A5075286940- interferon and immune responses
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- RNA and protein synthesis mechanisms
- Peptidase Inhibition and Analysis
- CAR-T cell therapy research
- Cytokine Signaling Pathways and Interactions
- Molecular Biology Techniques and Applications
- Autophagy in Disease and Therapy
- DNA Repair Mechanisms
The University of Texas Health Science Center at San Antonio
2024
Harvard University
2020-2023
Center for Systems Biology
2020
RAD52 functions in homologous recombination (HR): a major pathway for repair of DNA double-strand breaks (DSBs), the most lethal lesion type. HR is also essential faithful segregation chromosomes during gametogenesis. Disfunctions lead to genome instability causing cancer or infertility. Mutations genes BRCA1 and BRCA2 are responsible nearly half all hereditary breast ovarian cancers. While mutations cause no discernible phenotype normal human cells; BRCA1/2-deficient cells, inactivation...