A5036845953- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Infective Endocarditis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Hemodynamic Monitoring and Therapy
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Ultrasound in Clinical Applications
- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Cardiac pacing and defibrillation studies
- Enhanced Recovery After Surgery
- Hip and Femur Fractures
- Aortic aneurysm repair treatments
- Pulmonary Hypertension Research and Treatments
- Surgical Simulation and Training
- Cardiac Arrhythmias and Treatments
- Orthopedic Surgery and Rehabilitation
Leipzig Heart Institute
2016-2025
Leipzig University
2010-2024
Deutsches Herzzentrum der Charité
2009-2024
Intensive Care Foundation
2020
Helios Kliniken
2017
University of Cape Town
2013
Kerckhoff Klinik
2012
Heinrich Heine University Düsseldorf
2012
Fraunhofer Institute for Applied Information Technology
2006
Helios Park-Klinikum Leipzig
2002
Enhanced Recovery After Surgery (ERAS) programs have been shown to lessen surgical insult, promote recovery, and improve postoperative clinical outcomes across a number of specialty operations. A core tenet ERAS involves the provision protocolized evidence-based perioperative interventions. Given both growing enthusiasm for applying principles cardiac surgery broad scope relevant interventions, an international, multidisciplinary expert panel was assembled derive list potential program...
ObjectiveAortic surgical procedures requiring hypothermic circulatory arrest are associated with altered hemostasis and increased bleeding. In a randomized clinical trial, we evaluated effects of thromboelastometrically guided algorithm on transfusion requirements.MethodsFifty-six consecutive patients (25 acute type A dissection) undergoing aortic surgery were enrolled in trial during 6-month period. Patients randomly allocated to treatment group (n = 27) or control 29) routine practices...
To evaluate the outcome of transapical aortic valve implantation (TA-AVI) in comparison to conventional surgery. One hundred consecutive high-risk patients with symptomatic stenosis received TA-AVI using Edwards SAPIEN™ pericardial xenograft between February 2006 and January 2008. Patient age was 82.7 ± 5 years, 77 were females, logistic EuroSCORE predicted risk mortality 29.4 13% Society Thoracic Surgeons score for 15.2 8.3%. Propensity analysis used identify a control group that underwent...
Background: In clinical practice, local anesthesia with conscious sedation (CS) is performed in roughly 50% of patients undergoing transcatheter aortic valve replacement. However, no randomized data assessing the safety and efficacy CS versus general (GA) are available. Methods: The SOLVE-TAVI (Comparison Second-Generation Self-Expandable Versus Balloon-Expandable Valves General Local Anesthesia Transcatheter Aortic Valve Implantation) trial a multicenter, open-label, 2×2 factorial, 447...
Background The authors compared the safety and efficacy of a newly developed fast-track concept at their center, including implementation direct admission postanesthetic care unit, to standard perioperative management. Methods All patients treated within first 6 months our unit were matched via propensity scores with historical control group who underwent cardiac surgery prior implementation. Results A total 421 successfully patients. two groups had similar age (64 +/- 13 vs. 64 12 yr for...
Fast-track treatment in cardiac surgery has become the global standard of care. We compared efficacy and safety a specialised post-anaesthetic care unit (PACU) to conventional intensive (ICU) achieving defined fast-track end-points adult patients after elective surgery.In prospective, single blinded, randomized study, 200 undergoing (coronary artery bypass graft (CABG), valve or combined CABG surgery), were selected receive their postoperative either ICU (n = 100), PACU 100). Patients who,...
Transcatheter aortic valve implantation (TAVI) using the Medtronic CoreValve (MCV) system might represent an alternative to conventional redo surgery in older high-risk patients with a failing bioprosthesis.Symptomatic bioprosthesis, aged ≥65 years logistic EuroSCORE ≥10 % were considered for treatment. Local anesthesia was used retrogradely implant MCV into bioprosthetic valve. Clinical events recorded and transthoracic echocardiography performed evaluate impact of on hemodynamics after...
The aim of this study was to analyse the feasibility, safety and effectiveness tricuspid valve (TV) repair using MitraClip system in patients at high surgical risk.Forty-two elderly high-risk (76.8±7.3 years, EuroSCORE II 8.1±5.7) with isolated TR or combined mitral regurgitation (MR) underwent edge-to-edge TV (n=11) (n=31). Procedural details, success rate, impact on severity predictors 30-day follow-up were analysed. Successful achieved 35/42 (83%, 68 clips total, 94% anteroseptal...