Р. Абдрахманов

ORCID: 0000-0002-8870-8091
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About
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Research Areas
  • BRCA gene mutations in cancer
  • Male Breast Health Studies
  • Multiple and Secondary Primary Cancers
  • Advanced Breast Cancer Therapies
  • Breast Cancer Treatment Studies
  • Advances in Oncology and Radiotherapy
  • Colorectal and Anal Carcinomas
  • Cancer Treatment and Pharmacology
  • Gastric Cancer Management and Outcomes
  • Head and Neck Cancer Studies
  • Radiopharmaceutical Chemistry and Applications
  • Renal cell carcinoma treatment
  • Diversity and Career in Medicine
  • Eicosanoids and Hypertension Pharmacology
  • Esophageal Cancer Research and Treatment
  • Lung Cancer Diagnosis and Treatment
  • Colorectal Cancer Treatments and Studies
  • Cancer-related Molecular Pathways
  • Innovations in Medical Education
  • Metastasis and carcinoma case studies
  • Economic and Financial Impacts of Cancer
  • Electrolyte and hormonal disorders
  • Healthcare professionals’ stress and burnout
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Cancer Immunotherapy and Biomarkers

Kazakh Institute of Oncology and Radiology
2019-2025

Kazakh National Medical University
2022

Chemotherapy Foundation
2022

478 Background: Data on site-specific progression patterns in metastatic renal cell carcinoma (mRCC) treated with immuno-oncology agents are limited. This study aimed to characterize sites of patients receiving nivolumab plus ipilimumab (Nivo-Ipi) or axitinib-based immunotargeted combinations the first-line setting. Methods: A retrospective, observational cohort included clear-cell mRCC who received either Nivo-Ipi (Cohort A) pembrolizumab-axitinib and avelumab-axitinib B) from 2018 2024....

10.1200/jco.2025.43.5_suppl.478 article EN Journal of Clinical Oncology 2025-02-10

Treatment of cancer often requires the use adjuvant chemotherapy (ACT). In real clinical practice, numerous patients suffer from severe toxicity and reduced quality life (QoL). Hence, there is a need to maintain QoL reduce therapy comply with recommended (CT) regimens. The present study focused on effects multi-component nutritional supplement Oncoxin (ONCX) CT-induced in undergoing ACT. A total 133 aged 50-70 years gastric IIB-IIIC or non-small cell lung IIB-IIIA were enrolled study: 84...

10.3892/ol.2019.10868 article EN Oncology Letters 2019-09-13

Relevance: Globocan reported 4,390 new breast cancer cases and 1,654 deaths from in the Republic of Kazakhstan (RK) 2020. Molecular diagnostics includes determination Hormone Receptor (HR), HER2, Ki-67 status to detect patients
 with HR-positive tumors administer effective treatment.
 Methods: This observational study included a retrospective analysis incidence, molecular diagnostics, treatment regimens women confirmed diagnosis aged 18 years old older, registered RK Electronic...

10.52532/2663-4864-2021-4-62-16-23 article EN Oncologia i radiologia Kazakhstana 2021-12-31

The article talks about the Chemotherapy Department of
 Kazakh Research Institute of Oncology and Radiology (KazIOR), which is an important part cancer patients’ treatment
 in Republic Kazakhstan. roll-out clinical chemotherapy as one main treatment methods was
 initiated by Professor S.N. Nugmanov, director KazIOR,
 1963, three years after was established. In
 addition to activities, department staff conducts
 research, participates trials, provides...

10.52532/2521-6414-2020-4-58-107-114 article EN Oncologia i radiologia Kazakhstana 2020-12-31

Results of experimental and clinical studies devoted to urapidil combining central antihypertensive effect with peripheral vasodilatation are discussed. Scope application is described; its good tolerability safety highlighted. Urapidil mode in different situations accompanying by acute increase blood pressure specified.

10.1234/1819-6446-2012-5-703-707 article EN Рациональная фармакотерапия в кардиологии 2012-01-01

Introduction. Treatment of malignant neoplasms often requires adjuvant chemotherapy (ACT). In real-life clinical practice, a high proportion patients develop serious toxicities anticancer therapy. Thus, the need to reduce treatment toxicity while maintaining same dose levels chemotherapeutic agents is pressing challenge in oncology. This article presents results study assessing effects complex nutraceutical Oncoxin on ACT tolerability. Materials and methods. The included 133 aged 50 70 years...

