Quan Guo

ORCID: 0000-0002-8833-0383
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About
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Research Areas
  • Coronary Interventions and Diagnostics
  • Cardiac Imaging and Diagnostics
  • Cardiac Ischemia and Reperfusion
  • Cardiac Arrest and Resuscitation
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cerebrovascular and Carotid Artery Diseases
  • Pain Management and Treatment
  • Cardiovascular Disease and Adiposity
  • Cardiovascular Issues in Pregnancy
  • Diabetes and associated disorders
  • Lipid metabolism and disorders
  • Acute Myocardial Infarction Research
  • Anesthesia and Pain Management

Zhengzhou University
2022-2025

Zhengzhou Central Hospital
2023-2025

Henan Provincial People's Hospital
2022-2025

First Affiliated Hospital of Xinxiang Medical University
2020

It has been found that individuals with psychiatric illnesses are predisposed to an elevated risk of cardiovascular diseases (CVDs). Mood swing is a clinically relevant characteristic linked disorders. This study examined the possible relationship between genetically predicted mood swings and CVDs risk. In this mediation Mendelian randomization (MR) study, we compiled data from genome-wide association studies examining (n = 451,619) 5 among Europeans, including coronary artery disease (CAD)...

10.1097/md.0000000000042444 article EN cc-by-nc Medicine 2025-05-16

This study aimed to determine the effect of short-term remote ischemic preconditioning (RIPC) on coronary blood flow and microcirculation function using quantitative ratio (QFR) index microcirculatory resistance (IMR). We randomly divided 129 patients undergoing angiography (CAG) into RIPC control groups. Following first CAG, we further unilateral upper limb lower groups for four cycles ischemia/reperfusion circulation; subsequently, performed second CAG. During each contrast-flow QFR...

10.1186/s12872-023-03419-0 article EN cc-by BMC Cardiovascular Disorders 2023-08-17

Background. This study explored the efficacy of “L-sandwich” strategy, which involves implantation stents in main vessel (MV) and shaft side branch (SB) with a drug-coated balloon (DCB) applied to SB ostium, for coronary true bifurcation lesions. Methods Results. Of 99 patients lesions, 38 underwent strategy (group A), 32 two-stent B), 29 single-stent + DCB C). Angiography outcomes (late lumen loss [LLL], minimum diameter [MLD]), clinical (major adverse cardiac events [MACEs]) were analyzed....

10.1155/2023/6889836 article EN cc-by Journal of Interventional Cardiology 2023-03-21

Abstract Background Chronic remote ischemic conditioning (CRIC) has been shown to improve myocardial ischemia in experimental animal studies; however, its effectiveness patients with chronic stable angina (CSA) not investigated. We conducted a proof-of-concept study investigate the efficacy and safety of six-month CRIC treatment CSA. Methods The EARLY-MYO-CSA trial was prospective, randomized, controlled evaluating CSA persistent pectoris despite receiving ≥ 3-month guideline-recommended...

10.1186/s12916-023-03041-z article EN cc-by BMC Medicine 2023-08-25

This study aims to evaluate the long-term outcomes of patients with large coronary arteries (LCA, reference vessel diameter more than 3.0 mm) de novo lesions treated by drug-coated balloon (DCB) versus second-generation drug-eluting stent (sDES) in real-world clinical practice. Between January 2020 and June 2021, 2857 consecutive equal number LCA lesions, including 708 paclitaxel DCB-only (DCB-only cohort) 2149 sDES-only (sDES-only cohort), were enrolled this retrospective study. The primary...

10.1186/s12872-024-04386-w article EN cc-by-nc-nd BMC Cardiovascular Disorders 2024-12-04

ABSTRACT Background After drug-coated balloon (DCB) angioplasty in patients with de novo coronary lesions, dissections can result the continuous presence of thrombi within vessel wall, potentially leading to late luminal loss. Rivaroxaban, a novel oral anticoagulant, may mitigate lumen loss attributable dissection. Objectives This study was conducted evaluate effectiveness and safety low-dose rivaroxaban improving outcomes for following DCB intervention. Methods trial prospective,...

10.1101/2024.01.04.24300877 preprint EN cc-by-nc medRxiv (Cold Spring Harbor Laboratory) 2024-01-07

Even in individuals without diabetes, the incidence of coronary heart disease (CHD) increases with rise fasting plasma glucose (FPG); however, threshold FPG for CHD rural areas China is unclear. We retrospectively examined 2,987 people. Coronary angiography records were used to determine presence as well its severity. Risk factors and relationship between different levels analyzed. After adjusting age, hypertension, dyslipidemia, smoking, drinking, chronic kidney disease, previous ischemic...

10.1155/2020/2348583 article EN cc-by Evidence-based Complementary and Alternative Medicine 2020-01-01

Abstract This study aimed to determine the effect of short-term remote ischemic preconditioning (RIPC) on coronary blood flow and microcirculation function using quantitative ratio (QFR) index microcirculatory resistance (IMR). We randomly divided 129 patients undergoing angiography (CAG) into RIPC control groups. Following first CAG, we further unilateral upper limb lower groups for four cycles ischemia/reperfusion circulation; subsequently, performed second CAG. During each contrast-flow...

10.21203/rs.3.rs-2864055/v1 preprint EN cc-by Research Square (Research Square) 2023-05-03
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