- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Gastrointestinal motility and disorders
- Helicobacter pylori-related gastroenterology studies
- Esophageal and GI Pathology
- Dysphagia Assessment and Management
- Congenital gastrointestinal and neural anomalies
- Pelvic floor disorders treatments
- Microscopic Colitis
- Diet and metabolism studies
- Digestive system and related health
- Celiac Disease Research and Management
- Child Nutrition and Feeding Issues
- Microbial Metabolites in Food Biotechnology
- Diverticular Disease and Complications
- Anorectal Disease Treatments and Outcomes
- Gut microbiota and health
- Therapeutic Uses of Natural Elements
- Esophageal Cancer Research and Treatment
- Inflammatory Bowel Disease
- Gastrointestinal disorders and treatments
- Intestinal and Peritoneal Adhesions
- Respiratory and Cough-Related Research
- Cardiovascular Syncope and Autonomic Disorders
- Food composition and properties
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2016-2025
University Gastroenterology
2023
Augusta University
2012-2021
University of Iowa Hospitals and Clinics
2021
Universidad Nacional Autónoma de México
2009-2020
Georgia Regents Medical Center
2013-2015
Augusta University Health
2012
Summary Background Whether intestinal dysmotility and the use of a proton pump inhibitor (PPI) either independently or together contributes to small bacterial overgrowth ( SIBO ), and/or fungal SIFO ) is not known. Aim To investigate role PPI in patients with persistent gastrointestinal complaints. Methods Patients unexplained symptoms negative endoscopy/radiology tests completed validated symptom questionnaire underwent 24‐h ambulatory antro‐duodeno‐jejunal manometry (ADJM). Simultaneously,...
Idiopathic achalasia is a disease of unknown etiology. The loss myenteric plexus associated with inflammatory infiltrates and autoantibodies support the hypothesis an autoimmune mechanism. Thirty-two patients diagnosed by high-resolution manometry were included. Twenty-six specimens from lower esophageal sphincter muscle compared 5 esophagectomy biopsies (control). Immunohistochemical (biopsies) flow cytometry (peripheral blood) analyses performed. Circulating anti-myenteric evaluated...
Background: The term ‘laryngopharyngeal reflux’ (‘LPR’) is frequently applied to aerodigestive symptoms despite lack of objective reflux evidence. This initiative aimed develop a modern care paradigm for LPR supported by otolaryngology and gastroenterology disciplines. Methods: A 28-member international inter-disciplinary working group developed practical statements within the following domains: definition/terminology, initial diagnostic evaluation, monitoring, therapeutic trials, behavioral...
Abstract Esophageal hypomotility disorders manifest with abnormal esophageal body contraction vigor, breaks in peristaltic integrity, or failure of peristalsis the context normal lower sphincter relaxation on high‐resolution manometry (HRM). The Chicago Classification version 4.0 recognizes two disorders, ineffective motility (IEM) and absent contractility, while fragmented has been incorporated into IEM definition. Updated criteria for swallows consist weak vigor measured using distal...
Abstract Background The clinical significance of colorectal sensorimotor evaluation in patients with slow transit constipation ( STC ) is unclear. We investigated whether colonic manometric useful for characterizing dysfunction and guiding therapy . Methods 24‐h ambulatory manometry was performed 80 (70 females) by placing a six sensor solid‐state probe, along assessment sensation barostat. Anorectal also performed. Manometrically, were categorized as having neuropathy or myopathy based on...
Fibre supplements are useful, but whether a plum-derived mixed fibre that contains both soluble and insoluble improves constipation is unknown.To investigate the efficacy tolerability of soluble/insoluble vs. psyllium in randomized double-blind controlled trial.Constipated patients (Rome III) received or psyllium, 5 g b.d., for 4 weeks. Daily symptoms stool habit were assessed using diary. Subjects with ≥1 complete spontaneous bowel movement/week above baseline ≥2/4 weeks considered...
Abstract Background and Aim Idiopathic achalasia is a rare esophageal motor disorder. The disease state manifests local systemic inflammation, it appears that an autoimmune component specific autoantibodies participate in the pathogenesis. study aims to determine prevalence of chronic inflammatory diseases patients with compare results those from gastroesophageal reflux (GERD). Methods It was cross‐sectional included 114 idiopathic age‐matched sex‐matched control GERD. Data on presence...
BACKGROUND: Neurologic dysfunction causes fecal incontinence, but current techniques for its assessment are limited and controversial. OBJECTIVE: The purpose of this work was to investigate spino-rectal spino-anal motor-evoked potentials simultaneously using lumbar sacral magnetic stimulation in subjects with incontinence healthy compare pudendal nerve terminal motor latency incontinence. DESIGN: This a prospective, observational study. SETTINGS: study took place 2 tertiary care centers....
Achalasia is an autoimmune disease whose probable causal agent a neurotropic virus that chronically infects the myenteric plexus of esophagus and induces in genetically susceptible host. The association between achalasia coronaviruses has not been reported.To evaluate presence SARS-CoV-2 virus, ACE2 expression, tissue architecture, immune response lower esophageal sphincter muscle (LESm) patients who posteriorly had (achalasia-COVID-19) infection before laparoscopic Heller myotomy (LHM)...
<title>Abstract</title> <bold>Background. </bold>Current studies demonstrate red blood cell distribution width (RDW) as a possible surrogate inflammation biomarker. <bold>Aim.</bold> To determine RDW in achalasia patients, compare it to GERD and healthy donor groups, evaluate its clinical relevance. <bold>Methods</bold>. It was an ambispective study. One hundred sixty-one achalasia, 161 gastroesophageal reflux disease (GERD) 500 donors (HD) were included followed up 5 years. The patient...
ABSTRACT Background Laryngopharyngeal reflux symptoms (LPS) are often attributed to gastroesophageal disease (GERD), yet objective testing confirms GERD in only a small subset of patients. The COuGH RefluX score, previously validated North American and Taiwanese populations, offers non‐invasive method stratify likelihood patients with LPS. This study aimed evaluate its performance real‐world Hispano‐American cohort. Methods We performed multicenter, retrospective cohort 459 adult from seven...
Significant advances have been made in the knowledge and understanding of epidemiology, pathophysiology, diagnosis, treatment chronic constipation, since publication 2011 guidelines on constipation diagnosis Mexico from Asociación Mexicana de Gastroenterología. To present a consensus review current state about providing updated information integrating new scientific evidence. Three general coordinators reviewed literature published within time frame January 2017. From that information, 62...
La enfermedad por reflujo gastroesofágico (ERGE) es muy prevalente en la población general, se presenta con un amplio espectro de manifestaciones clínicas que requiere diagnóstico y tratamiento precisión. Esta una revisión expertos establece recomendaciones buena práctica clínica para el personalizado ERGE. Las generaron grupo ERGE, miembros Asociación Mexicana Gastroenterología (AMG), después hacer extensa literatura publicada discutir cada recomendación reunión presencial. Este documento...