A5086436771- Vector-borne infectious diseases
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Vector-Borne Animal Diseases
- COVID-19 diagnosis using AI
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Zoonotic diseases and public health
- Autophagy in Disease and Therapy
- Insect symbiosis and bacterial influences
- Study of Mite Species
- Insect Pest Control Strategies
- Yersinia bacterium, plague, ectoparasites research
- Insect Utilization and Effects
Connecticut Agricultural Experiment Station
2020-2025
Experimental Station
2021
Aedes aegypti is a highly efficient vector for numerous pathogenic arboviruses including dengue virus (DENV), Zika virus, and yellow fever virus. This efficiency can in part be attributed to their frequent feeding behavior. We previously found that acquisition of second, full, non-infectious blood meal could accelerate dissemination within the mosquito by temporarily compromising midgut basal lamina integrity; however, wild, mosquitoes are often interrupted during only acquire partial or...
Abstract We assessed the relationship between municipality COVID-19 case rates and SARS-CoV-2 concentrations in primary sludge of corresponding wastewater treatment facilities. Over 1700 daily samples were collected from six facilities with catchments serving 18 cities towns State Connecticut, USA. Samples analyzed for RNA during a 10 month time period that overlapped October 2020 winter/spring 2021 outbreaks each municipality. fit lagged regression models to estimate reported municipalities...
Macroautophagy is an evolutionarily conserved cellular process critical for maintaining homeostasis. It can additionally function as innate immune response to viral infection has been demonstrated a number of arthropod-borne (arbo-) viruses. Arboviruses are maintained in transmission cycle between vertebrate hosts and invertebrate vectors yet the majority studies assessing autophagy-arbovirus interactions have limited mammalian host. Therefore we evaluated role autophagy during arbovirus...
Tick-borne diseases continue to threaten human health across the United States. Both active and passive tick surveillance can complement case surveillance, providing spatio-temporal information on when where humans are at risk for encounters with ticks tick-borne pathogens. However, little work has been done assess concordance of acarological metrics from each method. We used data Ixodes scapularis its associated pathogens Connecticut (2019–2021) collected through collections (drag sampling)...
<title>Abstract</title> <bold>Context.</bold> As cities seek to provide more habitat for wildlife, there may be unintended consequences of increasing tick-borne disease hazards. In the United States, Northeast is both highly urban and a hotspot blacklegged ticks (<italic>Ixodes scapularis</italic>) emergence. Though was once considered suburban rural problem, hazards in landscapes are increasing.<bold>Objectives.</bold> We hypothesized that multi-scale ecological processes hierarchically...
Abstract Anaplasmosis is a vector-borne disease caused by the bacterium Anaplasma phagocytophilum and vectored Ixodes scapularis ticks primarily in northeastern United States. The Connecticut Department of Public Health designated anaplasmosis state-wide reportable 2008 large increase cases was witnessed between 2014 2019. This study used clinical reported to A. prevalence data questing I. understand emerging geographic hotspots evaluate potential association human infections. Human...
Informed by passive tick surveillance, we collected questing Haemaphysalis longicornis ticks from southwestern Connecticut, USA. Of 445 tested PCR, 3 nymphs were positive: 1 for Ehrlichia chaffeensis and 2 Borrelia burgdorferi. This finding highlights the enduring public health challenges of invasive associated pathogens.
Abstract Background Powassan virus (POWV; genus Flavivirus ) is the sole North American member of tick-borne encephalitis sero-complex and an increasing public health threat in USA. Maintained nature by Ixodes spp. ticks, POWV has also been isolated from species other hard tick genera, yet it unclear if these can serve as vectors. Dermacentor variabilis Amblyomma americanum share geographic ecologic overlap with ticks transmission foci, raising possibility that could become established...
Abstract Background The incidence of tick-borne diseases is increasing across the USA, with cases concentrated in northeastern and midwestern regions country. Ixodes scapularis one most important disease vectors has spread throughout USA over past four decades, established populations all states region. Methods To better understand rapid expansion I. pathogens they transmit, we aggregated analyzed abundance pathogen prevalence data from including Connecticut, Maine, New Hampshire, York...
Abstract We assessed the relationship between municipality COVID-19 case rates and SARS-CoV-2 concentrations in primary sludge of corresponding wastewater treatment facilities. Over 1,000 daily samples were collected from six facilities with catchments serving 18 cities towns State Connecticut, USA. Samples analyzed for RNA during a six-month time period that overlapped fall 2020 winter 2021 outbreaks each municipality. fit single regression model to estimate reported municipalities Results...