- Cancer, Hypoxia, and Metabolism
- Cellular Mechanics and Interactions
- Caveolin-1 and cellular processes
- ATP Synthase and ATPases Research
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Metabolomics and Mass Spectrometry Studies
- Bone Tissue Engineering Materials
- interferon and immune responses
- RNA Research and Splicing
- Cancer Research and Treatments
- Cytokine Signaling Pathways and Interactions
- Environmental Toxicology and Ecotoxicology
- Traditional Chinese Medicine Analysis
- Kruppel-like factors research
- Bone Metabolism and Diseases
- Ginseng Biological Effects and Applications
- Geophysics and Gravity Measurements
- Pharmacological Effects of Medicinal Plants
- earthquake and tectonic studies
- Mycotoxins in Agriculture and Food
- Chemokine receptors and signaling
- Glutathione Transferases and Polymorphisms
- GNSS positioning and interference
- Cancer Cells and Metastasis
Second Hospital of Shandong University
2024
Liaocheng People's Hospital
2021-2024
University of Electronic Science and Technology of China
2016-2023
Tongliao Academy of Agricultural Sciences
2023
Sichuan Cancer Hospital
2023
Stiffening of the extracellular matrix (ECM) is considered a typical remolding microenvironment in multistep tumor progression. However, molecular mechanisms by which cell responds to ECM mechanical cues remain elusive. Here, we demonstrated that microRNA-29b (miR-29b) and its downstream signaling play critical regulatory roles osteosarcoma cells sense stiffness maintain cancer stem cell-like ability. Polyacrylamide gels with 7, 20, 55 kPa were used mimic rigidity connective tissue, muscle...
Background. To study the effects of z-guggulsterone on gastric cancer cell apoptosis and mechanism related. Materials Methods. Human tumor SGC-7901 cells GES-1 normal epithelial were treated with (0–75 μM) for 24 h. MTT assay was applied to evaluate proliferation. Flow cytometry Hoechst staining used assess apoptosis. Western blotting FXR, small heterodimer partner (SHP), Bcl-2, Bax protein expression. ELISA gain levels active caspase-3 contents TNF-α, TGF-β1, VEGF. Results. The expression...
MicroRNAs (miRNAs) regulate gene expression and play a critical role in cancer physiology. However, there is still limited understanding of the function regulatory mechanism miRNAs gastric (GC).
To investigate the expression of elicitin response protein and alpha-chemokines in lung cancer, inflammatory tissues normal to observe relationship between age, sex, tumor type, stage, differentiation vascular endothelial growth factor. detect chemokines squamous cell carcinoma, adenocarcinoma small cancer analyze gender, pathological grade stage. The high rate was higher than that tissue difference statistically significant (p<0.05). different types (p<0.001). alphachemokines independent...