A5012674030- Epigenetics and DNA Methylation
- Ferroptosis and cancer prognosis
- Kruppel-like factors research
- T-cell and Retrovirus Studies
- Cancer Cells and Metastasis
Universidad Autónoma de Madrid
2022-2023
Consejo Superior de Investigaciones Científicas
2023
Hospital Universitario Fundación Jiménez Díaz
2023
Centro de Biología Molecular Severo Ochoa
2022-2023
Summary Despite the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway being frequently altered in T‐ALL/LBL, no specific therapy has been approved for T‐ALL/LBL patients with constitutive signalling by JAK/STAT, so there is an urgent need to identify members that may be potential therapeutic targets. In present study, we searched JAK/STAT potentially modulated through aberrant methylation identified SOCS3 hypermethylation as a recurrent event T‐ALL/LBL....
Abstract In the quest for more effective radiation treatment options that can improve both cell killing and healthy tissue recovery, combined therapies are lately in spotlight. The molecular response to a regime where exposure an initial low dose (priming dose) of ionizing is administered prior subsequent higher (challenging after given latency period have not been thoroughly explored. this study we report on differential either or single challenging mouse vivo human ex thymocytes. A cycle...