A5054453932- Osteoarthritis Treatment and Mechanisms
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Scoliosis diagnosis and treatment
- Microbial Natural Products and Biosynthesis
- Healthcare Regulation
- Andrographolide Research and Applications
- Tendon Structure and Treatment
- Maternal and Neonatal Healthcare
- Protein Hydrolysis and Bioactive Peptides
- Pharmacological Effects and Assays
- Bone fractures and treatments
- Computational Drug Discovery Methods
- Adipokines, Inflammation, and Metabolic Diseases
- Plant and animal studies
- Protease and Inhibitor Mechanisms
- Knee injuries and reconstruction techniques
- Pain Mechanisms and Treatments
- Rheumatoid Arthritis Research and Therapies
- Bee Products Chemical Analysis
- Insect and Pesticide Research
- Synthesis and biological activity
- Antifungal resistance and susceptibility
- Fungal Biology and Applications
Universidade Federal do Maranhão
2020-2025
Instituto Federal do Maranhão
2024
Hospital Universitário da Universidade Federal do Maranhão
2023
Faculdade Evangélica do Paraná
2016
Bees are of great importance for plant diversity being an important pollinating agents. Stingless bees such as Scaptotrigona affinis postica, is cultivated largely due to the products offered by it. Pollen one these products, which has been highlighted exhibit various therapeutic properties. Considering bioactivity this natural product, study investigated antioxidant, anti-inflammatory, antinociceptive activities, and elucidated chemical composition pollen collected extract postica. Using in...
Objective To demonstrate how a surgical task force can help provide access to procedures for many patients waiting surgery in the Brazilian Unified Health System (Sistema Único de Saúde - SUS, Portuguese) list. Methods This is retrospective cohort study involving 28 on SUS list included pediatric scoliosis force. We analyzed medical records, epidemiological data, and clinical radiographic outcomes. Results The data showed that postoperative outcomes of curve correction complications, such as...
PURPOSE: To evaluate the usefulness of a knee osteoarthritis model through functional, radiological and microscopic changes synovial membrane. METHODS: Forty eight rats were divided randomly into two groups. The first received 0.9% saline in joint corresponded to control group. second was submitted experimental right induced by monosodium iodoacetate All animals subjected comparative tests forced ambulation movements, inability articulate tactile allodynia on day 1 post-experiment (Roto-rod...
Since it acquired pandemic status, SARS-CoV-2 has been causing all kinds of damage over the world. More than 6.3 million people have died, and many cases sequelae are in survivors. Currently, only products available to most world's population fight vaccines, which still need improvement since number new cases, admissions into intensive care units, deaths again reaching worrying rates, makes essential compounds that can be used during infection, reducing impacts disease. Plant metabolites...
Osteoarthritis (OA) is a chronic degenerative disease that has significant global impact. It associated with aging and characterized by widespread joint destruction. Cuminaldehyde biologically active component of essential oils shown promise in the treatment nociceptive inflammatory diseases. This study investigated effects cuminaldehyde on an experimental model osteoarthritis induced rat knees. was found to be as effective indomethacin reducing pain all evaluated tests, including forced...
Osteoarthritis (OA) remains a chronic incurable condition, presenting substantial challenges in treatment. This study explores novel strategy by investigating the concurrent use of cuminaldehyde, natural compound, with indomethacin animal models MIA-induced OA. Our results demonstrate that co-administration cuminaldehyde and does indeed produce superior effect when compared to these compounds individually, significantly enhancing therapeutic outcomes. is evidenced marked reduction...
Background/Objectives: This study evaluates the effect of Mn(II) and Co(II) ions on production anti-Candida metabolites by endophytic fungus Aspergillus sp., isolated from Dizygostemon riparius. The objective was to identify metal-induced secondary with antifungal potential against drug-resistant Candida species. Methods: sp. cultivated in Czapek agar supplemented MnCl₂ (400 µM) or CoCl₂ (200 µM). Metabolite profiles were analyzed using UHPLC-DAD LC-ESI-HRMS, followed structural elucidation...
Resumo Objetivo O objetivo deste estudo é identificar os fatores de risco para o aumento sangramento perioperatório em cirurgias tratamento escoliose. Métodos Estudo coorte prospectivo incluindo 30 pacientes com escoliose idiopática submetidos à instrumentação posterior uso do sistema parafusos pediculares um hospital universitário. Resultados As perdas sanguíneas intraoperatórias totalizaram 798,6 ml ± 340 (24,8% volume sanguíneo). Houve perda maciça sangue 9 pacientes. Em média, a...
Introdução: Com o aumento da incidência de fraturas decorrentes acidentes alto impacto, sistema hastes bloqueadas passou a ser utilizado, tornando-se método escolha nos países onde material está disponível. Objetivo: Comparar internação total, necessidade permanência em unidade terapia intensiva, uso concentrado sangue, tubos drenagem, infecção pós-operatória, reabilitação e qualidade vida pacientes com métodos fixação membros inferiores. Universidade Presidente Dutra. Métodos: Foi realizada...
JustificativaAo observar a lacuna da escassez de trabalhos que abordem diastematomielia tipo 2 e medula ancorada como causadores do quadro escoliose grave descrição técnica cirúrgica adotada para correção, notou-se viabilidade elaborar um trabalho com foco em aspectos corroboram resolução caso. Objetivo(s)Relatar o caso uma congênita secundária 2, bem realizar revisão literatura sobre essas patologias. Método(s)Estudo retrospectivo descritivo base na análise prontuário paciente 17 anos...