North Kerala, South India during 2003–2012 to analyse any change age-sex pattern children below age 15 years over 10-year study period. Design: A retrospective descriptive less than diagnosed with registered for treatment institution from 2003 2012. Demographic, clinical, investigative data were collected using pre-set proforma. Results: 138 (12.1%) total 1143...

1. To study and compare the clinical histological features of Type 1 2 lepra reactions. 2. document patterns reactions observed in population.Two year cross sectional study. Patients attending outpatient department our tertiary care hospital, during period with evidence (T1R) or (T2R) were included this after obtaining written informed consent. During 34 T1R patients 14 T2R attended hospital. Biopsies taken from reacting skin lesions all studied.Dermal intragranuloma oedema was evident 50%...

Pyoderma gangrenosum is a neutrophilic dermatosis of unknown etiology, with inconstant systemic associations and variable prognosis.To study the clinical features pyoderma its response to treatment.All patients diagnosed have at dermatology department Government Medical College, Kozhikode, from January 01, 2005 December 31, 2014 were included in this prospective study.During 10-year period, 61 gangrenosum. A male predilection was noted. The most common type ulcerative (90.2%). More than 60%...

Pure neuritic leprosy is a risk factor for grade 2 disability owing to the early nerve damage.To study clinical patterns of leprosy, determine percentage patients manifesting at time diagnosis and identify any factors same.Retrospective descriptive from previous case records pure who attended tertiary centre 1st July 2007 30th June 2017.Data on satisfied World Health Organization (WHO) cardinal criteria had no skin lesion acid-fast bacilli negative status smears were collected using pre-set...

ABSTRACT Touraine Solente Gole syndrome is a rare hereditary of primary pachydermoperiostosis, with the characteristic triad pachydermia (or elephant like skin), periostosis and acropachia. A 27-year-old patient presented aesthetic deformity forehead due to deep skin folds coarsening facial features progressive thickening skin. Associated palmoplantar hyperkeratosis broadened finger toe tips digital clubbing were noticed. Dermatologic evaluation revealed cutis verticis gyrata scalp,...

Drug reaction with eosinophilia and systemic symptoms is an outcome of a complex interaction between specific drugs, certain herpesviruse types the immune system affected individual characterized by unpredictable course recurrent flares even after withdrawal offending drug administration steroids.To identify predictors disease severity in symptoms.After obtaining ethical clearance from institutional ethics committee written informed consent study participant, first hundred patients who...

Pigmented purpuric dermatoses (PPD), a group of vascular disorders with variable clinical picture is reported in all races and age groups male predilection. There are reports mycosis fungoides manifesting as pigmented purpura well progression PPD to cutaneous T-cell lymphoma. The diagnostic dilemma compounded by histological similarity fungoides. Currently, it believed that monoclonal population more likely progress malignancy. We report 31-year-old patient who presented the lichenoid...

Palmoplantar psoriasis is often disabling and refractory to conventional therapy. Systemic drugs are indicated in its severe form, but side effects a concern with their use. Methotrexate one such systemic drug which effective cheap. To reduce toxicity, methotrexate has been tried topically results have inconsistent due poor penetration into the skin by passive diffusion. Iontophoresis may enhance absorption efficacy.To evaluate efficacy safety of topical iontophoresis comparison coal tar...

Cutaneous pseudolymphomas are benign lymphoproliferative processes mimicking lymphomas clinically and histologically. One of the precipitating factors for pseudolymphoma is drugs like anticonvulsants, antidepressants angiotensin-converting enzyme inhibitors. According to existing literature phenytoin-induced cutaneous usually T-cell predominant. Most often withdrawal drug with or without short-course systemic steroids can attain a cure. Rarely malignant transformation has been reported years...

The data on the histology of cutaneous lesions drug reaction with eosinophilia and systemic symptoms (DRESS) is limited.To study histopathology to identify any features diagnostic or prognostic significance.All patients admitted dermatology ward government medical college, Kozhikode from January 1, 2014 December 31, probable definite DRESS as per RegiSCAR scoring system who were willing undergo skin biopsy included in this prospective study.The population comprised nine patients. consistent...

Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is an adverse drug reaction which has been reported to be caused by various drugs. In this report, we describe a case induced ranitidine, not previously cause SDRIFE.<br>

Microcirculation in the skin of psoriasis patients significantly differs from unaffected individuals. Vascular changes precede lesions and occur even nonlesional skin.The primary aim this work was to study nailfold capillary patients, compare it with that controls. The secondary without nail changes.A comparative cross-sectional 40 age sex-matched controls analyzed capillaries proximal all fingers using a dermoscope. mean loop density/mm, tortuous capillaries, hemorrhages, avascular areas...