A5084642848- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Inflammatory mediators and NSAID effects
- Metastasis and carcinoma case studies
- Viral-associated cancers and disorders
- CNS Lymphoma Diagnosis and Treatment
- Cancer-related gene regulation
- Cancer, Lipids, and Metabolism
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Peroxisome Proliferator-Activated Receptors
- Colorectal and Anal Carcinomas
- Osteoarthritis Treatment and Mechanisms
- Cervical Cancer and HPV Research
- Cytomegalovirus and herpesvirus research
- Radiomics and Machine Learning in Medical Imaging
- Cardiac Arrest and Resuscitation
Stony Brook School
2023
Stony Brook University
2023
Belfast Health and Social Care Trust
2017-2021
Royal Victoria Hospital
2021
University of Ulster
2021
Antrim Area Hospital
2017
University of Pennsylvania
2012
Drexel University
2012
Lymphoepithelioma-like carcinoma (LELC) is an uncommon variant of squamous cell carcinoma, which histologically identical to lymphoepithelial the nasopharynx. LELCs have been reported at a variety sites, including stomach, salivary gland, thymus, cervix, endometrium, breast, skin, bladder, and lung. We report 2 vagina 1 anal canal, first LELC latter site. All 3 neoplasms were diffusely positive with p16 (block-type immunoreactivity) canal lesion contained high-risk human papillomavirus type...
// Stephen McCain 1 , James Trainor 2 Damian T. McManus Úna C. McMenamin McQuaid 3 Victoria Bingham Jacqueline A. Manuel Salto-Tellez Richard Turkington and Helen G. Coleman 1, Cancer Epidemiology Research Group, Centre for Public Health, Queen’s University Belfast, Northern Ireland Department of Pathology, Belfast Health Social Care Trust, Cell Biology, Correspondence to: McCain, email: smccain02@qub.ac.uk Keywords: vitamin D receptor; oesophageal cancer; adenocarcinoma...
// Úna C. McMenamin 1 , James Trainor 2 Helen G. Coleman 5 Damian T. McManus Stephen McQuaid 3 Victoria Bingham Jacqueline Manuel Salto-Tellez Brian Johnston 4 and Richard Turkington Cancer Epidemiology Research Group, Centre for Public Health, Queen's University Belfast, Northern Ireland, UK Department of Pathology, Belfast Health Social Care Trust, Ireland Molecular Pathology Laboratory, Cell Biology, Gastroenterology, Royal Hospital, Correspondence to: McMenamin, email:...
Human herpesvirus-8 (HHV8) is a recognised precursor for number of neoplastic and non-neoplastic processes. Immunosuppressed recipients both solid organ haematopoietic stem cell transplants are at risk life-threatening lytic reactivations HHV8-infected B-lymphocytes, primary infections after receiving grafts from HHV8-seropositive donors more rarely by the direct transplantation malignant Kaposi sarcoma cells seeded within graft tissue. We describe case an HHV8-seronegative patient with...
High prostaglandin endoperoxide synthase-2 (PTGS2) enzyme expression in oesophageal adenocarcinoma has been shown to independently predict poor prognosis; however, the evidence is inconsistent. The aim of this study was investigated association between PTGS2 and prognosis patients with adenocarcinoma.
The left ventricular assist device originated as a means to provide temporary circulatory support for patients suffering from end-stage heart failure. was originally intended serve bridge cardiac transplantation. Increasingly, however, the is being utilized destination therapy those who are not candidates It this utilization that raises additional significant ethical concern related risks and benefits of devices, factors influencing quality life, consequences pertaining end-of-life care.
<h3>Introduction</h3> The most striking epidemiological feature of Oesophageal adenocarcinoma (OAC) is its strong unexplained male predominance, suggesting a protective effect for oestrogens, but few studies have investigated expression sex hormone receptors in OAC. In retrospective cohort OAC patients, we evaluated Oestrogen Receptor (ER) α and β Androgen (AR) tumour associations with recurrence survival. <h3>Methods</h3> We identified 148 patients who underwent neo-adjuvant chemotherapy...
<h3>Background</h3> Vitamin D receptor (VDR) expression has been associated with survival in several cancers. This study aims to evaluate the association between VDR and prognosis oesophageal adenocarcinoma patients. <h3>Methods</h3> The included 130 patients who underwent neo-adjuvant chemotherapy surgery at Northern Ireland Cancer Centre 2004 2012. Formalin fixed paraffin embedded (FFPE) resection specimens matched clinical data were retrieved via Biobank. Tissue microarrays (TMAs) created...