10.18027/2224-5057-2019-9-3-38-47 article EN cc-by Malignant tumours 2019-12-14

of Oncology and Radiology (Ka-zIOR), which is an important part cancer patients' treatment in the Republic Kazakhstan.The roll-out clinical chemotherapy as one main methods was initiated by Professor S.N.Nugmanov, director KazIOR, 1963, three years after Institute established.In addition to activities, department staff conducts research, participates trials, provides consulting methodological assistance consolidating national service, develops guidelines.

10.52532/2663-4864-2020-4-58-107-114 article EN Oncologia i radiologia Kazakhstana 2020-12-31

Relevance: Male breast cancer (BC) is one of the rarest diseases and accounts for 1/100 detected BC cases in both sexes. About 30-70%
 men develop against background gynecomastia, particularly its nodular form. The biology disease differs in
 men, but approaches to diagnostics treatment are usually extrapolated from those used women.
 This study aimed demonstrate results each stage a male patient with treatment.
 Methods: article presents clinical case diagnosed «Cancer...

10.52532/2521-6414-2022-2-64-33-38 article EN Oncologia i radiologia Kazakhstana 2022-06-30

Relevance: Male breast cancer (BC) is one of the rarest diseases and accounts for 1/100 detected BC cases in both sexes. About
 30-70% men develop against background gynecomastia, particularly its nodular form. The biology this
 disease differs men, but approaches to diagnostics treatment are usually extrapolated from those used women.
 This study aimed demonstrate results each stage a male patient with treatment.
 Methods: article presents clinical case diagnosed «Cancer...

10.52532/2663-4864-2022-2-64-33-38 article EN Oncologia i radiologia Kazakhstana 2022-06-30

Relevance: Male breast cancer (BC) has always been behind female BC in detection, treatment, and surveillance. Lower frequency men
 limits the usefulness of screening. However, incidence men is growing.
 This paper demonstrates results surgical treatment typical changes clinical morphological manifestations male breast
 under chemotherapy surgery.
 Methods: The article describes a case patient diagnosed with “Cancer right St III (T4NxM0), edematousinfiltrative form an...

10.52532/2521-6414-2022-4-66-53-58 article EN Oncologia i radiologia Kazakhstana 2022-12-30

Relevance: Male breast cancer (BC) has always been behind female BC in detection, treatment, and surveillance. Lower frequency men
 limits the usefulness of screening. However, incidence men is growing.
 This paper demonstrates results surgical treatment typical changes clinical morphological manifestations male breast
 under chemotherapy surgery.
 Methods: The article describes a case patient diagnosed with “Cancer right St III (T4NxM0), edematousinfiltrative form an...

10.52532/10.52532/2521-6414-2022-4-66-53-58 article EN Oncologia i radiologia Kazakhstana 2022-12-30

Relevance: Male breast cancer (BC) has always been behind female BC in detection, treatment, and surveillance. Lower frequency men limits the usefulness of screening. However, incidence is growing.
 This paper demonstrate results surgical treatment typical changes clinical morphological manifestations male under chemotherapy surgery.
 Methods: The article describes a case patient diagnosed with “Cancer right St III (T4NxM0), edematous-infiltrative form an intraductal component,...

10.52532/2663-4864-2022-4-66-53-58 article EN Oncologia i radiologia Kazakhstana 2022-12-30

Relevance: Globocan reported 4,390 new breast cancer cases and 1,654 deaths from in the Republic of Kazakhstan (RK) in
 2020. Molecular diagnostics includes determination Hormone Receptor (HR), HER2, Ki-67 status to detect patients
 with HR-positive tumors administer effective treatment.
 Methods: This observational study included a retrospective analysis incidence, molecular diagnostics, treatment regimens women confirmed diagnosis aged 18 years old older, registered RK...

10.52532/2521-6414-2021-4-62-16-23 article EN Oncologia i radiologia Kazakhstana 2021-12-31
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