- Liver Disease Diagnosis and Treatment
- Genetic Mapping and Diversity in Plants and Animals
- Acute Lymphoblastic Leukemia research
- Genetic and phenotypic traits in livestock
- Phytochemicals and Antioxidant Activities
- Microencapsulation and Drying Processes
- Cholinesterase and Neurodegenerative Diseases
- Free Radicals and Antioxidants
- Brain Tumor Detection and Classification
- Veterinary Medicine and Surgery
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Fermentation and Sensory Analysis
- Intestinal Malrotation and Obstruction Disorders
- Forensic Anthropology and Bioarchaeology Studies
- Appendicitis Diagnosis and Management
- Cancer therapeutics and mechanisms
- Dermatoglyphics and Human Traits
- Quinazolinone synthesis and applications
- Herbal Medicine Research Studies
- Natural Products and Biological Research
- Cancer-related molecular mechanisms research
- Genomics, phytochemicals, and oxidative stress
- Phosphorus compounds and reactions
- Mast cells and histamine
- Vitamin C and Antioxidants Research
October 6 University
2019-2024
Ain Shams University
2003-2024
Deakin University
2022
Alexandria University
2022
Cairo University
2012
The instability of anthocyanins limits their application in food supplementation and the industry. Stabilities strawberry (AN) were improved by complexation with both β-CD starch against heat, H2O2, light, UV irradiation. stability AN H2O2 (2.21 mM) dropped (<20%) 6 h but was enhanced (49.32%) (96.84%) complexes. Under light conditions, solid solution (3.88 g/100 mL) forms degraded to 36.49 11.11%, while complexes displayed stabilities 98.20 91.76%, respectively, after 60 days. irradiation,...
Background: Vitamin D deficiency is a prevalent condition among critically ill patients. Information about the relationship between vitamin levels and outcomes in intensive care unit (ICU) sparse. Purpose: To evaluate status patients its relevance to severity of illness, ICU stay period, mortality. Methods: This prospective multicenter study was conducted ICUs Fayoum, Cairo, Alazhar, Ain Shams university hospitals. All were subjected interview questionnaire, laboratory investigation, level...
Background Fibromyalgia (FM) is characterized by musculoskeletal pain, fatigue, sleep and memory disturbance. There no definitive cure yet for FM-related health problems. Peroxisome proliferator-activated receptor's (PPAR's) activation associated with insulin sensitisation improved glucose metabolism. PPAR-γ was reported to alleviate FM allodynia. Limited data are discussing its effect on motor disorders.Objective To investigate the potential of agonists (pioglitazone, as one member...
Data on 813 lactating Egyptian buffaloes were used to test association between nine microsatellite DNA markers located buffalo chromosome 7. recorded from May 2009 until April 2010.For each cow the monthly test-day records of milk, fat, protein and lactose yields available.A total 5344 for trait in analysis, had at least five records.Number genotyped animals ranged 179 471.Single-trait random regression models analyze daily yields.The Wilmink's function was fit genetic effects associated...
Introduction Chronic myeloid leukemia (CML) is characterized by the presence of BCR-ABL fusion gene with constitutive tyrosine kinase activity that activates many signaling pathways contributing to abnormal growth and survival leukemic cells. Basophilia a strong independent prognostic variable correlates phase CML. In CML, basophils are difficult be identified their morphology due immaturity or low frequency inhibitors (TKIs) therapy. It important predict responses therapy monitor levels...
To evaluate the genetic polymorphism for DNA microsatellite markers of Egyptian buffalo, 471 unrelated buffalo were genotyped with 11 markers.The data analyzed GenALEx6 software.Nine (82%) polymorphic and two (18%) monomorphic.A total 198 alleles detected, number per marker ranging from 17 (RM28 BM415) to 29 (BMC4203), giving a mean 22±1.302alleles marker.The effective was lower than observed values value 16.502±1.137per most frequent ranged 0.086(BMC4203) 0.127 (BM415).The expected...
Background: The increasing prevalence of drug resistance in cancer therapy underscores the urgent need for novel therapeutic approaches. Dual enzyme inhibitors, targeting critical kinases such as CDK2 and TRKA, represent a promising strategy. goal this investigation was to design, synthesize, evaluate set pyrazolo[1,5-a]pyrimidine derivatives their dual inhibition potential toward TRKA kinases, along with antiproliferative against cell lines. Methods: A (6a–t, 11a–g, 12) synthesized...
(2004). Inhibition and recovery of serum, liver brain acetylcholinesterase activities in rats exposed to new groups O-ethyl phosphoramidates benzo-1,3,2-dioxaphospholenes. Toxicological & Environmental Chemistry: Vol. 86, No. 1, pp. 37-43.
Abstract Background There are several genetic mutations that carry prognostic and predictive values in acute myeloid leukemia (AML). They also implicated disease pathogenesis patient outcome. can be a target of novel therapies for AML. The aim the current study was to investigate value Wilms’ tumor-1 (WT1) genotypes human inhibitory C-type lectin-like (hMICL) receptor expression normal-cytogenetic group patients with Genotyping WT1 done by Rotor Gene real-time polymerase chain reaction (PCR)...
BACKGROUND: Graft versus host disease (GVHD) represents a main cause of post-transplant morbidity and mortality. Ectonucleotidases are one major components purinergic signaling which is the important mediator pathways regulating cellular functions. CD73 most significant member ectonucleotidases. AIM: The aim study was to assess role in development/severity GVHD among patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) SUBJECT AND METHODS: This prospective conducted...
In the sake of enhancing thermal stability α-Tocopheryl acetate (α-TA) and Strawberry Anthocyanins (AN), their encapsulation with starch or β-Cyclodextrin were prepared characterized by UV-Vis IR spectra in addition to analysis.Thermal was investigated comparing thermographs each host guest that complex.Both hosts provided extra both guests where α-TA is stabilized from 230 291 o C complexation 285 β-CD.AN also 40.02 75.57 79.46 β-CD respectively.
Introduction Autologous peripheral blood stem cell transplantation is a 'rescue' of patients' self hematopoietic cells from the myeloablative effects chemotherapy or irradiation. Cryopreservation using 10% dimethyl sulfoxide as cryoprotectant under liquid nitrogen storage conditions (−196°C) for long-term usage well-established procedure, whereas preservation usually performed at 4°C 36-96 h. The aim study was to compare outcome autologous cryopreserved noncryopreserved cells. Patients and...
Abstract: Intestinal obstTUction is an abdominal emergency, and it a common reason for surgical referral. There are many studies that demonstrated the feasibility of laparoscopy in management acute adhesive small bowel obstruction. Although good technique intra-abdominal operative procedures, was contraindicated in intestinal obstTUction. It remains unclear whether patients with obstruction (SBO) might benefit from this or not. 104 were included study divided into two groups, each group...
Background: Spontaneous bacterial peritonitis (SBP) is associated with the highest mortality among end-stage cirrhotic liver disease patients. Neutrophil CD11b expression increases on neutrophil surface within 5 min of exposure to bacteria. Paracentesis remains only accepted method for accurate evaluation patients, many drawbacks; hence, a diagnostic noninvasive marker very high sensitivity and accuracy necessary. Aim study: evaluate as non-invasive biomarker diagnosis SBP, comparing its...